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1333 articles

September 202624

Clinical ResearchUrology

Medical Expulsive Therapy after Extracorporeal Shock Wave Lithotripsy: A Systematic Review and Network Meta-Analysis.

This systematic review and network meta-analysis evaluated the efficacy and safety of pharmacological interventions for medical expulsive therapy (MET) after extracorporeal shock wave lithotripsy (ESWL) in 3262 patients…

Yonsei Med JSep 24, 2026Read summary
Clinical ResearchPsychiatry

Cannabis use is associated with increased risk of violence: A systematic review and meta-analysis.

This systematic review and meta-analysis examined the relationship between cannabis use and violence, analyzing data from 63 studies involving 265,079 participants.

Psychol MedSep 24, 2026Read summary
Clinical ResearchPsychiatry

Lithium and quetiapine augmentation therapy in treatment-resistant depression with atypical features.

This secondary analysis of the randomised LQD trial assessed whether atypical features influenced outcomes with lithium or quetiapine augmentation in treatment-resistant depression.

Psychiatry ResSep 24, 2026Read summary
Clinical ResearchCardiology

Mitochondrial DNA methylation as a bridge: Linking indoor air purification to alleviated cardiovascular impairments in young adults.

This randomized, double-blind crossover trial examined whether mitochondrial DNA (mtDNA) methylation was associated with fine particulate matter (PM2.5) exposure and cardiovascular indicators in 38 healthy young adults.

Environ ResSep 24, 2026Read summary
Clinical ResearchGeriatrics

Bridging the gap in caregiver support: A systematic review of screening practices in primary care.

This systematic review examined the use of caregiver burden screening practices in primary care, focusing on studies from 2013 to 2023.

Nurse PractSep 24, 2026Read summary
Clinical ResearchOncology (Medical)

Structured exercise interventions and survival outcomes in patients with cancer: systematic review and meta-analysis of randomised controlled trials.

This systematic review and meta-analysis evaluated the impact of structured exercise interventions on survival outcomes in cancer patients.

Br J Sports MedSep 24, 2026Read summary
Clinical ResearchHematologyOpen access

Population pharmacokinetic analysis of pirtobrutinib, a non-covalent BTK inhibitor, in patients with hematological malignancies from the Phase 1/2 BRUIN study.

This population pharmacokinetic analysis evaluated pirtobrutinib, a non-covalent BTK inhibitor, in 595 patients with hematological malignancies from the Phase 1/2 BRUIN study.

Cancer Chemother PharmacolSep 24, 2026Read summary
Clinical ResearchUrologyOpen access

Association of androgen deprivation therapy and acute kidney injury in patients with prostate cancer: a systematic review and meta-analysis of 72,980 patients.

This systematic review and meta-analysis evaluated the association between androgen deprivation therapy (ADT) and acute kidney injury (AKI) in 72,980 prostate cancer patients.

Cancer Chemother PharmacolSep 24, 2026Read summary
Clinical ResearchPediatrics

Parental awareness, attitudes and decision-making of off-label use in children: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated parental awareness and attitudes towards off-label medication use in children. In seven studies, the pooled parental awareness rate was found to be 20.2%.

BMJ Paediatr OpenSep 24, 2026Read summary
Clinical ResearchHematology

Red blood cell transfusion to treat or prevent complications in sickle cell disease: an overview of Cochrane reviews.

This systematic review and meta-analysis evaluated the efficacy of red blood cell (RBC) transfusions in treating or preventing complications in sickle cell disease (SCD) across 17 Cochrane reviews.

Cochrane Database Syst RevSep 24, 2026Read summary
Clinical ResearchOrthopedic Surgery

Comparison of Robotic-Assisted Versus Conventional Total Knee Arthroplasty: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the clinical and radiological outcomes of robotic-assisted total knee arthroplasty (RTKA) compared to conventional total knee arthroplasty (CTKA) across 52 studies.

Int J Med RobotSep 24, 2026Read summary
Clinical ResearchPsychiatry

Zuclopenthixol acetate for acute schizophrenia and similar major mental illnesses.

This systematic review and meta-analysis evaluated the effectiveness of zuclopenthixol acetate for managing acute behavioral disturbances in 714 participants with acute schizophrenia and similar major mental illnesses.

Cochrane Database Syst RevSep 24, 2026Read summary
Clinical ResearchCardiology

Effect of Continuous Positive Airway Pressure on Left Atrial Volume Index in Patients With Stroke and Obstructive Sleep Apnea: A Randomized Trial.

This randomized trial evaluated whether continuous positive airway pressure (CPAP) altered left atrial volume index (LAVI) in patients with stroke and obstructive sleep apnea.

J Am Heart AssocSep 24, 2026Read summary
Clinical ResearchCardiology

Clinical Outcomes of Left Atrial Appendage Occlusion During Cardiac Surgery in Patients Without Atrial Fibrillation: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis combined randomized and observational studies comparing surgical left atrial appendage occlusion (LAAO) with no occlusion during cardiac surgery in patients with sinus rhythm and…

J Am Heart AssocSep 24, 2026Read summary
Clinical ResearchInternal Medicine (General)

Clinical Surveillance Technologies in Nonintensive Care Unit Hospital Settings: Systematic Review and Bayesian Network Meta-Analysis of Randomized Trials.

This systematic review and Bayesian network meta-analysis evaluated the clinical effects of rule-based electronic surveillance (RB-ES), predictive model-based electronic surveillance (PM-ES), and continuous physiologic…

J Med Internet ResSep 24, 2026Read summary
Clinical ResearchOncology (Medical)

Evaluating the Impact of CYP1A2 Inhibition on the Pharmacokinetics of Savolitinib: A Phase 1 Open-Label Study.

This Phase 1 open-label study assessed the effects of CYP1A2 inhibition by fluvoxamine on the pharmacokinetics of savolitinib in 16 healthy male volunteers.

Pharmacol Res PerspectSep 24, 2026Read summary
Clinical ResearchCardiology

Opposite seasonal variation in nighttime and morning blood pressure: a longitudinal study of patients with hypertension.

This longitudinal study examined seasonal variations in nighttime and morning blood pressure (BP) among 419 hypertensive patients using home blood pressure monitoring.

Am J HypertensSep 24, 2026Read summary
Clinical ResearchOncology (Medical)

AdvanTIG-105: a phase I/Ib dose-expansion study of ociperlimab plus tislelizumab with or without chemotherapy in metastatic non-small cell lung cancer and extensive-stage small cell lung cancer.

The AdvanTIG-105 study evaluated the combination of ociperlimab and tislelizumab, with or without chemotherapy, in patients with metastatic non-small cell lung cancer (NSCLC) and extensive-stage small cell lung cancer…

J Immunother CancerSep 24, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Surveillance of antibiotic-resistant bacteria integrating whole genome sequencing and epidemiological information - a global, systematic review, 2012-2023.

This systematic review examined global surveillance systems for antibiotic-resistant bacteria (ARB) integrating whole genome sequencing (WGS) and epidemiological data.

Antimicrob Resist Infect ControlSep 24, 2026Read summary
Clinical ResearchGeriatrics

Associations Between Gut Microbiota and Immune Profiles in Community-Dwelling Older Adults and the Regulatory Role of Polygonatum odoratum.

This randomized controlled trial investigated the effects of Polygonatum odoratum on gut microbiota and immune profiles in 140 community-dwelling older adults aged 60 and above over 90 days.

Aging CellSep 24, 2026Read summary
Clinical ResearchNeurologyOpen access

Pharmacological treatment of sleep disorder phenotypes in Parkinson's disease: a systematic review and meta-analysis of randomised controlled trials.

This systematic review and meta-analysis evaluated the efficacy and safety of pharmacological treatments for sleep disorders in Parkinson's disease, analyzing 29 randomized controlled trials with 1913 participants.

J NeurolSep 24, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Prognostic Value of the C-Reactive Protein-Albumin-Lymphocyte Index in Hepatobiliary and Pancreatic Cancers: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the prognostic value of the C-reactive protein-albumin-lymphocyte (CALLY) index in patients with hepatobiliary and pancreatic cancers.

J Gastrointest CancerSep 24, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Dietary fibre blend improves gut health in patients with irritable bowel syndrome following a low FODMAP diet: a randomised, double-blind control trial.

This randomized, double-blind controlled trial investigated the effects of a 3-week ur gut ® supplementation on gut health in 26 adults with irritable bowel syndrome (IBS) following a low FODMAP diet.

Eur J NutrSep 24, 2026Read summary
Clinical ResearchOtolaryngology (ENT)Open access

Utilization of human amniotic membrane (HAM) in tympanoplasty: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the use of human amniotic membrane (HAM) as a graft material in tympanoplasty, analyzing data from eight studies involving 265 tympanoplasties.

Cell Tissue BankSep 24, 2026Read summary

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