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1333 articles
September 202624
Prenatal allostatic load and adverse pregnancy outcomes: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the relationship between prenatal allostatic load (AL) and adverse pregnancy outcomes (APOs) in a population of 8,795 pregnant women.
Primary Orbital Melanoma: A Systematic Review of Clinical Characteristics, Management and Outcomes.
This systematic review evaluated clinical characteristics, management, and outcomes of 112 patients with histopathologically confirmed primary orbital melanoma (POM).
Adulthood interstitial lung disease due to variants in surfactant related genes: A systematic review.
This systematic review examined the clinical features of interstitial lung disease/pulmonary fibrosis (ILD/PF) in adults with surfactant-related gene (SRG) variants.
Acceptability and efficacy of a smartphone intervention informed by interpersonal psychotherapy for perinatal mental health: A randomized controlled trial.
This randomized controlled trial evaluated the acceptability and efficacy of an interpersonal psychotherapy (IPT)-informed smartphone intervention for perinatal mental health among 350 pregnant women.
Palopegteriparatide for adults with chronic hypoparathyroidism: skeletal dynamics through 3 years of the phase 2 PaTH forward trial.
This randomized controlled trial evaluated the effects of palopegteriparatide in adults with chronic hypoparathyroidism over three years.
Incidence of secondary intraocular lens implantation in school-aged children left aphakic to age 4.5 years in the Infant Aphakia Treatment Study.
This randomized clinical trial assessed the incidence of secondary intraocular lens (IOL) implantation in children left aphakic after unilateral congenital cataract surgery.
Effect of Repositioning Frequency on Bilirubin Levels and Comfort in Neonates Receiving Phototherapy: A Randomized Controlled Trial.
This randomized controlled trial assessed the impact of repositioning frequency on bilirubin levels and comfort in neonates undergoing phototherapy.
Caregiver App Use and Child Behavioral Adherence in Relation to Obesity-Related Outcomes in an mHealth App-Assisted Childhood Obesity Intervention: Secondary Analysis of a Cluster Randomized Trial.
This secondary analysis of a cluster randomized trial involving 684 child-caregiver dyads in China examined the impact of caregiver app-use adherence and child behavioral adherence on obesity-related outcomes.
Incidence and context-specific risk patterns of ureteral avulsion and perforation during ureteroscopy: EAU endourology systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the incidence of ureteral perforation and avulsion during ureteroscopy (URS) for ureteral stones, analyzing 15 studies with 20,635 procedures.
Effectiveness, safety and acceptability of continuous or extended-cycle use of combined oral contraceptives (COCs): a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effectiveness, safety, and acceptability of continuous or extended-cycle combined oral contraceptives (COCs) compared to conventional cyclic regimens.
Meta-analysis of NPC2-mediated cholesterol transport in human cancers as a prognostic biomarker with therapeutic implications.
This meta-analysis evaluated the prognostic significance of NPC2 expression in tumor tissues from 2,097 cancer patients. The study found that elevated NPC2 expression was significantly associated with worse overall…
SILICONE OIL MIGRATION DURING INTRAVITREAL ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR INJECTIONS: A Review of Clinical Evidence and Factors Related to Transmission.
This systematic review evaluated the incidence and mechanisms of silicone oil droplet transmission during intravitreal anti-vascular endothelial growth factor injections.
Increasing topical sunscreen use in German outdoor workers: results of a non-randomised controlled intervention study.
This non-randomised controlled intervention study evaluated a workplace strategy to increase sunscreen use among outdoor workers in Germany. The intervention provided easy access to sunscreen and health education.
Effects of transcendental meditation on mental health and work productivity among university staff in Australia: A randomised controlled trial.
This two-arm, open-label randomised controlled trial assessed transcendental meditation (TM) among staff at an Australian university, comparing five-day training plus regular practice with usual wellbeing resources.
Safety and Immunogenicity of a PD-1-Enhanced HIV-1 Therapeutic DNA Vaccine: A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalating Phase I Clinical Trial in People With HIV-1 on Antiretroviral Therapy.
This randomized, double-blind, placebo-controlled phase I trial evaluated the safety and immunogenicity of ICVAX™, a PD-1-enhanced HIV-1 therapeutic DNA vaccine, in 45 adults with HIV-1 on antiretroviral therapy.
Ivonescimab plus chemotherapy as first-line treatment for advanced thymic carcinoma: preliminary results of a phase II trial with biomarker analyses.
This phase II trial evaluated ivonescimab combined with chemotherapy in seven patients with advanced thymic carcinoma. The study found a promising objective response rate (ORR) of 85.7% and a disease control rate (DCR)…
Effectiveness, safety and acceptability of mifepristone compared with other interventions in reproductive-age women using emergency contraception for the prevention of pregnancy: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effectiveness, safety, and acceptability of mifepristone compared to other emergency contraception methods in reproductive-age women.
Concordance between objective and subjective sleep measures of people with bipolar disorder: A systematic review and a meta-analysis.
This systematic review and meta-analysis examined agreement between objective and subjective sleep measures in people with bipolar disorder.
Contraceptive effectiveness and safety of ormeloxifene: a systematic review.
This systematic review evaluated the contraceptive effectiveness and safety of ormeloxifene among reproductive-age women, analyzing 14 studies.
Approved Medications for Substance Use Disorders: An Umbrella Review of Systematic Reviews and Completed Phase 3 Randomized Controlled Trials.
This PROSPERO-registered umbrella review synthesised systematic reviews and completed phase 3 randomised trials of approved and pipeline medications for substance use disorders worldwide.
EFFECTIVENESS AND SAFETY OF BIOSIMILAR ANTIVASCULAR ENDOTHELIAL GROWTH FACTOR FOR RETINAL DISEASES: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the effectiveness and safety of biosimilar antivascular endothelial growth factor (VEGF) compared to reference anti-VEGF injections for retinal diseases.
A phase 2 pharmacokinetic and pharmacodynamic dose-finding study of oral NEPA for chemotherapy-induced nausea and vomiting in pediatric patients with cancer.
This phase 2 randomized controlled trial assessed the pharmacokinetics, pharmacodynamics, efficacy, and safety of oral netupitant combined with oral palonosetron (NEPA) in pediatric patients (< 18 years) undergoing…
The Role of Eccentric Contraction Training in the Postoperative Rehabilitation of Patients With Total Knee Arthroplasty.
This randomized controlled trial investigated the effects of eccentric contraction training on functional recovery in 44 patients post-total knee arthroplasty (TKA).
Low Prevalence of Exploratory Biochemical Patterns Compatible with Osteomalacia in a Large Cohort of Participants with Low Serum 25-Hydroxyvitamin D Levels.
This study investigated the prevalence of biochemical patterns indicative of osteomalacia in a cohort with low serum 25-hydroxyvitamin D levels.
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