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1297 articles
September 202624
Clinical Outcomes of Left Atrial Appendage Occlusion During Cardiac Surgery in Patients Without Atrial Fibrillation: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis combined randomized and observational studies comparing surgical left atrial appendage occlusion (LAAO) with no occlusion during cardiac surgery in patients with sinus rhythm and…
Clinical Surveillance Technologies in Nonintensive Care Unit Hospital Settings: Systematic Review and Bayesian Network Meta-Analysis of Randomized Trials.
This systematic review and Bayesian network meta-analysis evaluated the clinical effects of rule-based electronic surveillance (RB-ES), predictive model-based electronic surveillance (PM-ES), and continuous physiologic…
Evaluating the Impact of CYP1A2 Inhibition on the Pharmacokinetics of Savolitinib: A Phase 1 Open-Label Study.
This Phase 1 open-label study assessed the effects of CYP1A2 inhibition by fluvoxamine on the pharmacokinetics of savolitinib in 16 healthy male volunteers.
Opposite seasonal variation in nighttime and morning blood pressure: a longitudinal study of patients with hypertension.
This longitudinal study examined seasonal variations in nighttime and morning blood pressure (BP) among 419 hypertensive patients using home blood pressure monitoring.
AdvanTIG-105: a phase I/Ib dose-expansion study of ociperlimab plus tislelizumab with or without chemotherapy in metastatic non-small cell lung cancer and extensive-stage small cell lung cancer.
The AdvanTIG-105 study evaluated the combination of ociperlimab and tislelizumab, with or without chemotherapy, in patients with metastatic non-small cell lung cancer (NSCLC) and extensive-stage small cell lung cancer…
Surveillance of antibiotic-resistant bacteria integrating whole genome sequencing and epidemiological information - a global, systematic review, 2012-2023.
This systematic review examined global surveillance systems for antibiotic-resistant bacteria (ARB) integrating whole genome sequencing (WGS) and epidemiological data.
Associations Between Gut Microbiota and Immune Profiles in Community-Dwelling Older Adults and the Regulatory Role of Polygonatum odoratum.
This randomized controlled trial investigated the effects of Polygonatum odoratum on gut microbiota and immune profiles in 140 community-dwelling older adults aged 60 and above over 90 days.
Pharmacological treatment of sleep disorder phenotypes in Parkinson's disease: a systematic review and meta-analysis of randomised controlled trials.
This systematic review and meta-analysis evaluated the efficacy and safety of pharmacological treatments for sleep disorders in Parkinson's disease, analyzing 29 randomized controlled trials with 1913 participants.
Prognostic Value of the C-Reactive Protein-Albumin-Lymphocyte Index in Hepatobiliary and Pancreatic Cancers: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the prognostic value of the C-reactive protein-albumin-lymphocyte (CALLY) index in patients with hepatobiliary and pancreatic cancers.
Dietary fibre blend improves gut health in patients with irritable bowel syndrome following a low FODMAP diet: a randomised, double-blind control trial.
This randomized, double-blind controlled trial investigated the effects of a 3-week ur gut ® supplementation on gut health in 26 adults with irritable bowel syndrome (IBS) following a low FODMAP diet.
Utilization of human amniotic membrane (HAM) in tympanoplasty: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the use of human amniotic membrane (HAM) as a graft material in tympanoplasty, analyzing data from eight studies involving 265 tympanoplasties.
Prenatal allostatic load and adverse pregnancy outcomes: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the relationship between prenatal allostatic load (AL) and adverse pregnancy outcomes (APOs) in a population of 8,795 pregnant women.
Primary Orbital Melanoma: A Systematic Review of Clinical Characteristics, Management and Outcomes.
This systematic review evaluated clinical characteristics, management, and outcomes of 112 patients with histopathologically confirmed primary orbital melanoma (POM).
Adulthood interstitial lung disease due to variants in surfactant related genes: A systematic review.
This systematic review examined the clinical features of interstitial lung disease/pulmonary fibrosis (ILD/PF) in adults with surfactant-related gene (SRG) variants.
Acceptability and efficacy of a smartphone intervention informed by interpersonal psychotherapy for perinatal mental health: A randomized controlled trial.
This randomized controlled trial evaluated the acceptability and efficacy of an interpersonal psychotherapy (IPT)-informed smartphone intervention for perinatal mental health among 350 pregnant women.
Palopegteriparatide for adults with chronic hypoparathyroidism: skeletal dynamics through 3 years of the phase 2 PaTH forward trial.
This randomized controlled trial evaluated the effects of palopegteriparatide in adults with chronic hypoparathyroidism over three years.
Incidence of secondary intraocular lens implantation in school-aged children left aphakic to age 4.5 years in the Infant Aphakia Treatment Study.
This randomized clinical trial assessed the incidence of secondary intraocular lens (IOL) implantation in children left aphakic after unilateral congenital cataract surgery.
Effect of Repositioning Frequency on Bilirubin Levels and Comfort in Neonates Receiving Phototherapy: A Randomized Controlled Trial.
This randomized controlled trial assessed the impact of repositioning frequency on bilirubin levels and comfort in neonates undergoing phototherapy.
Caregiver App Use and Child Behavioral Adherence in Relation to Obesity-Related Outcomes in an mHealth App-Assisted Childhood Obesity Intervention: Secondary Analysis of a Cluster Randomized Trial.
This secondary analysis of a cluster randomized trial involving 684 child-caregiver dyads in China examined the impact of caregiver app-use adherence and child behavioral adherence on obesity-related outcomes.
Incidence and context-specific risk patterns of ureteral avulsion and perforation during ureteroscopy: EAU endourology systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the incidence of ureteral perforation and avulsion during ureteroscopy (URS) for ureteral stones, analyzing 15 studies with 20,635 procedures.
Sleeve Gastrectomy with Roux-en-y Transit Bipartition versus Sleeve Gastrectomy for the Treatment of Obesity and Reflux: A Multicenter Randomized Controlled Trial.
This multicenter, prospective pilot randomized controlled trial compared sleeve gastrectomy with Roux-en-y transit bipartition (SG-TB) against sleeve gastrectomy (SG) in 120 patients with obesity.
Effectiveness, safety and acceptability of continuous or extended-cycle use of combined oral contraceptives (COCs): a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effectiveness, safety, and acceptability of continuous or extended-cycle combined oral contraceptives (COCs) compared to conventional cyclic regimens.
Meta-analysis of NPC2-mediated cholesterol transport in human cancers as a prognostic biomarker with therapeutic implications.
This meta-analysis evaluated the prognostic significance of NPC2 expression in tumor tissues from 2,097 cancer patients. The study found that elevated NPC2 expression was significantly associated with worse overall…
SILICONE OIL MIGRATION DURING INTRAVITREAL ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR INJECTIONS: A Review of Clinical Evidence and Factors Related to Transmission.
This systematic review evaluated the incidence and mechanisms of silicone oil droplet transmission during intravitreal anti-vascular endothelial growth factor injections.
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