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782 articles
March 20269
A Rare Case of Slowly Progressive Meningitis Caused by Streptococcus intermedius.
An elderly patient with cancer developed meningitis due to Streptococcus intermedius, with an unusually gradual, subacute-to-chronic course. Blood cultures confirmed S.
Analysis of the efficacy of fosfomycin trometamol in preventing biofilm bacterial infection in double-J stents among diabetic patients and the factors associated with infection.
This prospective randomized controlled trial compared fosfomycin trometamol (FMT) with levofloxacin (LFX) for preventing biofilm-forming bacterial colonization of double-J stents in 100 adults with diabetes.
Post-infectious Basal Ganglia Encephalitis Caused by Mumps: A Case Series.
The report describes five patients with basal ganglia encephalitis associated with mumps infection. They had a recent history of parotitis or febrile illness and serologic evidence of mumps, followed by acute movement…
An 8-month-old infant with hepatic tularemia: a case report.
An 8-month-old infant developed fever up to 40 °C, vomiting, and diarrhea after a nuchal tick bite with local wound infection. Fever persisted despite anti-inflammatory medication and antibiotics.
Harnessing nature: a systematic exploration of in vitro antileishmanial and antihuman African trypanosomal properties in traditional medicinal plants and their active principles.
This PRISMA 2020 systematic review examined in vitro antileishmanial and antitrypanosomal activity reported in studies published from 2003 to 2023.
A first-in-human Phase 1/1b randomized trial evaluating the safety and immunogenicity of a respiratory syncytial virus (RSV) virus-like particle subunit vaccine (IVX-121) in healthy young and older adults.
This randomized Phase 1/1b trial evaluated the safety and immunogenicity of IVX-121, an investigational RSV virus-like particle vaccine, in 90 healthy adults aged 18–45 years and 130 aged 60–75 years.
Severe Transfusion-refractory Cytopenia Mimicking Bone Marrow Failure in a Patient Living with HIV after Antiretroviral Therapy Interruption.
A 43-year-old woman living with HIV presented with life-threatening hematochezia and profound thrombocytopenia after interrupting antiretroviral therapy.
A Transfusion-transmitted Chronic Hepatitis E Virus Infection after Allogeneic Bone Marrow Transplantation with Viral Clearance Following Immunosuppression Tapering.
A 62-year-old woman with myelofibrosis developed liver dysfunction after allogeneic bone marrow transplantation. Testing showed anti-HEV IgA and HEV RNA, and matching viral RNA sequences in the transfusion donor and…
Chlorfenapyr-pyrethroid nets for pyrethroid-resistant malaria vectors: efficacy, resistance risks, and policy implications.
This systematic review assessed the efficacy, resistance risks and policy implications of chlorfenapyr-pyrethroid insecticide-treated nets for pyrethroid-resistant malaria vectors.
February 202615
Vancomycin Effectiveness in Reducing Surgical Site Infection in Posterior Spinal Fusion Surgery: A Retrospective Data Analysis of the STRIVE Trial.
This retrospective analysis of prospectively collected data from the STRIVE trial examined intrawound vancomycin use and outcomes after posterior spinal fusion.
Management of nontuberculous mycobacterial Pulmonary disease refractory to guideline-based therapy: A systematic review.
This systematic review examined management strategies for nontuberculous mycobacterial pulmonary disease (NTM-PD) that does not respond to guideline-based therapy.
Body Composition Changes in Children Living With HIV Initiated on Dolutegravir or Protease Inhibitors in the CHAPAS-4 Trial.
This randomized factorial trial analysis examined body-composition changes over 96 weeks in children with HIV switching to second-line antiretroviral therapy.
Tuberculous Pleurisy Highlighting the Need to Consider Primary Tuberculosis in Interferon-gamma Release Assay-negative Patients.
A 54-year-old man with suspected tuberculous pleurisy initially had a negative interferon-gamma release assay (IGRA) and elevated pleural fluid adenosine deaminase (ADA).
Phlegmonous Gastritis in Chemotherapy-related Neutropenia with Endoscopic Findings that Prompted Early Therapeutic Intervention.
A 56-year-old man with chemotherapy-related neutropenia and immunosuppression presented with shock and epigastric pain. CT showed diffuse gastric wall thickening, while endoscopy demonstrated extensive mucosal injury…
Severe congenital toxoplasmosis with isolated central hypothyroidism: A rare case report.
A preterm newborn at 35 weeks’ gestation had severe congenital toxoplasmosis, confirmed by positive IgM/IgG serology and cerebrospinal fluid PCR.
Safety and immunogenicity of an investigational mRNA-lipid nanoparticle-based monovalent influenza vaccine: Results from a phase 1, randomized, dose-escalation study.
This randomized, controlled, phase 1 dose-escalation study assessed safety and immune responses to a monovalent mRNA-lipid nanoparticle influenza A/H1N1 vaccine in younger adults aged 18–45 years and older adults aged…
Safety and immunogenicity of diphtheria, tetanus and pertussis (acellular, three components) combined vaccine, adsorbed after three-dose priming in 2 months age infants: a randomized, blinded, controlled phase III clinical trial in China.
This randomized, blinded, controlled phase III trial compared a three-component acellular pertussis combination vaccine (DTcP) on two infant schedules with licensed DTaP-IPV-Hib in 1,380 healthy 2-month-old infants in…
Efficacy, immunogenicity, and safety of BCG revaccination against Mycobacterium tuberculosis: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed the efficacy, immunogenicity, and safety of BCG revaccination against tuberculosis. Six randomised controlled trials involving 2400 participants were included.
Comparative evaluation of molecular technologies for the identification of prevalent non-tuberculous mycobacteria in pulmonary infections: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed molecular methods for identifying non-tuberculous mycobacteria (NTM) and detecting antibiotic resistance in human studies published between 2005 and 2024.
Invasive Pneumococcal Disease Presenting with Pyogenic Spondylitis in a Patient on Chronic Hemodialysis Who Previously Received a Pneumococcal Vaccine.
A woman receiving chronic hemodialysis presented with fever during a routine session, without focal signs. Blood cultures grew Streptococcus pneumoniae serotype 38, a non-vaccine serotype, despite prior pneumococcal…
Fatal Fungal Peritonitis Caused by Aspergillus udagawae: An Autopsy Case Report.
A 56-year-old man with chronic progressive pulmonary aspergillosis caused by multidrug-resistant Aspergillus udagawae developed acute abdominal pain.
Levofloxacin-Induced Eosinophilic Pneumonia with Systemic Manifestations: A Case Report and Literature Review.
A 73-year-old man developed diffuse erythema, dyspnea, and renal impairment 22 days after starting levofloxacin. Evaluation showed marked eosinophilia and diffuse ground-glass opacities on chest CT.
Adherence and efficacy of the 0 - 7 - 21-day versus the 0 - 1 - 6-month hepatitis B vaccination schedules among people who use drugs: a two-year randomized controlled trial.
This two-year randomized controlled trial compared hepatitis B vaccination schedules among 1261 HBV-susceptible people who use drugs in detoxification centers and methadone clinics in Xi'an, China.
Prevalence of HIV-associated nephropathy in children: a systematic review with meta-analysis of studies published between 2004 and 2019.
This systematic review and meta-analysis estimated the prevalence of HIV-associated nephropathy among children living with HIV.
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