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947 articles

September 202624

Case ReportCardiology

Delayed cardiac conduction disease in a young adult following childhood Chagas infection.

A Bolivian man in his 30s presented to the emergency department with non-exertional chest pain and intermittent second-degree atrioventricular block.

Ir Med JSep 28, 2026Read case
Clinical ResearchCardiologyOpen access

Effects of natriuresis-guided diuretic therapy in men and women with acute heart failure: insights from PUSH-AHF.

This exploratory sex-specific analysis of the multicentre randomised PUSH-AHF trial examined natriuresis-guided diuretic therapy versus standard care in 310 patients with acute heart failure, 45% of whom were women.

Clin Res CardiolSep 28, 2026Read summary
Clinical ResearchNeurology

Association between insular involvement and ECG abnormalities in ischemic stroke: a systematic review and meta-analysis.

This systematic review and meta-analysis examined whether insular involvement in ischemic stroke is associated with ECG abnormalities, using cohort and cross-sectional studies comparing patients with and without insular…

J Clin NeurosciSep 28, 2026Read summary
Case ReportCardiology

The "Spiked Helmet Sign" on Electrocardiogram Following Left Ventricular Assist Device Implantation: A Case Report.

A 68-year-old male with end-stage ischemic cardiomyopathy underwent left ventricular assist device (LVAD) implantation. Shortly after the procedure, his ECG displayed the 'Spiked Helmet Sign' alongside QTc prolongation.

Ann Noninvasive ElectrocardiolSep 27, 2026Read case
Case ReportMedical GeneticsOpen access

Phenotypic spectrum of 19p13.3 microdeletion: a fatal infant case with severe cardiomegaly and gastrointestinal manifestations.

An 8-month-old female infant presented with multisystemic complications, including congenital heart defects, limb anomalies, macrocephaly, and recurrent pulmonary infections.

Mol Biol RepSep 27, 2026Read case
Case ReportCardiology

Left Bundle Branch Area Pacing as a Rescue Strategy After Failed Cardiac Resynchronization Therapy in a Patient With Persistent Left Superior Vena Cava, Absent Coronary Sinus Branches, After Bilateral Maze Procedure: A Case Report.

A 78-year-old man with chronic heart failure and a history of complex cardiac procedures presented for cardiac resynchronization therapy (CRT) due to sick sinus syndrome and left bundle branch block.

Am J Case RepSep 26, 2026Read case
Clinical ResearchPulmonology

Early cardiovascular vulnerability after acute exacerbation of COPD: a time-windowed systematic review and evidence map.

This systematic review and evidence map examined cardiovascular events during and after exacerbations of COPD, asthma, or bronchiectasis, with COPD as the primary evidence base.

Respir MedSep 26, 2026Read summary
Clinical ResearchCardiologyOpen access

GLP-1 Receptor Agonists in Heart Failure: A Systematic Review and Meta-analysis with Phenotype-Specific Effects and Dual Analytical Frameworks.

This systematic review and random-effects meta-analysis assessed GLP-1 receptor agonists across heart-failure phenotypes and trial types, including 14 trials and 15,882 patients with heart failure.

DrugsSep 26, 2026Read summary
Clinical ResearchGeriatrics

Study on blueberries, protein and exercise for improving frailty and cardiovascular disease (STRONG): protocol for a parallel-group randomised controlled superiority trial in older Nova Scotians.

The STRONG study is a parallel-group randomized controlled trial aimed at assessing the impact of a year-long intervention involving blueberries, protein, and exercise on frailty and cardiovascular health in 240 older…

BMJ OpenSep 25, 2026Read summary
Clinical ResearchCardiology

Comparison of bivalirudin versus heparin in percutaneous coronary intervention for patients with acute coronary syndrome: A meta-analysis.

This meta-analysis compared bivalirudin and heparin in patients with acute coronary syndrome undergoing percutaneous coronary intervention, including 11 RCTs and 17 cohort studies with 584,249 patients.

Medicine (Baltimore)Sep 25, 2026Read summary
Case ReportInfectious Diseases

Acute oral Chagas disease following armadillo blood ingestion: a case report.

A 70-year-old man from rural Colombia presented with atrial fibrillation, dyspnea, and palpitations. A blood smear identified Trypanosoma cruzi, confirmed by molecular testing, linked to his ingestion of armadillo blood…

Rev Soc Bras Med TropSep 25, 2026Read case
Clinical ResearchEmergency Medicine

Intraosseous versus intravenous access in adult out-of-hospital cardiac arrest: a Bayesian secondary analysis of the PARAMEDIC-3 randomised controlled trial.

This pre-planned Bayesian secondary analysis of the PARAMEDIC-3 randomised controlled trial compared intraosseous-first with intravenous-first vascular access in adults with out-of-hospital cardiac arrest requiring…

ResuscitationSep 25, 2026Read summary
Clinical ResearchCardiology

The reduction in blood pressure required to reduce arterial stiffness components in SPRINT: a randomized controlled trial.

This analysis of the multicentre SPRINT randomised controlled trial examined whether blood pressure changes were associated with changes in arterial stiffness components over 1 year.

Am J Physiol Heart Circ PhysiolSep 25, 2026Read summary
Clinical ResearchCardiology

Opposite seasonal variation in nighttime and morning blood pressure: a longitudinal study of patients with hypertension.

This longitudinal study examined seasonal variations in nighttime and morning blood pressure (BP) among 419 hypertensive patients using home blood pressure monitoring.

Am J HypertensSep 24, 2026Read summary
Clinical ResearchCardiologyOpen access

Antidepressant use and the risk of atrial fibrillation and ventricular arrhythmia: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the relationship between antidepressant use and the risk of atrial fibrillation (AF) and ventricular arrhythmia/sudden cardiac death (VA/SCD) in a population of over…

Eur J Clin PharmacolSep 24, 2026Read summary
Clinical ResearchCardiology

Survival benefit of guideline-directed medical therapy in older patients with heart failure: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the survival benefits of guideline-directed medical therapy (GDMT) in older patients (≥65 years) with heart failure and reduced ejection fraction (HFrEF).

HeartSep 24, 2026Read summary
Case ReportCardiology

Hypertrophic obstructive cardiomyopathy with associated pulmonary arteriopathy: A histopathologic perspective from sudden cardiac death.

A 52-year-old male with no prior medical history was found dead upon arrival at the emergency department. Autopsy revealed significant left ventricular hypertrophy with a thickness of 3 cm and interventricular septum…

J Forensic Leg MedSep 24, 2026Read case
Clinical ResearchCardiology

Clinical Outcomes of Left Atrial Appendage Occlusion During Cardiac Surgery in Patients Without Atrial Fibrillation: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis combined randomized and observational studies comparing surgical left atrial appendage occlusion (LAAO) with no occlusion during cardiac surgery in patients with sinus rhythm and…

J Am Heart AssocSep 24, 2026Read summary
Clinical ResearchCardiology

Effect of Continuous Positive Airway Pressure on Left Atrial Volume Index in Patients With Stroke and Obstructive Sleep Apnea: A Randomized Trial.

This randomized trial evaluated whether continuous positive airway pressure (CPAP) altered left atrial volume index (LAVI) in patients with stroke and obstructive sleep apnea.

J Am Heart AssocSep 24, 2026Read summary
Clinical ResearchCardiology

Mitochondrial DNA methylation as a bridge: Linking indoor air purification to alleviated cardiovascular impairments in young adults.

This randomized, double-blind crossover trial examined whether mitochondrial DNA (mtDNA) methylation was associated with fine particulate matter (PM2.5) exposure and cardiovascular indicators in 38 healthy young adults.

Environ ResSep 24, 2026Read summary
Clinical ResearchPsychiatry

QTc changes and early major adverse cardiovascular events associated with antidepressant treatment for major depressive disorder in adults: individual participant data network meta-regression of double blind randomised trials.

This network meta-analysis evaluated the impact of various antidepressants on QTc interval and early major adverse cardiovascular events (MACE) in adults with major depressive disorder.

BMJSep 23, 2026Read summary
Clinical ResearchNeurologyOpen access

Psychosocial stress and risk of first-ever stroke: a systematic review and meta-analysis.

This systematic review and meta-analysis examined the link between psychosocial stress and the risk of first-ever stroke in a stroke-free population, analyzing 84 studies with over 4 million participants.

BMC NeurolSep 23, 2026Read summary
Case ReportCardiology

Reversing the Reverse: Nitrate-Enhanced Tc-99m MIBI MPS Unmasking Microvascular Dysfunction in Takayasu Arteritis.

Takayasu Arteritis (TA) is a large vessel vasculitis involving the aorta and its major branches, which could be complicated by significant cardiovascular manifestations.

Clin Nucl MedSep 23, 2026Read case
Clinical ResearchCardiology

suPAR Identifies Treatment-Resistant Inflammatory Risk Beyond hs-CRP in Type 2 Diabetes With Coronary Artery Disease: An Ancillary Analysis of BARI 2D.

This randomized controlled trial analyzed the role of soluble urokinase plasminogen activator receptor (suPAR) in patients with type 2 diabetes and coronary artery disease.

Diabetes CareSep 22, 2026Read summary

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