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353 articles
September 202624
Retinal Features and Preserved Vision in ENPP1 Deficiency: Long-Term Insights from Multimodal Imaging and Electrophysiology.
A male patient with ENPP1 deficiency underwent a comprehensive ophthalmic assessment over ten years. Despite systemic ectopic calcification, his visual acuity showed only slight decline, and multimodal imaging revealed…
Scalp necrosis and visual loss in giant cell arteritis: the importance of recognising atypical cutaneous clues.
A 70-year-old woman presented with left hemifacial pain and bilateral forehead skin plaques, initially diagnosed as shingles.
The effect of 0.1% topical ciclosporin a for 12-weeks on the ocular surface innate and adaptive immune response in dry eye disease: protocol for a randomized controlled clinical trial.
This randomized controlled trial protocol aims to evaluate the effects of 0.1% topical ciclosporin A combined with mineral oil eye drops versus mineral oil eye drops alone on the ocular surface immune response in 60…
Rapid choroidal neovascularization after non-flap internal limiting membrane peeling for macular hole in a patient with AMD: a case report and literature review.
A 70-year-old female with age-related macular degeneration (AMD) underwent uncomplicated macular hole surgery involving non-flap internal limiting membrane (ILM) peeling.
The effect of cycloplegia on corneal power and diameter measured by an auto-kerato-refractometer in presbyopic patients with type 2 diabetes mellitus: a post-hoc analysis of a randomized clinical trial.
This post-hoc analysis of a randomized controlled trial evaluated the impact of cycloplegia on corneal power and diameter in 88 presbyopic patients with type 2 diabetes.
Algorithms for the identification of ophthalmic diseases in medico-administrative databases: A systematic review.
This systematic review evaluated algorithms for identifying key ophthalmic diseases in medico-administrative databases, analyzing 523 algorithms across various studies.
Chronic relapsing inflammatory optic neuropathy misdiagnosed as intermittent angle closure: a diagnostic challenge.
A woman in her 40s experienced recurrent retro-orbital pain and was initially misdiagnosed with migraine and later glaucoma due to suspected intermittent angle closure.
Fine-Tuning, Retrieval-Augmented Generation, and Hybrid Adaptation of Language Models for Clinical Decision-Making in Health Care: Systematic Review.
This systematic review evaluated the effectiveness of fine-tuning, retrieval-augmented generation (RAG), and hybrid adaptation strategies for transformer-based language models in clinical decision-making.
Transient Endothelial Damage Following FS-LASIK Combined With Corneal Cross-Linking Surgery: Case Report.
An 18-year-old male with high myopia underwent FS-LASIK combined with corneal cross-linking. Postoperatively, he exhibited corneal edema and endothelial changes in both eyes by day 3.
Biallelic WDR19 Variants: Systematic Analysis of Genotype-Phenotype Correlations.
Ciliopathies represent a diverse group of inherited disorders resulting from dysfunctional cilia. A rare subset is associated with biallelic variants in WDR19 , with fewer than 100 affected individuals reported…
Preliminary Outcomes of iStent Inject vs Kahook Dual Blade Goniotomy Combined With Phacoemulsification: A Randomized Controlled Trial.
This randomized controlled trial compared the safety and efficacy of phacoemulsification combined with iStent inject (phaco-iStent) versus Kahook Dual Blade goniotomy (phaco-KDB) in 68 eyes with open-angle glaucoma or…
Short-term adjunctive use of a liposomal tear substitute after repeated intravitreal therapy: a randomized pilot study.
This randomized pilot study evaluated the effectiveness of a liposomal tear substitute in reducing dry eye symptoms in patients over 50 undergoing repeated intravitreal therapy.
Biologic Switching Strategies for Anti-Tumor Necrosis Factor Alpha Refractory Noninfectious Uveitis: Systematic Review and Meta-Analysis of Clinical Approach.
This systematic review and meta-analysis assessed biologic switching in patients with noninfectious uveitis refractory to anti-TNFα therapy.
Intravitreal Onchocerca sp. With Concomitant Cerebral MRI Lesion: A Case Report.
A 24-year-old man from Jakarta presented with blurred vision, floaters, ocular discomfort, and headaches, unresponsive to uveitis treatment.
Effect of Bariatric Surgery on Improvement of Retinal Microvasculature in Patients With Obesity: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the impact of bariatric surgery on retinal microvasculature in 283 patients with obesity.
Cryptococcal scleritis mimicking scleromalacia perforans.
An elderly man with diabetes presented with progressive scleral thinning and minimal pain, initially diagnosed as scleromalacia perforans.
Previously unreported pathogenic variant in FOXC1 causing Axenfeld-Rieger syndrome with significant ocular anterior segment dysgenesis.
A patient presented with Axenfeld-Rieger syndrome, exhibiting significant ocular anterior segment dysgenesis. Genetic testing revealed heterozygosity for a previously unreported pathogenic variant in the FOXC1 gene.
Ophthalmic artery occlusion following local hyaluronic acid injection: A case report.
A 46-year-old female experienced sudden vision loss and skin mottling after hyaluronic acid injection into the nasal bridge.
Lipidomic profiles and their relationship to incident diabetic retinopathy in type 2 diabetes: The Fremantle Diabetes Study Phase II.
This exploratory longitudinal study examined whether baseline plasma lipid profiles predicted diabetic retinopathy (DR) in 762 adults with type 2 diabetes.
Clinical Reasoning: A 60-Year-Old Diabetic Woman With Fluctuating Visual Disturbances.
A 60-year-old woman with poorly controlled diabetes presented with fluctuating visual disturbances, including bilateral homonymous visual field defects and positive visual phenomena.
Vogt-Koyanagi-Harada Disease Presenting With Progressive Visual Loss and Multisystem Involvement: A Case Report.
A 55-year-old Indian man presented with a 20-day history of progressive bilateral visual loss, headache, and hearing impairment.
Traumatic canalicular laceration and complex eyelid injury in a newborn delivered by forceps.
A newborn sustained complex upper eyelid lacerations and canalicular injury due to forceps-assisted delivery after obstructed labor.
Effect of a modified soft contact lens combined with a noncontact wide-angle viewing system during vitrectomy.
This randomized controlled trial evaluated the effectiveness of a modified soft contact lens (MSCL) in maintaining visual clarity and protecting the cornea during vitrectomy.
Severe vaso-occlusive lupus retinopathy: Purtscher-like retinopathy: a case report.
A 24-year-old female with systemic lupus erythematosus (SLE) developed blurred vision following COVID-19 infection, later presenting with fever, lymphadenopathy, seizures, and altered consciousness.
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