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1316 articles
October 202624
Effects of exposure to negative and positive social media content about vaping and nicotine addiction on beliefs and intentions to use e-cigarettes among young adults in the United States: results from a randomized controlled experiment.
This randomized controlled experiment assigned 1,816 young adults in the United States to view real, publicly accessible social media videos presenting nicotine addiction positively, negatively, or in unrelated control…
Effects of transcranial direct current stimulation on nicotine use disorder: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed transcranial direct current stimulation (tDCS) for smoking-related outcomes in people with nicotine use disorder.
Locus coeruleus abnormalities on neuromelanin-sensitive MRI in Parkinson's disease: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed locus coeruleus (LC) integrity on neuromelanin-sensitive MRI in Parkinson’s disease (PD), pooling independent comparisons with healthy controls using random-effects…
Avatar-led digital health intervention for sexual and gender minority young adult smoking cessation: randomized controlled pilot trial.
This randomized controlled pilot trial compared EQQUAL, an Acceptance and Commitment Therapy-based digital smoking cessation program tailored for sexual and gender minority (SGM) young adults, with Smokefree.gov.
Bolus-only versus bolus plus continuous infusion hydromorphone for refractory cancer pain: a prospective, multicenter, randomized noninferiority trial.
This prospective, multicenter, randomized noninferiority trial compared bolus-only patient-controlled intravenous hydromorphone analgesia with bolus plus continuous infusion in patients with refractory cancer pain.
Impact of remote management using patient-reported outcomes on pain and anxiety after breast biopsy: the BIO-PSY randomized controlled trial.
The BIO-PSY French, single-centre, open-label randomised controlled trial assessed whether remote patient-reported outcome (PRO) monitoring with tailored interventions improved pain and anxiety after breast biopsy.
Clinical performance of resin infiltration and different sealant modalities in noncavitated pits and fissures: a split-mouth randomized controlled trial.
This split-mouth randomized controlled trial compared resin infiltration, two sealant approaches, and their combination for noncavitated occlusal lesions in 128 permanent molars from 32 children aged 7–14 years.
Efficacy and Safety of Argatroban as an Adjunct to Antiplatelet Therapy in Ischemic Stroke: An Updated Systematic Review and Meta-analysis.
This systematic review and meta-analysis assessed argatroban added to antiplatelet therapy versus control in acute ischemic stroke.
Novel Imaging Techniques Prior to Surgical Management of Invasive Bladder Cancer: A Systematic Review.
This PRISMA-guided systematic review assessed novel imaging for detecting muscle invasion and nodal disease before surgical management of invasive bladder cancer. It included 33 studies encompassing 4,689 patients.
Maternal and Neonatal Complications in Pregnant Women With Polyendocrine Metabolic Ovarian Syndrome: A Nested Prospective Cohort Study.
This prospective nested cohort study examined associations between polyendocrine metabolic ovarian syndrome (PMOS) and pregnancy outcomes among 3,645 pregnant women with risk factors for hyperglycemia enrolled in an…
Clinical and radiographic success of bioflex versus stainless steel crowns using the hall technique in primary molars: a 12-month randomized controlled trial.
This two-arm randomized controlled trial compared BioFlex crowns (BFCs) with stainless-steel crowns (SSCs), both placed using the Hall Technique, in healthy children aged 4–6 years with carious mandibular second primary…
Crescents in native kidney biopsies from patients with IgA nephropathy and the risk of recurrence after kidney transplantation: a retrospective cohort study, systematic literature review and meta-analysis of observational studies.
This retrospective cohort study, systematic review and meta-analysis examined whether glomerular crescents in native kidney biopsies predict IgA nephropathy (IgAN) recurrence after kidney transplantation.
Early exercise therapy for acute nephrotic syndrome: a randomised clinical trial.
This single-centre randomised controlled trial assessed early exercise therapy in hospitalised adults receiving glucocorticoids for acute nephrotic syndrome.
Firstline treatment with ruxolitinib versus best available therapy in patients with polycythemia vera: results from the randomized RuxoBEAT trial.
The multicenter randomized RuxoBEAT trial compared first-line ruxolitinib (RUX) with best available therapy (BAT) in patients with polycythemia vera.
Randomized controlled trial of a group-based smoking cessation intervention for adults with serious mental illness.
This randomized controlled trial evaluated PARQuit in 99 adults with serious mental illness in the United States. Participants received 12 weeks of cessation counseling and pharmacotherapy and were assigned to…
Patients with MASH experience worse health-related quality of life: a multinational real-world study using LiverMultiScan.
This multinational real-world randomised controlled trial examined health-related quality of life (HRQoL) and liver MRI markers in 802 people with suspected MASLD/MASH across four European countries.
Determining the minimal important difference of EQ-5D-5 L utility values in CIDP patients using data from a large clinical trial.
This analysis of data from the ADHERE randomized controlled trial estimated the minimal important difference (MID) in EQ-5D-5 L utility values for patients with chronic inflammatory demyelinating polyradiculoneuropathy…
Anbalcabtagene autoleucel (PD-1 and TIGIT knockdown CD19 CAR T-cell therapy) for relapsed or refractory LBCL: the CRC01-01 trial.
The multicenter phase 1/2 CRC01-01 trial evaluated anbalcabtagene autoleucel, a CD19 CAR T-cell therapy with PD-1 and TIGIT knockdown, in patients with relapsed or refractory large B-cell lymphoma.
Real-world safety and efficacy of lecanemab in the treatment of Alzheimer's disease: a systematic review and meta-analysis.
This systematic review and meta-analysis pooled real-world studies of lecanemab treatment in people with Alzheimer’s disease, including 37 studies.
From Alert to Action: Electronic Practice Advisory Improves DSMES Referrals Over 18 Months.
This cluster-randomized controlled trial in primary care practices in central North Carolina tested whether an electronic health record best practice advisory (BPA) increased referrals to diabetes self-management…
Effectiveness of cardiac resynchronization therapy in cancer therapy-related cardiac dysfunction: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis assessed cardiac resynchronization therapy (CRT) outcomes in patients with cancer therapy-related cardiac dysfunction (CTRCD).
Evaluating a multi-vaccine respiratory immunization strategy involving SARS-CoV-2, pneumococcal, and influenza vaccines in adults: A randomized, open-label, multicenter, controlled, non-inferiority Phase IV trial in China.
This randomized, open-label, multicenter Phase IV trial in China assessed immunogenicity and safety when adults aged ≥18 years received an inactivated SARS-CoV-2 vaccine with PPV23 and IIV4, compared with separate…
Semaglutide modulates explore/exploit decision-making in major depressive disorder: A randomized clinical trial.
This secondary analysis of a randomized clinical trial examined whether semaglutide affected explore/exploit decision-making in 72 participants with major depressive disorder (MDD).
Calorie-Restricted DASH, Carbohydrate-Restricted, and Low-Purine Diets for Weight Loss and Urate Control in Men With Overweight or Obesity and Hyperuricemia: A Randomized Trial.
This 12-week, open-label, active-comparator randomized trial compared calorie-restricted carbohydrate-restricted, DASH, and low-purine balanced diets in 102 men with overweight or obesity and hyperuricemia.
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