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682 articles
September 202624
Neoplastic mimicry of arterial disease.
Two patients presented with vascular symptoms and were admitted to a vascular surgery unit. Upon further investigation, the underlying cause of their symptoms was determined to be neoplastic rather than vascular in…
Severe, reversible alectinib-induced acute kidney injury requiring dialysis in an elderly patient with metastatic non-small cell lung cancer.
An elderly patient with advanced ALK-rearranged non-small cell lung cancer developed severe acute kidney injury requiring dialysis shortly after starting alectinib.
Germline genomic testing to assess the suitability of stem cell donors in the treatment of haematological malignancy: clinical ethics commentary.
The increasing integration of genomic medicine into routine medical care brings to light issues of complexity and uncertainty in the interpretation of genetic variation.We describe a fictional case study based on our…
Durable remission of sinonasal mucosal melanoma despite early ICI discontinuation and risankizumab treatment for irAEs.
A patient with metastatic sinonasal mucosal melanoma experienced a remarkable and durable response to immune checkpoint inhibitors despite early treatment discontinuation due to severe immune-related adverse events.
Testicular torsion after prior orchiopexy in an older adult: diagnostic pitfalls and the importance of multipoint fixation.
A man in his 60s presented with acute scrotal pain on two occasions, having a history of bilateral orchiopexy due to prior testicular torsion. Despite previous surgeries, recurrent torsion was diagnosed.
An Ovarian Hydatid Cyst in a Woman with Hepatic and Pulmonary Echinococcosis.
A 27-year-old woman presented with nonspecific symptoms leading to the diagnosis of an ovarian hydatid cyst, which is a rare occurrence.
Impulsivity, Compulsivity, Social Inappropriateness, and Other Neuropsychiatric Features in Cerebellar Histiocytosis.
This report describes six patients with multisystem Langerhans cell histiocytosis (LCH) who exhibited neurological and psychiatric disturbances linked to cerebellar lesions.
Splenic variceal haemoperitoneum mimicking splenic trauma managed by transjugular intrahepatic portosystemic shunt.
A man in his 50s presented with abdominal pain and instability after a fall. CT imaging indicated haemoperitoneum and revealed undiagnosed cirrhosis with portal hypertension.
Pneumocystis jirovecii pneumonia in a non-HIV immunocompromised patient presenting with bilateral pneumothoraces.
A non-HIV immunocompromised patient developed Pneumocystis jirovecii pneumonia (PJP) after prolonged corticosteroid therapy, initially presenting with dyspnoea and fever.
Posterior spinal fusion for adolescent idiopathic scoliosis in a Jehovah's Witness.
An adolescent Jehovah's Witness with Lenke type 6C+ adolescent idiopathic scoliosis underwent a 5-6 hour posterior spinal fusion without allogeneic blood transfusion.
Culture-positive left shoulder septic arthritis with suspected contralateral involvement secondary to Staphylococcus aureus bacteraemia.
An elderly diabetic patient presented with bilateral shoulder pain and elevated inflammatory markers, but without fever, erythema, swelling, or warmth, which are typical signs of septic arthritis.
An 18-Year-Old Woman with Abdominal Pain.
An 18-year-old woman presented to the emergency department with acute abdominal pain. Through a systematic approach involving questions, physical examination, and diagnostic testing, the clinical team refined their…
FAN1 mutation and karyomegalic nephropathy in chronic kidney disease.
A middle-aged female with chronic kidney disease presented for renal biopsy, which showed tubular vacuolization, patchy acute injury, and karyomegaly with bizarre nuclei.
Anti-OJ antibody-positive anti-synthetase syndrome associated with hepatocellular carcinoma.
A man in his 70s with hepatocellular carcinoma presented with progressive proximal muscle weakness and dropped head syndrome.
Rare ophthalmic complication of tuberculosis meningitis: tuberculosis orbital apex syndrome.
A woman in her mid-60s presented with orbital apex syndrome, characterized by dysfunction of multiple cranial nerves. Diagnostic challenges arose due to the rarity of tuberculosis-related OAS in non-endemic regions.
Ulcerative Bullosis Diabeticorum in a Man With Chronic, Uncontrolled Diabetes, Uncontrolled Erectile Dysfunction, and Significant Social Barriers to Care.
A 41-year-old man with poorly controlled type 2 diabetes mellitus presented with atypical blisters that progressed to ulcerative bullosis diabeticorum.
Simultaneous Thyroid Eye Disease and IgG4-Related Orbital Disease in a Patient With Diabetes Mellitus: A Case Report.
A 72-year-old man with a history of thyroid eye disease and diabetes presented with progressive proptosis and orbital swelling.
A Novel KCNA1 Variant in a Patient With Tremor and Autism Spectrum Disorder Causes Mixed LOF/GOF Defects of Kv1.1 Channels.
Variants in KCNA1, encoding the Kv1.1 potassium channel, cause neurological disorders including episodic ataxia and developmental and epileptic encephalopathy.
A balloon-like cardiac myxoma mimicking a blood-filled cyst.
A 54-year-old woman presented with exertional dyspnea, chest tightness, and intermittent dizziness. Initial evaluations were unremarkable.
Laparoscopic Management of Isolated Fallopian Tube Torsion in Pregnancy.
A 20-year-old pregnant woman at 28 weeks gestation presented with acute right lower quadrant pain. Diagnostic laparoscopy revealed a necrotic, torsed right fallopian tube alongside a paratubal cyst.
Robotic Splenectomy for Refractory Immune Thrombocytopenic Purpura.
A 40-year-old woman with a 4-year history of immune thrombocytopenic purpura, obesity, and Hashimoto thyroiditis presented with severe thrombocytopenia and abnormal uterine bleeding after failing medical therapy.
Double-switch procedure - Mustard atrial switch, arterial switch and ventricular septal defect closure.
The double-switch operation, which combines atrial and arterial switch procedures, provides the best anatomical repair for congenitally corrected transposition of the great arteries [1].
EVT-Inspired Simplified Negative-Pressure Nasoesophageal Drainage for Cervical Abscess Secondary to Esophageal Perforation.
A 52-year-old man presented with odynophagia and fever after ingesting a fish bone, leading to a diagnosis of cervical esophageal perforation with an associated abscess.
Retinal Features and Preserved Vision in ENPP1 Deficiency: Long-Term Insights from Multimodal Imaging and Electrophysiology.
A male patient with ENPP1 deficiency underwent a comprehensive ophthalmic assessment over ten years. Despite systemic ectopic calcification, his visual acuity showed only slight decline, and multimodal imaging revealed…
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