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497 articles

September 202624

Case ReportHematology

POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder and skin changes) associated with Castleman disease and latent tuberculosis: a diagnostic challenge.

A woman in her 40s presented with progressive multisystem disease, including chronic distal neuropathy, constitutional decline, lymphadenopathy, and serosal effusions.

BMJ Case RepSep 30, 2026Read case
Case ReportHematology

Masked polycythaemia vera presenting with extensive splanchnic venous thrombosis and mesenteric ischaemia.

A woman in her 60s with masked polycythaemia vera (PV) presented with extensive splanchnic venous thrombosis and mesenteric ischaemia after 5 years of management with phlebotomy and aspirin.

BMJ Case RepSep 30, 2026Read case
Case ReportGeneral Surgery

Marjolin's ulcer developing in a post-traumatic scar: management with negative pressure wound therapy and split-thickness skin grafting.

A man in his 60s presented with a large, non-healing ulcer at the site of a traumatic injury and reconstructive surgery from three decades prior.

BMJ Case RepSep 30, 2026Read case
Case ReportOncology (Medical)

Metastatic muscle invasive bladder cancer in pregnancy.

A woman in her 30s presented during the second trimester with hematuria and left flank pain. MRI identified a T3b bladder tumor with suspected peritoneal invasion.

BMJ Case RepSep 30, 2026Read case
Case ReportUrology

Laparoscopic Treatment of Zinner Syndrome: A Case Report.

A 36-year-old man presented with infertility and chronic pelvic pain, diagnosed with Zinner syndrome, which included left renal agenesis, ureteral atresia, and a large seminal vesicle cyst.

Am J Case RepSep 30, 2026Read case
Case ReportPediatricsOpen access

Isolated clival Langerhans cell histiocytosis in a pediatric patient: systematic review and illustrative case report.

A 3.5-year-old boy presented with isolated clival Langerhans cell histiocytosis, confirmed through histopathological and immunohistochemical evaluation.

Childs Nerv SystSep 30, 2026Read case
Case ReportNephrologyOpen access

FAT1-associated membranous nephropathy after hematopoietic stem cell transplantation: a case report and review of the literature.

A 55-year-old man developed nephrotic syndrome 52 months post-allogeneic hematopoietic stem cell transplantation for acute lymphoblastic leukemia.

CEN Case RepSep 30, 2026Read case
Case ReportOtolaryngology (ENT)Open access

Pyogenic Granuloma in the Sinonasal Cavity: A Potential 38-Year Latency Following Foreign Body Entrapment.

A 43-year-old male presented with left-sided nasal obstruction, rhinorrhea, and hyposmia for two months. Endoscopic evaluation and imaging revealed a highly vascular mass on the left middle turbinate.

Int Med Case Rep JSep 30, 2026Read case
Case ReportPediatricsOpen access

Thalamic Tuberculoma Presenting as Isolated Gait Disturbance Without Systemic or Meningeal Symptoms in a 2-Year-Old Child: A Case Report.

A 2-year-old boy presented with isolated gait disturbance and decreased power on the left side, without systemic or meningeal symptoms.

Int Med Case Rep JSep 30, 2026Read case
Clinical ResearchOncology (Medical)

Unveiling the Prognostic Power of Circulating Tumor DNA in Multiple Myeloma: A Systematic Review and Updated Meta-Analysis.

This systematic review and meta-analysis evaluated the prognostic significance of circulating tumor DNA (ctDNA) in 948 patients with multiple myeloma (MM).

Cancer MedSep 29, 2026Read summary
Case ReportInfectious Diseases

Lumbar spinal brucellosis presenting as an atypical epidural abscess.

A man in his 50s presented with low back pain and lower limb radiculopathy. MRI revealed a ventral epidural collection at L4-L5, resembling a sequestered disc fragment, without significant vertebral or disc involvement.

BMJ Case RepSep 29, 2026Read case
Case ReportNeurologyOpen access

Scleromyxedema-Associated Myopathy and Vacuolar Myopathy with Monoclonal Gammopathy and Stiffness (VAMMGAS) as manifestations of Monoclonal Gammopathy of Clinical Significance (MGCS): a disease spectrum between autophagy dysfunction and inflammation.

This report discusses two patients with Scleromyxedema-Associated Myopathy (SAM) and one with Vacuolar Myopathy with Monoclonal Gammopathy and Stiffness (VAMMGAS), both associated with Monoclonal Gammopathy of Clinical…

J NeurolSep 29, 2026Read case
Case ReportOncology (Medical)

Primary adrenal lymphoma presenting as primary adrenal insufficiency.

A man in his late 60s presented with symptoms of adrenal failure, including anaemia and hypercalcaemia. Initial tests indicated adrenal insufficiency, and imaging showed bilateral adrenal enlargement.

BMJ Case RepSep 28, 2026Read case
Case ReportDermatology

Metastatic dedifferentiated malignant melanoma with spindle cell morphology.

A man in his early 60s presented with a slow-growing skin lesion on his back, which had been present for two decades, and a newly noticed right axillary mass.

BMJ Case RepSep 28, 2026Read case
Case ReportGastroenterology

Crohn's disease unmasks pulmonary sarcoidosis on biologic screening: dual granulomatous pathology responsive to infliximab.

A man in his 30s with a history of ileal Crohn's disease was diagnosed with pulmonary sarcoidosis during routine pre-biologic screening, despite being asymptomatic.

BMJ Case RepSep 28, 2026Read case
Case ReportInfectious Diseases

Localised cutaneous leishmaniasis in an immunosuppressed host: the role for adjuvant photodynamic therapy after incomplete amphotericin B response.

An immunocompromised man in his 70s presented with a 15-year verrucous plaque on the right hallux, initially misdiagnosed as squamous cell carcinoma.

BMJ Case RepSep 28, 2026Read case
Case ReportDermatology

Cutaneous T-cell lymphoma emerging during long-term dupilumab therapy in a patient with longstanding atopic diathesis: diagnostic challenges and mechanistic considerations.

A woman in her 40s with a long history of atopic dermatitis developed patch-stage mycosis fungoides after over 5 years of stable dupilumab therapy.

BMJ Case RepSep 28, 2026Read case
Case ReportPathology (Anatomic & Clinical)

Primary renal glomus tumours of uncertain malignant potential: diagnostic challenges and insights from two instances.

Two elderly patients presented with abdominal pain and were found to have large renal masses on imaging. Both underwent nephrectomy, and histopathological analysis revealed glomus tumors with atypical features but not…

BMJ Case RepSep 28, 2026Read case
Clinical ResearchOncology (Medical)Open access

Circulating tumour DNA and its clinical relevance in predicting progression-free survival and overall survival in patients with advanced breast cancer: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the prognostic value of circulating tumour DNA (ctDNA) in predicting progression-free survival (PFS) and overall survival (OS) in patients with advanced breast cancer…

Breast Cancer Res TreatSep 28, 2026Read summary
Case ReportNeurosurgery

Ventral Cervical Spinal Schwannoma Presenting as Progressive Myelopathy.

A male in his 20s presented with a two-year history of progressive paraparesis and urinary incontinence. Neurological examination revealed signs of spasticity and reduced lower-limb power.

Ir Med JSep 28, 2026Read case
Case ReportInfectious Diseases

Pulmonary Actinomycosis Diagnosed via BALF mNGS in a 53-Year-Old Nonsmoking Man With Pneumoconiosis and Penicillin-Induced Thrombocytopenia: A Case Report.

A 53-year-old nonsmoking man with pneumoconiosis presented with a month-long history of cough and hemoptysis. Imaging revealed bilateral upper-lung masses and lymphadenopathy, leading to a right upper lobectomy under…

Am J Case RepSep 27, 2026Read case
Case ReportOncology (Medical)

Mucinous Adenocarcinoma Arising in a Mature Ovarian Teratoma.

A woman in her 30s presented with a 19 cm right ovarian mass. She underwent extensive surgical intervention, including right salpingo-oophorectomy and lymphadenectomy.

R I Med J (2013)Sep 26, 2026Read case
Case ReportGastroenterology

Phlegmonous Gastritis Refractory to Antibiotics with Subsequent Improvement on Empiric Quadruple Therapy.

A 59-year-old woman presented with two days of severe nausea, vomiting, and inability to tolerate oral intake while on chronic proton-pump inhibitor therapy.

R I Med J (2013)Sep 26, 2026Read case
Case ReportPathology (Anatomic & Clinical)

Somatic PIK3CA and PTEN mutations with endothelial PI3K/AKT/mTOR activation in RAS-negative brain arteriovenous malformations.

This report details two autopsy-confirmed brain arteriovenous malformations (bAVMs) with somatic PIK3CA mutations, one of which also had a PTEN alteration.

J Neuropathol Exp NeurolSep 26, 2026Read case

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