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1316 articles

October 202624

Clinical ResearchPhysical Medicine & Rehabilitation

Selective recovery effects of short-term beetroot juice supplementation after exercise-induced muscle damage in trained female volleyball players.

This randomized, double-blind, placebo-controlled crossover trial examined short-term beetroot juice (BRJ) supplementation after exercise-induced muscle damage in trained female university volleyball players.

J Int Soc Sports NutrOct 20, 2026Read summary
Clinical ResearchPediatricsOpen access

Neonatal gastric perforation: a systematic review and meta-analysis of clinical characteristics, risk factors, surgical management and outcomes.

This systematic review and meta-analysis examined clinical features, risk factors, surgical management and outcomes of neonatal gastric perforation using observational studies of neonates aged 28 days or younger.

Pediatr Surg IntOct 20, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Evidence on information, access frictions, and experience in public healthcare use in rural Bangladesh: a cluster-randomized field experiment.

This cluster-randomized field experiment tested whether information, access frictions, or uncertainty about public care helps explain reliance on private and informal providers among rural Bangladeshi households.

Health Policy PlanOct 19, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Comparison of outcomes after direct extracranial-to-intracranial bypass for moyamoya disease and non-moyamoya pathology: A systematic review and meta-analysis.

This systematic review and meta-analysis compared direct extracranial-to-intracranial (EC-IC) bypass outcomes in adults with moyamoya disease or syndrome (MMD) versus non-moyamoya steno-occlusive disease, mainly…

Neurosurg RevOct 19, 2026Read summary
Clinical ResearchPsychiatry

Characterizing Behavioral Engagement in Smartphone Cognitive Behavioral Therapy for Obsessive Compulsive Disorder: Secondary Analysis of a Randomized Controlled Trial.

This exploratory secondary analysis of a 12-week randomized controlled trial examined behavioral engagement with smartphone cognitive behavioral therapy for obsessive compulsive disorder (OCD) in 60 participants.

JMIR Form ResOct 19, 2026Read summary
Clinical ResearchOrthopedic Surgery

Metal Hypersensitivity Reactions Following Spinal Implants: A Systematic Review.

This systematic review examined clinical presentation, diagnostic approaches, and outcomes of metal hypersensitivity after spinal implant surgery in adults.

JBJS RevOct 19, 2026Read summary
Clinical ResearchGastroenterology

Effects of the GnRH agonist leuprorelin on liver volume in premenopausal women with severe polycystic liver disease.

This prospective, open-label randomized trial evaluated leuprorelin in premenopausal women aged 18–45 years with severe polycystic liver disease (PLD).

Hepatol CommunOct 19, 2026Read summary
Clinical ResearchPsychiatry

The effectiveness of meaning-based interventions in reducing suicide-related vulnerability: A systematic review.

This systematic review examined whether meaning-based interventions affect suicide-related outcomes and how their effects may operate.

Palliat Support CareOct 19, 2026Read summary
Clinical ResearchNeurologyOpen access

Efficacy and safety of tolebrutinib in multiple sclerosis: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed tolebrutinib’s efficacy and safety in multiple sclerosis, drawing on four publications covering four randomised controlled trials and one long-term extension study.

Neurol SciOct 19, 2026Read summary
Clinical ResearchPediatricsOpen access

Comparable efficacy of extraoral and intraoral photobiomodulation in preventing oral mucositis during high-dose methotrexate therapy in pediatric oncology: A single-blind randomized controlled trial.

This single-blind randomized controlled trial compared intraoral (IO) with extraoral (EO) photobiomodulation (PBM) to prevent oral mucositis in 155 children and adolescents receiving high-dose methotrexate for leukemia…

Support Care CancerOct 19, 2026Read summary
Clinical ResearchCardiology

Coronary artery disease management in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation: a systematic review and meta-analysis of randomised controlled trials.

This systematic review and meta-analysis of randomised trials compared coronary revascularisation strategies in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI).

EuroInterventionOct 19, 2026Read summary
Clinical ResearchInfectious Diseases

A process evaluation of community-led distribution of HIV self-testing kits in rural communities in Zimbabwe.

This process evaluation examined community-led HIV self-testing (HIVST) distribution in rural Zimbabwe, within the community-led arm of a cluster-randomized trial comparing it with paid, community-based distribution.

Health Policy PlanOct 19, 2026Read summary
Clinical ResearchPediatricsOpen access

Paediatric Helicobacter pylori infection and allergic and inflammatory diseases: a contemporary systematic review with meta-analysis.

This systematic review and meta-analysis assessed recent evidence on Helicobacter pylori infection and allergic or immune-mediated diseases in children.

Eur J PediatrOct 19, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Loop Taping for Heel Fat Pad Syndrome: A Crossover Pilot Randomized Controlled Trial.

This two-period crossover pilot randomized controlled trial assessed loop taping in adults with heel fat pad syndrome, comparing it with control taping in randomized order.

J Foot Ankle ResOct 19, 2026Read summary
Clinical ResearchGeriatricsOpen access

Outdoor cycling competence and balance control in older adults - cross-sectional analysis of the BiPerAge trial.

This exploratory cross-sectional analysis used baseline data from a two-center randomized controlled trial to examine balance and outdoor cycling competence in 116 community-dwelling adults aged ≥ 65 years who made at…

BMC GeriatrOct 19, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Efficacy and safety of ifupinostat in relapsed or refractory diffuse large B-cell lymphoma: a multicenter, single-arm phase 2 study.

This multicenter, single-arm phase 2 study evaluated intravenous ifupinostat monotherapy in patients with relapsed or refractory diffuse large B-cell lymphoma after at least two prior systemic therapy lines.

Signal Transduct Target TherOct 19, 2026Read summary
Clinical ResearchCardiology

Safety and effectiveness of the Vertex Pulmonary Embolectomy System in acute intermediate-risk pulmonary embolism: the SPIRARE II pivotal trial.

SPIRARE II was a prospective, single-arm, multicentre pivotal trial evaluating the Vertex Pulmonary Embolectomy System for aspiration thrombectomy in patients with acute intermediate-risk pulmonary embolism.

EuroInterventionOct 19, 2026Read summary
Clinical ResearchEndocrinology

Whole egg consumption effects on vitamin D and carotenoids bioavailability in pre- and post-menopausal females: a randomized crossover controlled feeding trial.

This randomized crossover controlled-feeding trial examined whether whole eggs eaten with a cooked vegetable meal altered postprandial nutrient absorption in 9 pre-menopausal and 8 post-menopausal females.

Food FunctOct 19, 2026Read summary
Clinical ResearchFamily Medicine

AI-Based Clinical Decision Support Systems in Primary Care: Systematic Review of Clinical Implementation.

This systematic review assessed the effectiveness and safety of AI-based clinical decision support systems (AI-CDSSs) used by health professionals in primary care, compared with usual care or non-AI decision support.

J Med Internet ResOct 19, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Effectiveness of physical, psychological, and alternative interventions for post-COVID-19 condition: a systematic review.

This systematic review of randomized controlled trials assessed supervised, face-to-face non-pharmacological interventions in adults with WHO-defined post-COVID-19 condition.

J Rehabil MedOct 19, 2026Read summary
Clinical ResearchOrthopedic Surgery

Psychological Factors Associated with Function and Health-Related Quality of Life Outcomes following Total Hip or Knee Arthroplasty: An Umbrella Review of Systematic Reviews.

This umbrella review synthesised high-quality evidence from systematic reviews on psychological factors associated with function and health-related quality of life after total hip or knee arthroplasty.

JBJS RevOct 19, 2026Read summary
Clinical ResearchDermatology

Long-term efficacy of lebrikizumab in treating head, neck and face involvement in patients with moderate-to-severe atopic dermatitis.

This post hoc analysis of phase III trials assessed head, neck, and face (HNF) outcomes with lebrikizumab in adolescents and adults with moderate-to-severe atopic dermatitis.

J Dermatolog TreatOct 19, 2026Read summary
Clinical ResearchPsychiatry

Incorporating Data From Text Messages and Email Into Psychotherapy: Randomized Controlled Trial.

This randomized controlled trial examined whether reviewing personalized text-message data before psychotherapy sessions improved outcomes for 101 adults and older adults receiving treatment for primary depression or…

JMIR Ment HealthOct 19, 2026Read summary
Clinical ResearchOphthalmology

Cost-effectiveness of monotherapy and combination therapy for myopia control in Chinese children.

This network meta-analysis and decision-analytic Markov model assessed the cost-effectiveness of 16 myopia-control strategies for Chinese children and adolescents, modelling eight-year-old children over eight years.

J Glob HealthOct 19, 2026Read summary

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