Trending archive
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1845 articles
July 202624
Long-term disease control of GP2-NTRK1 fusion-positive pancreatic adenocarcinoma with liver metastases using sequential tyrosine receptor kinase inhibitors.
A 78-year-old woman was diagnosed with metastatic pancreatic ductal adenocarcinoma involving the liver. Tumour testing identified a GP2-NTRK1 fusion.
Divergent Radiomolecular Phenotype of Spindle Cell Lipoma: Intense 68 Ga-PSMA Uptake in a Lesion With Mild 18 F-FDG Avidity.
A 68-year-old man with gastric cancer underwent 18 F-fluorodeoxyglucose (FDG) PET/CT, which revealed an incidental subcutaneous lesion suspicious for low-grade sarcoma or metastasis.
The population impact of human papillomavirus vaccination on cancer and pre-cancer outcomes: An umbrella review of meta-analyses.
This umbrella review synthesizes data from 34 meta-analyses to evaluate the impact of HPV vaccination on cancer and pre-cancer outcomes.
Adjuvant chemotherapy intensity and prognosis in completely resected high-grade neuroendocrine lung carcinoma: a post hoc analysis of JCOG1205/1206.
This post hoc analysis of the phase III JCOG1205/1206 trial evaluated the impact of adjuvant chemotherapy intensity on prognosis in 217 patients with completely resected high-grade neuroendocrine lung carcinoma.
Decreased TXNRD1 is associated with resistance to tagraxofusp in blastic plasmacytoid dendritic cell neoplasms, as seen in phase II.
This phase II clinical trial investigated the relationship between TXNRD1 levels and response to tagraxofusp in 12 patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN).
Gastric adenocarcinoma in the excluded stomach after Roux-en-Y gastric bypass: a case series, systematic review, and diagnostic algorithm.
Primary remnant gastric cancer after Roux-en-Y gastric bypass presents a diagnostic challenge, and no consensus indications exist to guide the evaluation of the excluded anatomy when malignancy is suspected.
Polatuzumab Vedotin Plus Rituximab, Gemcitabine, and Oxaliplatin in Relapsed or Refractory Diffuse Large B-Cell Lymphoma: Results From the Phase III, Randomized POLARGO Trial.
The phase III, randomized, open-label POLARGO trial compared polatuzumab vedotin plus rituximab, gemcitabine, and oxaliplatin (Pola-R-GemOx) with R-GemOx in patients with relapsed or refractory diffuse large B-cell…
Multicenter Randomized Trial Evaluating the Safety and Effectiveness of the Instylla Hydrogel Embolic System for Vascular Occlusion of Hypervascular Tumors.
This multicenter randomized controlled trial evaluated the safety and effectiveness of the Instylla Embrace Hydrogel Embolic System (HES) in adults with hypervascular tumors.
Association Between Enfortumab Vedotin-Related Adverse Events and Clinical Outcomes in Advanced Urothelial Carcinoma: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the relationship between enfortumab vedotin (EV)-related adverse events and clinical outcomes in advanced urothelial carcinoma.
Phase II Trial of Nivolumab in Advanced Solid Tumors Based on Genomic Profiling: BELIEVE Trial (NCCH1901) Subcohort.
This Phase II trial evaluated the efficacy and safety of nivolumab in patients with advanced solid tumors based on comprehensive genomic profiling (CGP) results.
Myxoid Variant of Primary Cutaneous Anaplastic Large Cell Lymphoma Mimicking Soft Tissue Sarcoma: Diagnostic Pitfalls and Literature Review.
A 40-year-old man presented with a slowly enlarging ulcerated mass on his left thigh, interpreted radiologically as a superficial soft tissue sarcoma.
Biomarker-Guided Adjuvant Therapy in Stage II/III Colon Cancer: A Systematic Review of Current Evidence and Clinical Implications.
This systematic review synthesised evidence on biomarker-guided adjuvant treatment for resectable stage II/III colon cancer, drawing on 52 studies identified from 1,245 records.
Uptake of breast cancer risk-management strategies among unaffected BRCA 1/2 carriers: a systematic review of international evidence.
This systematic review examined the uptake of breast cancer risk management strategies among unaffected BRCA1/2 carriers, analyzing 32 studies published from 2002 to 2025.
Quality-of-Life in CRPC Patients Treated With Enzalutamide Versus Abiraterone: Impact of Standard and Modified Dosing.
This randomized controlled trial compared the quality of life (QoL) in patients with castration-resistant prostate cancer (CRPC) treated with enzalutamide (ENZ) versus abiraterone (ABI).
Robotic Remnant Total Pancreatectomy After Robotic Pancreaticoduodenectomy (with video).
This report details three cases of robotic remnant total pancreatectomy (R-RTP) performed after robotic pancreaticoduodenectomy (R-PD).
Pleural Effusion Cytology of Metastatic Sclerosing Epithelioid Fibrosarcoma.
A patient presented with a pleural effusion that was found to be metastatic sclerosing epithelioid fibrosarcoma (SEF). Cytological analysis revealed characteristic features of SEF, and immunohistochemistry, particularly…
Biologic versus synthetic meshes in irradiated implant-based breast reconstruction: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the outcomes of biologic versus synthetic meshes in irradiated patients undergoing implant-based breast reconstruction (IBBR).
CD7 chimeric antigen receptor T cells in patients with relapsed or refractory CD7-positive acute myeloid leukemia.
This phase I clinical trial evaluated CD7-targeted CAR-T cell therapy in 14 patients with relapsed or refractory CD7-positive acute myeloid leukemia (AML).
Utilization of Cancer Navigators in the Management of Gastric Cancer: A Systematic Review.
This systematic review evaluated the role of cancer navigation programs in managing gastric cancer, analyzing seven studies with 3465 patients.
Anchor-shaped cutaneous flap for volume replacement in oncoplastic breast-conserving surgery for a lower non-ptotic breast.
Three Japanese patients with early breast cancer involving the lower pole of small, non-ptotic breasts underwent an innovative oncoplastic technique using an anchor-shaped cutaneous flap.
Incidental 18 F-PSMA Uptake in a Traumatic Penile Neuroma Detected in a Patient Undergoing PET/CT Imaging for Prostate Cancer.
An 86-year-old man with recurrent prostate cancer underwent an 18 F-PSMA PET/CT scan, revealing an incidental soft tissue nodule in the penile shaft.
Per- and polyfluoroalkyl substances and the risk of thyroid and breast cancer: Evidence from a meta-analysis and computational toxicology.
This meta-analysis evaluated the association between per- and polyfluoroalkyl substances (PFAS) exposure and the risks of thyroid and breast cancer. The analysis included literature from January 2003 to May 2025.
Dose-response relationship between exercise interventions and quality of life in older adults with cancer: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the impact of exercise interventions on quality of life in 2557 older adults with cancer.
The Lowest PSA Level Achieved Before CRPC Predicts Abiraterone Response But Not Enzalutamide Response in Metastatic CRPC.
This multicenter randomized controlled trial investigated the impact of the lowest prostate-specific antigen (PSA) level before castration-resistant prostate cancer (CRPC) on the efficacy of abiraterone (ABI) and…
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