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1333 articles
September 202624
Autologous Hematopoietic Transplantation Reduces Brain Inflammatory and Axoglial Damage Biomarkers in Multiple Sclerosis.
This Phase II multicenter clinical trial investigated the effects of autologous hematopoietic stem cell transplantation (AHSCT) on inflammatory and axoglial damage biomarkers in 24 patients with severe multiple…
Pain outcomes and safety in trigeminal neuralgia: a systematic review and meta-analysis comparing percutaneous balloon compression with microvascular decompression.
This systematic review and meta-analysis evaluated the efficacy and safety of percutaneous balloon compression (PBC) versus microvascular decompression (MVD) in treating trigeminal neuralgia (TN) among 1284 patients.
Sacituzumab tirumotecan in previously treated metastatic triple-negative breast cancer: a detailed safety analysis of the randomized OptiTROP-Breast01 study.
This randomized controlled trial analyzed the safety profile of sacituzumab tirumotecan (sac-TMT) in 262 patients with previously treated metastatic triple-negative breast cancer.
Treat-to-target strategies for low-density lipoprotein cholesterol and triglyceride levels for primary and secondary prevention of cardiovascular disease in adults with dyslipidaemia.
This Cochrane systematic review protocol aims to assess the effectiveness of treat-to-target strategies for managing low-density lipoprotein cholesterol and triglyceride levels in adults with dyslipidaemia.
Prevalence and risk factors for road traffic accidents and mortalities in the Amhara region, Ethiopia: a systematic review and meta-analysis.
This systematic review and meta-analysis examined the prevalence and risk factors of road traffic accidents in the Amhara region of Ethiopia, analyzing data from 12 studies involving 5,222 participants.
Responder analysis of adaptive postural balance cardiac rehabilitation exercise in patients with coronary artery disease and type 2 diabetes: secondary analysis of a randomized trial.
This secondary analysis of a randomized trial evaluated the effects of adaptive postural balance cardiac rehabilitation exercise (APBCRE) versus aerobic exercise (AE) in 167 patients with coronary artery disease and…
Nine-year ocular developmental outcomes after ranibizumab or laser treatment for zone II retinopathy of prematurity: follow-up of a randomized trial cohort.
This study followed a randomized trial cohort to assess 9-year ocular developmental outcomes in children treated with intravitreal ranibizumab (IVR) or laser photocoagulation (LP) for zone II retinopathy of prematurity…
Multicentre randomised controlled trial protocol in China comparing postless hip arthroscopy with conventional perineal post-assisted hip arthroscopy to reduce perineal complications in patients undergoing hip arthroscopy for femoroacetabular impingement: the POSTLESS-HIP trial.
The POSTLESS-HIP trial is a multicentre, prospective, parallel-group, randomised controlled trial in China evaluating postless hip arthroscopy versus conventional perineal post-assisted hip arthroscopy in 270 patients…
Effects of natriuresis-guided diuretic therapy in men and women with acute heart failure: insights from PUSH-AHF.
This exploratory sex-specific analysis of the multicentre randomised PUSH-AHF trial examined natriuresis-guided diuretic therapy versus standard care in 310 patients with acute heart failure, 45% of whom were women.
Systemic and intracranial activity of antibody-drug conjugates in patients with non-small cell lung cancer and brain metastases: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed systemic and intracranial responses to antibody-drug conjugates (ADCs) in patients with non-small cell lung cancer and brain metastases.
Shear wave elastography for assessing lower extremity muscle stiffness after anterior cruciate ligament reconstruction: A systematic review.
This systematic review synthesized studies using shear wave elastography (SWE) to assess lower-extremity muscle stiffness after anterior cruciate ligament reconstruction (ACLR), comparing reconstructed limbs with…
Population Pharmacokinetics and Exposure-response Analysis of Durvalumab in Patients with Limited-stage Small-cell Lung Cancer in the Phase 3 ADRIATIC Study.
The ADRIATIC study evaluated the population pharmacokinetics and exposure-response relationships of durvalumab in patients with limited-stage small-cell lung cancer (LS-SCLC).
The effect of acute pain on proprioceptive performance: A systematic review and meta-analysis.
This systematic review and meta-analysis examined whether acute pain is associated with changes in behavioural proprioception measures.
Current Evidence on Periprocedural Flat-Panel CT in Endovascular Stroke Treatment: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined periprocedural flat-panel CT (FPCT) findings and clinical applications in patients undergoing endovascular stroke treatment.
Healthcare spending and factors associated with fall injury in Australia residential aged care: a cohort analysis.
This cohort analysis examined healthcare spending and factors associated with fall injuries in Australian residential aged care, utilizing data from the Opti-Med trial involving 303 participants aged ≥65 years.
Adherence to medical management of kidney stones: A systematic review.
This systematic review evaluated adherence to AUA guidelines for kidney stone management in adults, analyzing 35 studies with 57,970 patients.
Efficacy of a needle-free blood collection device (PIVO Pro) for avoiding contaminated blood culture sets in Australian emergency departments: protocol for an adaptive group sequential randomised controlled trial.
This study protocol outlines a multicentre, adaptive group sequential randomised controlled trial aimed at evaluating the efficacy of the needle-free blood collection device, PIVO Pro, in reducing blood culture…
Evaluation of a Mental Health Care App-Based Fatigue Management Program for Patients With Inflammatory Bowel Disease in Remission: Protocol for a Randomized Controlled Trial.
This randomized controlled trial aims to evaluate a mobile cognitive behavioral intervention for fatigue management in patients with inflammatory bowel disease (IBD) in remission.
Endovascular Treatment for Patients Aged ≥80 Years with Large Ischemic Stroke.
This randomized controlled trial evaluated the effectiveness and safety of endovascular treatment (EVT) in patients aged ≥80 years with large ischemic stroke.
Intravenous thrombolysis use before interhospital transfer for thrombectomy: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the impact of intravenous thrombolysis (IVT) before interhospital transfer for endovascular thrombectomy (EVT) in patients with large-vessel occlusion acute ischemic…
Prevalence of autoimmune comorbidities in aquaporin 4-immunoglobulin G positive neuromyelitis optica spectrum disorder: a systematic review and meta-analysis.
This systematic review and meta-analysis estimated the prevalence of autoimmune comorbidities among people with aquaporin-4-immunoglobulin G-positive neuromyelitis optica spectrum disorder.
A secondary analysis of the SODa-BIC randomized clinical trial using multiple hierarchical composite outcomes.
This post-hoc analysis of the SODa-BIC randomized trial evaluated the effects of sodium bicarbonate on Major Adverse Kidney Events at 30 days in critically ill patients with metabolic acidosis.
REFRACTORY BENIGN ESOPHAGEAL STRICTURES: A SYSTEMATIC REVIEW OF ENDOSCOPIC THERAPY.
This systematic review evaluated endoscopic therapies for refractory benign esophageal strictures (RBES) across 18 studies involving 473 patients.
Prolonged survival after systemic immune reactivation by aglatimagene besadenovec plus valacyclovir in immune checkpoint inhibitor-refractory non-small cell lung cancer.
This phase 2a clinical trial evaluated the combination of aglatimagene besadenovec and valacyclovir in 76 patients with immune checkpoint inhibitor-refractory non-small cell lung cancer.
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