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1018 articles

May 202624

Case ReportInfectious Diseases

Successful use of outpatient parenteral antimicrobial therapy (OPAT) aztreonam-avibactam in a pediatric case of an infectious pseudoarthrosis caused by NDM-producing Klebsiella pneumoniae and Pseudomonas aeruginosa.

A 9-year-old girl with war-related trauma developed infectious pseudoarthrosis of the distal tibia due to NDM-producing Klebsiella pneumoniae and Pseudomonas aeruginosa.

Int J Infect DisMay 28, 2026Read case
Case ReportOtolaryngology (ENT)

Bioabsorbable Stenting in a Case of Severe Pediatric Posterior Glottic Stenosis.

A 2-year-old girl with transverse myelitis and neuromuscular respiratory failure developed posterior glottic stenosis after multiple intubations.

Ann Otol Rhinol LaryngolMay 28, 2026Read case
Clinical ResearchPediatricsOpen access

Comparison of safety and immunogenicity between high-dose and low-dose quadrivalent influenza vaccines in children aged 6-35 months in China: A randomized, double-blind clinical study.

This randomized, double-blind clinical study evaluated the safety and immunogenicity of high-dose versus low-dose quadrivalent influenza vaccines in 3,000 children aged 6-35 months in China.

Hum Vaccin ImmunotherMay 27, 2026Read summary
Clinical ResearchPediatrics

Sustained and indirect effects of PCV10 reduced-dose schedules on pneumococcal carriage in Viet Nam: a long-term follow-up of a cluster-randomised controlled trial.

This long-term follow-up of a cluster-randomised controlled trial in Nha Trang, Viet Nam, assessed the effects of reduced-dose PCV10 schedules on pneumococcal carriage 5.5 years post-vaccination.

Lancet Infect DisMay 27, 2026Read summary
Clinical ResearchAllergy & Immunology

Exploratory pilot trial of a multicomponent immunonutritional supplement in children with allergic asthma and rhinitis: The INAPRA study.

The INAPRA study was a multicenter, randomized, double-blind, placebo-controlled pilot trial investigating a multicomponent immunonutritional supplement in 40 children aged 5-12 with allergic asthma and rhinitis.

Int ImmunopharmacolMay 27, 2026Read summary
Case ReportInfectious Diseases

Diphtheritic polyneuropathy: Not so uncommon.

This report details four cases of diphtheritic polyneuropathy (DP) identified during a limited outbreak of diphtheria, affecting children who had received their infant vaccinations.

Trop DoctMay 27, 2026Read case
Case ReportPediatrics

Postnatal Care-associated Echovirus 11 Infection in Malaysia: Severe Disease With Variable Outcomes.

Five neonates aged 2–9 days in Kuala Lumpur had laboratory-confirmed echovirus 11 (E11) infection. Four developed multiorgan failure, particularly liver dysfunction, and required intensive care; two died.

Pediatr Infect Dis JMay 27, 2026Read case
Clinical ResearchPediatricsOpen access

Immunogenicity and safety of an investigational quadrivalent measles, mumps, rubella, and varicella vaccine in children aged 4-6 years: A phase II, randomized, multi-country trial.

This phase II, randomized, multi-country trial evaluated the immunogenicity and safety of an investigational quadrivalent measles, mumps, rubella, and varicella vaccine (MMRVNS) in healthy children aged 4-6 years.

Hum Vaccin ImmunotherMay 26, 2026Read summary
Clinical ResearchUrology

Comparative Analysis of Ureteral Reimplantation and Dextranomer/Hyaluronic Acid Injection Between Two Centers With Systematic Review and Meta-Analysis.

This study compared dextranomer/hyaluronic acid (Dx/HA) injection and ureteral reimplantation in children under 18 with recurrent UTIs.

J UrolMay 26, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Utility of a 40-minute LH level after depot leuprolide for diagnosis and treatment monitoring in girls with CPP.

This randomized controlled trial evaluated the utility of luteinizing hormone (LH) levels measured 40 minutes after depot leuprolide acetate (dLA) injection in 132 girls with idiopathic central precocious puberty (CPP).

J Endocrinol InvestMay 26, 2026Read summary
Clinical ResearchPsychiatry

Game-Based Intervention for Bullying: Assessing the Efficacy of the RE Think Therapeutic Game in Primary School Children.

This randomized controlled trial evaluated the RE Think therapeutic game’s impact on emotion regulation and bullying behaviors in 75 primary school children.

J Interpers ViolenceMay 26, 2026Read summary
Clinical ResearchEndocrinology

Effect of Sleep Duration Manipulation on Brain-Derived Neurotrophic Factor in Adolescents at Risk for Type 2 Diabetes: A Randomized Crossover Study.

This randomized crossover study investigated the impact of sleep duration manipulation on serum brain-derived neurotrophic factor (BDNF) levels in adolescents at risk for type 2 diabetes.

J Sleep ResMay 26, 2026Read summary
Clinical ResearchAnesthesiology

Does Use of a Soft Endotracheal Tube Reduce Epistaxis During Pediatric Oral and Maxillofacial Procedures?

This randomized controlled trial evaluated the incidence of epistaxis in 96 pediatric patients undergoing dental procedures with either spiral or RAE nasal endotracheal tubes.

J Oral Maxillofac SurgMay 26, 2026Read summary
Case ReportMedical Genetics

A Case of Multiple Mitochondrial Dysfunctions Syndrome 1 and Review of the Literature.

An infant presented with lactic acidosis, refractory epilepsy with encephalopathy, hyperglycinemia, and severe pulmonary arterial hypertension.

Am J Med Genet AMay 26, 2026Read case
Clinical ResearchPediatricsOpen access

Extended Continuous Positive Airway Pressure in Infants Born Preterm Decreases Intermittent Hypoxemia: A Secondary Analysis of a Randomized Controlled Trial.

This secondary analysis of a randomized controlled trial evaluated the effects of extended continuous positive airway pressure (eCPAP) versus discontinued CPAP (dCPAP) on intermittent hypoxemia (IH) in stable preterm…

J PediatrMay 25, 2026Read summary
Clinical ResearchPediatricsOpen access

Association between packed red blood cell transfusion and clinical deterioration in neonatal necrotizing enterocolitis: a systematic review and meta-analysis.

This systematic review and meta-analysis examined the relationship between packed red blood cell (pRBC) transfusion and clinical deterioration in neonates with necrotizing enterocolitis (NEC).

Ann MedMay 24, 2026Read summary
Case ReportMedical GeneticsOpen access

Dental and Dentofacial Findings in a Child With CHOPS Syndrome Managed Under General Anesthesia.

An 11-year-old male with CHOPS syndrome presented with multiple dental caries. Examination revealed midface hypoplasia, coarse facial features, and intraoral findings including enamel hypoplasia and a high palatal vault.

Int J Paediatr DentMay 24, 2026Read case
Case ReportPediatrics

Multimodal Ultrasound Findings of Pediatric Inflammatory Myofibroblastic Tumor in the Liver: A Case Report.

An 8-year-old girl presented with persistent dizziness, leading to the discovery of a liver lesion. Initial imaging with CT and MRI suggested focal nodular hyperplasia.

J Clin UltrasoundMay 23, 2026Read case
Case ReportPediatrics

Emphysematous pyelonephritis in children: Lessons from a case report and systematic review.

An adolescent girl with Type 1 diabetes presented with class 3A right-sided emphysematous pyelonephritis. She was treated successfully with antibiotics and percutaneous nephrostomy, highlighting the importance of timely…

J Pediatr UrolMay 22, 2026Read case
Clinical ResearchPediatrics

Effect of silver diamine fluoride with or without potassium iodide treatment on retention of composite resin restorations in carious primary molars- a randomized clinical trial.

This randomized clinical trial evaluated the retention of composite resin restorations in carious primary molars among 150 children aged 4-9 years.

J DentMay 22, 2026Read summary
Clinical ResearchPediatrics

Early vs delayed opioid administration for pediatric sickle cell vaso-occlusive crisis: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated early versus delayed opioid administration in pediatric patients with sickle cell vaso-occlusive episodes (VOE).

Am J Emerg MedMay 22, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Complications of calcaneo-stop procedure in pediatric flexible flatfoot: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated complications associated with the calcaneo-stop procedure for treating pediatric flexible flatfoot in patients under 18 years.

J Pediatr Orthop BMay 22, 2026Read summary
Clinical ResearchOphthalmology

Xerophthalmia and ocular manifestations of vitamin A deficiency in children in high-income countries: A systematic review.

Xerophthalmia is a vision-threatening eye condition caused by vitamin A deficiency (VAD). Cases of xerophthalmia in high-income countries (HICs) are vulnerable to misdiagnosis, causing delays in treatment and adverse…

Surv OphthalmolMay 22, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Effectiveness and Safety of Contemporary Drug Regimens for Multidrug- and Extensively Drug-resistant Tuberculosis in Children and Adolescents: A Global Systematic Review and Meta-analysis.

This global systematic review and random-effects meta-analysis assessed treatment outcomes and safety of drug regimens for children and adolescents aged 0–19 years with confirmed or presumed multidrug-resistant…

Pediatr Infect Dis JMay 21, 2026Read summary

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