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1064 articles
October 202624
Amyloid PET Quantitation and Centiloid Thresholds in the Diagnosis of Alzheimer Disease: An Individual Participant Data Meta-Analysis.
This individual participant data meta-analysis examined amyloid PET scans from 49,227 participants across 53 studies to establish Centiloid positivity cutoffs for Alzheimer disease diagnosis.
Leveraging Longitudinal DBS Recordings to Probe Pharmacological Mechanisms: Investigating the Role of Orexin Antagonists on Extended Amygdala Activity.
A patient with severe, treatment-refractory obsessive-compulsive disorder and comorbid insomnia had beta activity recorded longitudinally from the bed nucleus of the stria terminalis (BNST) using implanted deep brain…
Physical activity for psychological and physical well-being in menstruating individuals: an integrative review.
This integrative review synthesised qualitative, quantitative, and mixed-methods research on physical activity and psychological or physical well-being across the menstrual cycle.
Brief social contact videos to promote treatment seeking among young adults with depressive symptoms: Intention change, suicidal ideation, and treatment use in a randomized controlled trial.
This randomized controlled trial tested whether brief social contact videos featuring personal recovery stories increased help-seeking and treatment use among 1,545 young adults aged 18–25 years with depressive…
Cannabis use and subsequent onset of manic symptoms and bipolar disorder: A systematic review and meta-analysis.
This registered systematic review and meta-analysis examined longitudinal observational studies of people without prior bipolar disorder, comparing those exposed and unexposed to cannabis.
Exercise to enhance antipsychotic effectiveness and mitigate metabolic harm: systematic review and meta-analysis.
This systematic review and meta-analysis pooled randomised controlled trials of supervised exercise in adults receiving antipsychotic medication for psychotic disorders.
Maternal circulating cytokine and chemokine levels during pregnancy and risk of autism spectrum disorder in offspring: A systematic review and meta-analysis.
This systematic review and meta-analysis examined whether maternal blood cytokine and chemokine levels during pregnancy were associated with autism in offspring, drawing on seven human observational studies.
Systematic review and meta-analysis: the effectiveness of cognitive behavioral therapy and eye movement desensitization and reprocessing in children and adolescents.
This systematic review and meta-analysis evaluated the effectiveness of cognitive behavioral therapy (CBT) versus eye movement desensitization and reprocessing (EMDR) for treating PTSD in children and adolescents aged…
Efficacy of a Prescription-Based Mobile Digital Therapeutic as an Adjunct to Pharmacotherapy for the Acute Phase of Panic Disorder: Multicenter Randomized Controlled Trial.
This multicenter randomized controlled trial evaluated the efficacy of a prescription-based mobile digital therapeutic (DTx) as an adjunct to pharmacotherapy in 66 patients with acute-phase panic disorder.
Serum ferritin in children with Attention Deficit Hyperactivity Disorder (ADHD): A systematic review and meta-analysis.
This systematic review and meta-analysis examined serum ferritin levels in children with Attention Deficit Hyperactivity Disorder (ADHD) compared to healthy controls.
A Problem-Solving Therapy With Apple Watch Support for College Students With Alcohol Use Disorder Symptoms: Pilot Randomized Controlled Trial.
This pilot randomized controlled trial evaluated the feasibility and preliminary effectiveness of a problem-solving therapy supported by Apple Watch (PST-APPLE) for college students with alcohol use disorder (AUD)…
Effects of Benzodiazepines on Heart Failure Outcomes and Adverse Events: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the impact of benzodiazepines (BZDs) on heart failure (HF) outcomes in high-risk populations.
Drug treatments for fibromyalgia: systematic review and network meta-analysis of randomised trials.
This systematic review and network meta-analysis compared drug treatments for fibromyalgia in adults, including evidence from 151 randomised trials involving 32 592 participants.
Dynamic change patterns in suicidal ideation differ in Brief Cognitive Behavioral Therapy (BCBT) and Present-Centered Therapy (PCT).
This randomized clinical trial examined how five dimensions of suicidal ideation changed during Brief Cognitive Behavioral Therapy (BCBT) versus Present-Centered Therapy (PCT) among high-risk U.S.
Nutraceuticals and phytoceuticals in the treatment of bipolar disorder: A systematic review and network meta-analysis.
This systematic review and network meta-analysis assessed randomized controlled trials of nutraceuticals and phytoceuticals for bipolar disorder. Twenty-eight trials involving 2,222 participants evaluated 22 treatments.
Should I drink water or wine? Impacts of online nutritional counseling on the alcohol consumption of elderly individuals with mild cognitive impairment : Secondary Data Analysis from the RCT "BrainFit-Nutrition".
This secondary data analysis from a randomized controlled trial evaluated the effects of nutritional counseling on alcohol consumption in 189 elderly individuals with mild cognitive impairment (MCI) over 12 months.
Androgen insensitivity syndrome: A case report.
A 29-year-old phenotypic female presented with primary amenorrhea and intermittent abdominal pain. Examination revealed normal breast development, sparse pubic hair, and female external genitalia.
A Randomized Controlled Trial of a Digital Stepped-Care Program to Reduce Anxiety and Depressive Symptoms Among Long-Term Care Workers With Psychological Distress: The REPICAL Study.
The REPICAL study evaluated a digital stepped-care program aimed at reducing anxiety and depressive symptoms among long-term care workers (LTCWs) in Catalonia, Spain.
Attachment styles and problematic involvement in potentially addictive behaviours: A systematic review and meta-analysis.
This systematic review and meta-analysis examined associations between attachment styles and problematic involvement in behaviours described as addictions, using peer-reviewed studies published before July 23rd, 2026.
40 Hz transcutaneous auricular vagus nerve stimulation enhances verbal free recall in healthy adults by modulating frontal theta oscillations.
This randomized, single-blind, sham-controlled, three-arm trial examined whether 20 Hz or 40 Hz transcutaneous auricular vagus nerve stimulation (taVNS) affected verbal free recall and resting-state EEG theta activity…
Irritability in the Mix: An Exploratory Study of the Role of Irritability in Characterising Mood Disorders.
This randomized controlled trial explored the relationship between irritability and mixed states in 82 patients with bipolar disorder over 18 months.
Bipolar Disorder and Perimenopause: An Update.
This systematic review examined the relationship between bipolar disorder (BD) and perimenopause, analyzing 14 studies from various countries.
A 6-Year-Old With Becker Muscular Dystrophy and Catatonia.
A 6-year-old boy presented with acute behavioral changes suggestive of catatonia, including altered speech and awareness. He was found to have previously undiagnosed Becker muscular dystrophy.
Quetiapine modestly improves sleep and breathing but impairs next-day performance in people with obstructive sleep apnea and difficulty maintaining sleep: a randomized controlled trial.
This randomized controlled trial evaluated the effects of 50 mg quetiapine versus placebo in 15 individuals with obstructive sleep apnea (OSA) and difficulty maintaining sleep.
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