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1064 articles

June 202624

Clinical ResearchPsychiatry

Breath-hold time and anxiety-related vulnerability: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated maximal voluntary breath-holding time (mvBHT) as a marker of interoceptive tolerance in anxiety disorders, involving 1263 adults.

Biol PsycholJun 9, 2026Read summary
Clinical ResearchPsychiatry

Transportation noise in relation to depression and dementia: A burden of disease study for Europe.

This meta-analysis evaluated the association between transportation noise and the risk of depression and dementia in Europe.

Environ ResJun 9, 2026Read summary
Clinical ResearchMedical Genetics

Effects of Fluoxetine on Cognitive Functioning in Children with Down Syndrome: A Prospective Open-Label Exploratory Study of Safety and Efficacy.

This phase I open-label study evaluated the safety and efficacy of fluoxetine in 14 children with Down syndrome, aged 6-10 years. Over 12 months, fluoxetine was found to be safe, with no serious adverse events reported.

J Child Adolesc PsychopharmacolJun 9, 2026Read summary
Clinical ResearchPsychiatry

Effects of positive psychological interventions on suicide-related outcomes: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effects of positive psychological interventions (PPIs) on suicide-related outcomes across 16 studies.

J Affect DisordJun 8, 2026Read summary
Clinical ResearchPsychiatry

Interactive tele-mental health interventions for maternal depression across perinatal stages: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effectiveness of interactive tele-mental health (TMH) interventions for maternal depression and anxiety across perinatal stages.

J Affect DisordJun 8, 2026Read summary
Clinical ResearchPediatrics

Physical exercise interventions for health outcomes in children and adolescents with attention deficit hyperactivity disorder: An umbrella review with meta-analysis.

This umbrella review and meta-analysis evaluated the impact of physical exercise interventions on health outcomes in children and adolescents with ADHD.

Psychiatry ResJun 8, 2026Read summary
Clinical ResearchPsychiatryOpen access

A pilot randomized clinical trial evaluating the feasibility, acceptability, and preliminary efficacy of a cognitive-behavioral therapy adjunct to support benzodiazepine tapering among primary care patients coprescribed benzodiazepines and opioids.

This pilot randomized clinical trial evaluated the feasibility, acceptability, and preliminary efficacy of cognitive-behavioral therapy (CBT) as an adjunct to benzodiazepine tapering in adults prescribed both…

Psychol Addict BehavJun 8, 2026Read summary
Clinical ResearchGeriatrics

Insomnia and inflammatory exposure impair spatial memory and cognitive mapping in older adults: a randomized controlled trial.

This randomized controlled trial investigated the impact of insomnia and inflammatory exposure on spatial memory and cognitive mapping in 84 older adults aged 60-80.

Brain Behav ImmunJun 8, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Management of gynecomastia in adolescence and adults: the clinical practice guidelines from the Italian Society of Andrology and Sexual Medicine (SIAMS).

The Italian Society of Andrology and Sexual Medicine (SIAMS) developed clinical practice guidelines for managing gynecomastia in adolescents and adults.

J Endocrinol InvestJun 8, 2026Read summary
Clinical ResearchPediatrics

Efficacy of a Brief Video Intervention to Improve Parenting Attitudes, Knowledge, and Use of Time-Out: A Randomized Control Trial.

This randomized controlled trial tested whether a brief educational video could improve caregivers’ knowledge, attitudes, and use of time-out from positive reinforcement (TOPR).

Behav ModifJun 8, 2026Read summary
Clinical ResearchPsychiatryOpen access

Effectiveness of Internet-Delivered Cognitive Behavioural Therapy (ICBT) in Improving Weight-Loss and Psychosocial Well-Being Among Adults With High BMI: A Systematic Review.

This systematic review evaluated the effectiveness of Internet-delivered Cognitive Behavioural Therapy (ICBT) in improving weight loss and psychosocial well-being among adults with a BMI ≥ 25 kg/m².

J Clin NursJun 7, 2026Read summary
Clinical ResearchGeriatrics

Effect of a digital mindfulness intervention for mild-to-moderate late-life depression: A randomized controlled trial.

This randomized controlled trial evaluated the FocusZen Mindfulness Stress Reduction System in 54 older adults with mild-to-moderate late-life depression (LLD).

J Psychiatr ResJun 6, 2026Read summary
Clinical ResearchPsychiatry

Moderate to severe negative symptoms predict low risk of symptoms worsening in schizophrenia patients in CATIE.

This randomized controlled trial analyzed data from 1139 adults with schizophrenia to assess whether baseline negative symptom severity predicts symptom exacerbation risk.

Schizophr ResJun 6, 2026Read summary
Case ReportEndocrinology

Glucose-Dependent Insulinotropic Polypeptide/Glucagon-Like-Peptide-1 Use Following 10-Session Cognitive-Behavioural Therapy for Binge-Eating Disorder: A Single-Case Experimental Design.

A 37-year-old woman with binge-eating disorder and obesity (body mass index 68.9 kg/m²) presented to an outpatient eating-disorder clinic.

Eur Eat Disord RevJun 6, 2026Read case
Clinical ResearchPsychiatry

Changes in anxiety, quality of life, and functioning following psilocybin-assisted therapy in veterans with treatment-resistant depression.

This open-label clinical trial investigated the effects of a single 25-mg dose of psilocybin on anxiety, quality of life, and functioning in veterans with treatment-resistant depression.

J Affect DisordJun 4, 2026Read summary
Clinical ResearchPsychiatry

A qualitative meta-analysis on therapist responsiveness to dissociation: Introducing the dissociation-responsive therapy model.

This qualitative meta-analysis examined how therapists adapt their approaches for clients experiencing dissociation, involving 239 therapists across 16 studies.

Psychotherapy (Chic)Jun 4, 2026Read summary
Clinical ResearchPsychiatryOpen access

Efficacy of pharmacological and microbiota-based therapies in preclinical models of autism spectrum disorder: a systematic review.

This systematic review evaluated the efficacy of pharmacological and microbiota-based therapies in preclinical models of autism spectrum disorder (ASD).

Mol PsychiatryJun 4, 2026Read summary
Clinical ResearchNeurologyOpen access

Low-Frequency STN-DBS for Standing and Gait Initiation in Parkinson's Disease: A Double-Blinded Randomised Cross-Over Feasibility Trial.

This double-blind randomized crossover trial evaluated the effects of low-frequency (60 Hz) STN-DBS on balance in 16 post-operative Parkinson's disease patients.

Neurorehabil Neural RepairJun 4, 2026Read summary
Clinical ResearchNeurology

Aperiodic EEG features of cognition: a systematic review.

This systematic review analyzed 45 studies on aperiodic EEG features and cognition in healthy adults aged 18-65. It found that steeper aperiodic spectra correlated with inhibitory control and conflict resolution, while…

Rev NeurosciJun 4, 2026Read summary
Clinical ResearchPsychiatry

Social deprivation in schizophrenia spectrum disorders: A systematic review.

This systematic review examined the relationship between social deprivation and negative symptoms in schizophrenia spectrum disorders, analyzing 31 studies involving individuals with chronic schizophrenia and…

J Psychiatr ResJun 3, 2026Read summary
Clinical ResearchPsychiatry

The subjective effects of △9-tetrahydrocannabinol: A systematic review and dose-response meta-regression.

This systematic review and meta-analysis examined the subjective effects of Δ9-tetrahydrocannabinol (THC) in 1020 healthy individuals with infrequent cannabis use.

Neurosci Biobehav RevJun 3, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Hormonal contraceptives and women's sleep health: A systematic review.

This systematic review evaluated the impact of hormonal contraceptives on sleep health in women aged 18-50, synthesizing findings from 19 studies.

Sleep Med RevJun 3, 2026Read summary
Clinical ResearchPsychiatry

How machine learning applied on fMRI could improve the prognosis of the post-traumatic stress disorder: A systematic review.

This systematic review examined functional brain differences in individuals with post-traumatic stress disorder (PTSD) compared to healthy controls, utilizing machine learning techniques.

J Affect DisordJun 2, 2026Read summary
Clinical ResearchPsychiatry

Neural correlates of mental illness related stigma: a systematic review of neuroimaging evidence.

This systematic review analyzed six neuroimaging studies involving 251 participants to explore the neural correlates of mental illness stigma.

J Psychiatr ResJun 2, 2026Read summary

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