Hypertrophic obstructive cardiomyopathy with associated pulmonary arteriopathy: A histopathologic perspective from sudden cardiac death.
Priyanshi Gangwal, Siva Sai Kumar Pulagura, Vikas Meshram et al.
✦ AI-curated · Sources linked
Case in brief
A 52-year-old male with no prior medical history was found dead upon arrival at the emergency department. Autopsy revealed significant left ventricular hypertrophy with a thickness of 3 cm and interventricular septum thickness of 2.5 cm. Histopathological analysis showed myocardial disarray and hypertrophy, alongside Grade 2 pulmonary arteriopathy characterized by thickened vascular walls in the lungs, linking HOCM with pulmonary vascular changes.
Diagnostic / clinical pearl
Clinicians should consider the potential for pulmonary arteriopathy in patients with hypertrophic obstructive cardiomyopathy, as it may indicate disease progression and contribute to sudden cardiac events.