Trending archive
Every article that has appeared in Trending stays here. Search by title, journal, author or PMID, and narrow by date.
433 articles
September 202624
Adult-Onset Langerhans Cell Histiocytosis With Calvarial and Hypothalamic Involvement: Two Cases.
This report details two cases of adult-onset Langerhans cell histiocytosis (LCH). The first case involved a 36-year-old woman with a solitary osteolytic lesion in the calvarium, treated with surgical resection and…
Concizumab in patients with hemophilia A or B without inhibitors: 56-week cutoff results of the phase 3 explorer8 study.
The phase 3 explorer8 study evaluated concizumab, a nonfactor replacement therapy, in males aged ≥12 years with hemophilia A or B without inhibitors.
CAR T-cell therapy as a definitive consolidation for older adults with B-ALL in first complete remission.
This phase 1 clinical trial evaluated the safety and efficacy of CD19 CAR T-cell therapy as consolidation treatment in older adults (≥55 years) with B-cell acute lymphoblastic leukemia (B-ALL) in first complete…
Safe Accelerated Venetoclax Escalation: a phase 1b study of obinutuzumab plus venetoclax with daily ramp-up in CLL.
This phase 1b clinical trial evaluated the safety and efficacy of an accelerated 5-day inpatient venetoclax ramp-up in 40 patients with chronic lymphocytic leukemia (CLL).
Long-term outcomes of azacitidine, venetoclax, and gilteritinib in newly diagnosed FLT3-mutated AML.
This phase II clinical trial evaluated the long-term outcomes of azacitidine, venetoclax, and gilteritinib in 30 adults with newly diagnosed FLT3-mutated acute myeloid leukemia (AML) unfit for intensive chemotherapy.
Baricitinib for refractory chronic graft-versus-host disease: results of a phase 1/2 study.
This phase 1/2 study evaluated the safety and efficacy of baricitinib, a JAK 1/2 inhibitor, in 24 adults with refractory chronic graft-versus-host disease (cGVHD) after hematopoietic cell transplantation.
Tuberculosis presenting as dual immune dysregulation: Evans syndrome and haemophagocytic lymphohistiocytosis.
A middle-aged man with no prior health issues presented with a month-long history of fever, dry cough, weight loss, and worsening breathlessness.
Acute haemolytic anaemia precipitated by fava bean ingestion in a patient with previously undiagnosed glucose-6-phosphate dehydrogenase deficiency.
A patient with previously undiagnosed glucose-6-phosphate dehydrogenase (G6PD) deficiency developed acute haemolytic anaemia after consuming fava bean snacks.
Neurologic complications of Evans syndrome.
A patient with severe Evans syndrome developed status epilepticus due to intracranial hemorrhage from profound treatment-refractory thrombocytopenia.
Outcomes of patients with myelofibrosis treated with ruxolitinib and anemia-supporting medications.
This post hoc analysis of the phase 3b JUMP trial examined the effects of adding anemia-supporting medications to ruxolitinib in 101 patients with myelofibrosis and anemia.
Multidisciplinary management of Epstein-Barr virus-associated atraumatic splenic rupture incorporating splenic artery embolisation and intraoperative cell salvage.
A young woman with Epstein-Barr virus-induced hepatitis and splenomegaly presented with abdominal pain and jaundice, later collapsing due to a large haemoperitoneum from atraumatic splenic rupture.
Severe aplastic anemia as a rare autoimmune complication of ankylosing spondylitis: A rare case report.
A 42-year-old male with a history of ankylosing spondylitis presented with recurrent mucocutaneous bleeding, severe fatigue, and transfusion dependence.
Acquired hemophilia a caused by complicated urinary tract infection due to flavobacterium odoratum: A case report and literature review.
A male patient developed acquired hemophilia A (AHA) following ureteroscopic lithotripsy, presenting with hematuria, a right medial thigh hematoma, fever, and prolonged activated partial thromboplastin time (APTT).
CytoSorb Application for Successful Control of Life-Threatening Gastrointestinal Bleeding Following Rivaroxaban Administration.
A 68-year-old man with a history of colonic diverticular disease experienced severe lower gastrointestinal bleeding while on rivaroxaban.
BRAF V600E-mutated marginal zone lymphoma may exhibit features that partially overlap with hairy cell leukemia.
This report describes two cases of BRAF-mutated marginal zone lymphoma (MZL), including a nodal MZL (NMZL) with a BRAF V600E mutation that exhibited partial morphologic and immunophenotypic overlap with hairy cell…
Clinical and molecular spectrum of VEXAS with multiple UBA1 variants: case study and literature review.
A patient with VEXAS syndrome presented with neck swelling, headache, elevated inflammatory markers, leukopenia, macrocytic anemia, and thrombocytopenia. Bone marrow analysis showed no dysplasia or increased blasts.
Azacitidine-Venetoclax or Induction Chemotherapy for Acute Myeloid Leukemia.
This phase 2 randomized trial compared azacitidine plus venetoclax to induction chemotherapy in 172 previously untreated adults with acute myeloid leukemia (AML) eligible for induction.
Systematic review of machine learning approaches for predicting sickle cell crisis and mortality risk at the climate-health nexus.
This systematic review analyzed 34 studies on machine learning models predicting sickle cell anemia (SCA) crises and mortality, focusing on climate-related factors.
Phenome- and laboratory-wide meta-analyses of sickle cell trait reveal multi-system disease associations.
This meta-analysis examined the health outcomes associated with sickle cell trait (SCT) in 4,813 individuals of African genetic ancestry.
Life-threatening multisystem sarcoidosis with neurological, renal, ocular and autoimmune haemolytic manifestations treated with intravenous immunoglobulin, plasma exchange, cyclophosphamide and infliximab.
A patient with multisystem sarcoidosis presented with encephalopathy, acute tubulointerstitial nephritis, optic neuritis, and autoimmune hemolytic anemia, resembling a stroke.
Fatal Transfusion-transmitted Severe Dengue in an Immunocompromised Host: Case Report and Systematic Literature Review.
A stem cell transplant recipient developed severe dengue following a blood transfusion during the 2024 dengue epidemic in Brazil.
Pain Management in Erythromelalgia: A Systematic Review and Graded Appraisal Across Etiological Subtypes.
This systematic review evaluated pain management strategies for erythromelalgia across various etiological subtypes, analyzing 25 studies involving 591 individuals.
Comparative Efficacy of BTK Inhibitors in Treatment-Naïve and Relapsed/Refractory Mantle Cell Lymphoma: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the efficacy of Bruton tyrosine kinase inhibitors (BTKis) in treatment-naïve and relapsed/refractory mantle cell lymphoma (MCL).
Paraneoplastic Myopathy as a Possible Initial Presentation of Sporadic Burkitt Lymphoma in an Immunocompetent Adult: A Case Report.
An immunocompetent adult male presented with acute progressive proximal muscle weakness and elevated creatine phosphokinase levels. Extensive evaluations ruled out autoimmune and metabolic causes.
Stay updated for free
Get the 3 most interesting publications in one specialty each week.
Weekly email. Unsubscribe anytime.
Want this personalized?
Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.
- Your specialties
- Your filters and thresholds
- Clinical Research + Case Reports, tuned separately
- Automatic weekly delivery
- Audio and text
Prefer listening? Personalized audio digests are available with Pro.