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406 articles

September 202624

Clinical ResearchNeurologyOpen access

Pathogenic properties of myasthenia gravis AChR autoantibodies associate with clinical response to efgartigimod.

This randomized controlled trial investigated the effects of efgartigimod on AChR autoantibody profiles in 50 patients with generalized myasthenia gravis.

J Neurol Neurosurg PsychiatrySep 14, 2026Read summary
Clinical ResearchEndocrinology

Effectiveness of Obesity Management Education for Healthcare Professionals: A Rapid Review and Meta-Analysis.

This meta-analysis evaluated the effectiveness of structured obesity management education for healthcare professionals (HCPs).

Clin ObesSep 12, 2026Read summary
Case ReportInternal Medicine (General)Open access

Kikuchi-Fujimoto Disease Associated with Hashimoto's Thyroiditis: A Case Report.

A 37-year-old woman with a history of Hashimoto's thyroiditis presented with rapidly enlarging cervical lymphadenopathy. Laboratory tests indicated mild anemia and elevated ESR, while ultrasound revealed multiple…

Int Med Case Rep JSep 12, 2026Read case
Clinical ResearchInternal Medicine (General)Open access

Safety Profile of the Non-steroidal Anti-inflammatory Drug Celecoxib in the Short-Term Management of Acute Non-cancer Pain: A Systematic Review with Meta-analysis of Randomised Controlled Trials.

This systematic review and meta-analysis evaluated the safety of celecoxib for short-term management of acute non-cancer pain in 10,693 participants across 50 studies.

DrugsSep 12, 2026Read summary
Clinical ResearchInternal Medicine (General)

Low-carbohydrate diet score subtypes and all-cause mortality in general and chronic disease populations: a systematic review and meta-analysis of prospective cohort studies.

This systematic review and meta-analysis examined the relationship between low-carbohydrate diet (LCD) scores and all-cause mortality in general and chronic disease populations.

BMJ OpenSep 11, 2026Read summary
Clinical ResearchCardiologyOpen access

Opportunistic and systematic screening for atrial fibrillation in adults aged ≥ 65 years in primary care: a systematic review of randomized and cluster randomized trials.

This systematic review evaluated the effectiveness of opportunistic versus systematic atrial fibrillation (AF) screening in adults aged ≥ 65 years.

BMC Cardiovasc DisordSep 11, 2026Read summary
Clinical ResearchGastroenterology

Optimization strategies for care‑giving behaviors of family caregivers for patients with enterostomy: An evidence summary.

This systematic review summarizes evidence on optimizing caregiving behaviors for family caregivers of patients with enterostomy.

PLoS OneSep 10, 2026Read summary
Clinical ResearchCardiologyOpen access

Comparative effects of atorvastatin and rosuvastatin on inflammatory biomarkers: a systematic review and meta-analysis of randomized head-to-head trials.

This systematic review and meta-analysis of 35 randomized controlled trials (n=6,148) compared the effects of atorvastatin and rosuvastatin on inflammatory biomarkers.

BMC Cardiovasc DisordSep 10, 2026Read summary
Clinical ResearchCardiology

Measuring and governing potentially low-value invasive coronary angiography in Europe: a systematic review, construct-specific meta-analysis, and policy framework.

This PRISMA 2020 systematic review and construct-specific random-effects meta-analysis examined indicators used to measure potentially low-value invasive coronary angiography in European health systems.

Health PolicySep 10, 2026Read summary
Clinical ResearchCardiology

All-cause mortality and appropriate implantable cardioverter-defibrillator shocks with first-line catheter ablation versus antiarrhythmic drugs in ischemic ventricular tachycardia: A systematic review and Meta-analysis of randomized controlled trials.

This systematic review and meta-analysis of randomized controlled trials compared first-line catheter ablation with antiarrhythmic drug therapy in antiarrhythmic-naïve patients with ischemic cardiomyopathy and…

Int J CardiolSep 10, 2026Read summary
Clinical ResearchPulmonology

Comorbidities in clinical cohorts of patients with idiopathic pulmonary fibrosis: a systematic review and meta-analysis.

This systematic review and meta-analysis examined the prevalence and impact of comorbidities in 606,398 patients with idiopathic pulmonary fibrosis (IPF).

Eur Respir RevSep 9, 2026Read summary
Clinical ResearchEndocrinology

Global prevalence of metabolic syndrome in adults with obstructive sleep apnea: a systematic review and meta-analysis.

This systematic review and meta-analysis examined the global prevalence of metabolic syndrome (MetS) in adults with obstructive sleep apnea (OSA), analyzing data from 102 studies involving 34,013 adults across 28…

SleepSep 9, 2026Read summary
Clinical ResearchNeurology

Plasma Cluster of Differentiation 147 and Cognitive Impairment After Acute Ischemic Stroke.

This multicenter randomized controlled trial investigated the relationship between plasma CD147 levels and poststroke cognitive impairment (PSCI) in 612 patients with acute ischemic stroke.

J Am Heart AssocSep 9, 2026Read summary
Clinical ResearchRheumatology

Global prevalence and associated factors of metabolic syndrome in patients with systemic lupus erythematosus: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed the global prevalence of metabolic syndrome (MetS) in patients with systemic lupus erythematosus (SLE).

LupusSep 9, 2026Read summary
Clinical ResearchCardiology

Mediators of the Effect of an Educational Intervention on Health-Related Quality of Life in Patients With Heart Failure: A Causal Mediation Analysis.

This causal mediation analysis used data from a randomized controlled trial of 122 patients with heart failure to examine how an educational intervention affected health-related quality of life (HRQOL).

J Cardiovasc NursSep 9, 2026Read summary
Clinical ResearchEmergency Medicine

Access Block and Ambulance Ramping: The Canaries of the Healthcare System.

This systematic review examined factors contributing to hospital access block in Queensland, Australia, utilizing a mixed methods approach.

Emerg Med AustralasSep 8, 2026Read summary
Case ReportOphthalmology

Vogt-Koyanagi-Harada Disease Presenting With Progressive Visual Loss and Multisystem Involvement: A Case Report.

A 55-year-old Indian man presented with a 20-day history of progressive bilateral visual loss, headache, and hearing impairment.

Am J Case RepSep 8, 2026Read case
Clinical ResearchInternal Medicine (General)

Are co-occurring behavioural health risk factors related to reach and efficacy of in-person versus computer-generated brief alcohol interventions? Findings from a randomized controlled trial.

This randomized controlled trial examined the impact of co-occurring behavioral health risk factors (HRFs) on the reach and efficacy of brief alcohol interventions among 961 at-risk alcohol users in a hospital setting.

Patient Educ CounsSep 8, 2026Read summary
Clinical ResearchCardiology

Application effects of information-based health management combined with knowledge-attitude-practice health education model in hypertensive patients.

This randomized controlled trial evaluated the effects of information-based health management combined with the knowledge-attitude-practice (KAP) model in 200 hypertensive patients.

Braz J Med Biol ResSep 7, 2026Read summary
Clinical ResearchInfectious Diseases

Bilingual infographics improve clinical communication and health outcomes among Latino persons with HIV: A multi-site mixed methods study with a randomized controlled trial.

This multi-site randomized controlled trial evaluated the use of bilingual infographics to improve clinical communication and health outcomes among Latino persons with HIV (LPWH).

Patient Educ CounsSep 7, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Empirical Meropenem Versus Piperacillin/Tazobactam for Critically Ill Adults With Sepsis: Feasibility of a Randomised Trial.

The EMPRESS trial is an ongoing randomized controlled trial assessing the feasibility of comparing empirical meropenem versus piperacillin/tazobactam in critically ill adults with sepsis.

Acta Anaesthesiol ScandSep 6, 2026Read summary
Clinical ResearchCardiology

Effect of Non-Soy Legumes on Lipid Profile: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

This systematic review and meta-analysis evaluated the impact of non-soy legumes on lipid profiles in randomized controlled trials.

Nutr RevSep 6, 2026Read summary
Clinical ResearchEndocrinology

Sex differences in the risk of metformin-associated gastrointestinal adverse events: A systematic review and meta-analysis.

This systematic review and meta-analysis examined whether sex is associated with metformin-related gastrointestinal adverse events (GIAEs).

Diabetes Res Clin PractSep 6, 2026Read summary
Case ReportInternal Medicine (General)

Loss of blood pressure control after rifampin initiation: a clinically significant antihypertensive drug-drug interaction.

A man in his early 60s with well-controlled hypertension experienced a sudden increase in blood pressure two weeks after starting isoniazid-rifampin therapy for latent tuberculosis.

BMJ Case RepSep 4, 2026Read case

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