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1999 articles

September 202624

Clinical ResearchGastroenterology

REFRACTORY BENIGN ESOPHAGEAL STRICTURES: A SYSTEMATIC REVIEW OF ENDOSCOPIC THERAPY.

This systematic review evaluated endoscopic therapies for refractory benign esophageal strictures (RBES) across 18 studies involving 473 patients.

Arq GastroenterolSep 28, 2026Read summary
Clinical ResearchOncology (Medical)

Prolonged survival after systemic immune reactivation by aglatimagene besadenovec plus valacyclovir in immune checkpoint inhibitor-refractory non-small cell lung cancer.

This phase 2a clinical trial evaluated the combination of aglatimagene besadenovec and valacyclovir in 76 patients with immune checkpoint inhibitor-refractory non-small cell lung cancer.

J Immunother CancerSep 28, 2026Read summary
Clinical ResearchOtolaryngology (ENT)

Non-usage rates after paediatric cochlear implantation: A systematic review and meta-analysis.

This systematic review and meta-analysis examined long-term cochlear implant use among paediatric recipients, synthesising 29 studies involving 2,595 children.

Int J Pediatr OtorhinolaryngolSep 28, 2026Read summary
Clinical ResearchMedical Genetics

Efficacy and safety of garetosmab, an activin A-blocking antibody, in fibrodysplasia ossificans progressiva (OPTIMA): a randomised, double-blind, placebo-controlled, phase 3 trial.

OPTIMA was a multicentre, randomised, double-blind, placebo-controlled phase 3 trial assessing monthly intravenous garetosmab in adults with fibrodysplasia ossificans progressiva.

LancetSep 28, 2026Read summary
Clinical ResearchUrologyOpen access

Changes in renal function in patients with chronic kidney disease after ureteroscopy: a systematic review and meta-analysis from EAU endourology.

This systematic review and meta-analysis evaluated changes in estimated glomerular filtration rate (eGFR) after ureteroscopy (URS) or retrograde intrarenal surgery (RIRS) in patients with chronic kidney disease (CKD).

UrolithiasisSep 28, 2026Read summary
Clinical ResearchUrologyOpen access

Vibegron, mirabegron, and other add-on therapies for persistent overactive bladder symptoms in α1-blocker-treated men with benign prostatic hyperplasia: a systematic review and Bayesian network meta-analysis.

This systematic review and Bayesian network meta-analysis evaluated the efficacy and safety of vibegron, mirabegron, and other add-on therapies for overactive bladder symptoms in men with benign prostatic hyperplasia…

World J UrolSep 28, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Second-Line Systemic Therapy Following First-Line FOLFIRINOX or NALIRIFOX in Metastatic Pancreatic Ductal Adenocarcinoma: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated second-line therapies following first-line FOLFIRINOX or NALIRIFOX in 3888 adults with metastatic pancreatic ductal adenocarcinoma.

J Gastrointest CancerSep 28, 2026Read summary
Case ReportGeneral Surgery

Jejunal transection caused by postoperative adhesive small bowel obstruction: managed simultaneously with abdominal aortic aneurysm.

A man in his 90s presented with abdominal pain, diagnosed with postoperative adhesive small bowel obstruction and an abdominal aortic aneurysm (AAA).

BMJ Case RepSep 28, 2026Read case
Clinical ResearchNeurology

Evaluating the Clinical Utility of TSPO-PET in MS and the Influence of Methodological Heterogeneity: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated TSPO-PET imaging in multiple sclerosis (MS) patients compared to healthy controls.

Neurol Neuroimmunol NeuroinflammSep 28, 2026Read summary
Case ReportNeurology

Coexisting Postural Orthostatic Tachycardia Syndrome on Autonomic Reflex Testing in Functional Neurologic Disorder.

An 18-year-old woman with a prior diagnosis of functional neurological disorder (FND) presented with fluctuating lower-extremity weakness, gait disturbance, and recurrent drop attacks, alongside persistent orthostatic…

Am J Case RepSep 28, 2026Read case
Clinical ResearchNeurology

Association between insular involvement and ECG abnormalities in ischemic stroke: a systematic review and meta-analysis.

This systematic review and meta-analysis examined whether insular involvement in ischemic stroke is associated with ECG abnormalities, using cohort and cross-sectional studies comparing patients with and without insular…

J Clin NeurosciSep 28, 2026Read summary
Clinical ResearchUrology

Escherichia coli Nissle 1917 for the prevention of recurrent uncomplicated urinary tract infections in women: a pilot randomized placebo-controlled trial.

This pilot multicenter randomized controlled trial evaluated the efficacy of Escherichia coli Nissle 1917 (EcN) in preventing recurrent uncomplicated urinary tract infections (rUTIs) in 50 women.

Arch Ital Urol AndrolSep 28, 2026Read summary
Case ReportNephrology

Phytate and L-methionine for preventing recurrence of infection renal stones.

This report details a series of cases where patients with recurrent infection renal stones and brushite stones were treated with a combination of phytate and L-methionine.

Arch Ital Urol AndrolSep 28, 2026Read case
Clinical ResearchPediatrics

Effects of Teleintervention Maintenance Programs for Children (Age 6-12) and Adolescents (Age 13-18) With Overweight or Obesity-Promoting a Healthy Lifestyle: A Systematic Review.

This systematic review evaluated teleintervention maintenance programs for children (ages 6-12) and adolescents (ages 13-18) with overweight or obesity.

Pediatr ObesSep 28, 2026Read summary
Clinical ResearchPediatrics

Adherence to the Mediterranean Diet Is Associated With a Lower Risk of Obesity in Children Under 18 Years: A Comprehensive Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined the relationship between adherence to the Mediterranean Diet (MedDiet) and obesity risk in children and adolescents.

Pediatr ObesSep 28, 2026Read summary
Clinical ResearchNephrology

Effectiveness and Safety of Virtual Reality Interventions for Symptom Management in Adults Undergoing Hemodialysis: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This systematic review and meta-analysis evaluated the effectiveness and safety of virtual reality (VR) interventions for symptom management in adults undergoing hemodialysis.

J Med Internet ResSep 28, 2026Read summary
Clinical ResearchUrology

Efficacy and safety of α1-adrenergic receptor antagonists in managing acute urinary retention secondary to benign prostatic hyperplasia: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis evaluated the efficacy of α1-adrenergic receptor antagonists in managing acute urinary retention (AUR) due to benign prostatic hyperplasia (BPH).

Arch Ital Urol AndrolSep 28, 2026Read summary
Clinical ResearchCardiology

Effectiveness of elastic therapeutic taping in pain management after median sternotomy: A randomized controlled trial.

This randomized controlled trial evaluated the effectiveness of elastic therapeutic taping on postoperative pain and recovery in 195 patients undergoing coronary artery bypass grafting via median sternotomy.

PLoS OneSep 28, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Non-thyroidal illness syndrome and isolated low triiodothyronine as prognostic markers in acute illness: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the relationship between thyroid hormone alterations and mortality in critically ill and cardiovascular patients.

EndocrineSep 28, 2026Read summary
Case ReportPathology (Anatomic & Clinical)

Primary renal glomus tumours of uncertain malignant potential: diagnostic challenges and insights from two instances.

Two elderly patients presented with abdominal pain and were found to have large renal masses on imaging. Both underwent nephrectomy, and histopathological analysis revealed glomus tumors with atypical features but not…

BMJ Case RepSep 28, 2026Read case
Clinical ResearchUrologyOpen access

Intraoperative positioning strategies to improve stone-free outcomes during retrograde intrarenal surgery: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the impact of intraoperative positioning strategies on stone-free outcomes during retrograde intrarenal surgery (RIRS) for renal calculi, involving 998 patients across…

World J UrolSep 28, 2026Read summary
Clinical ResearchOncology (Medical)Open access

A comparison of the efficacy of cognitive-behavioral stress management and acceptance and commitment therapy on the quality of life and fatigue of caregivers of patients with cancer: a randomized controlled trial.

This randomized controlled trial compared the efficacy of cognitive behavioral stress management (CBSM) and acceptance and commitment therapy (ACT) on the quality of life and fatigue in 66 caregivers of cancer patients.

Support Care CancerSep 28, 2026Read summary
Clinical ResearchMedical Genetics

Effect of prenatal genetic counseling on anxiety and test attitudes in pregnant women: a randomized trial.

This randomized controlled trial assessed the impact of prenatal genetic counseling on anxiety and attitudes towards prenatal diagnostic tests in 66 pregnant women.

Rev Esc Enferm USPSep 28, 2026Read summary
Clinical ResearchGeriatrics

A study protocol evaluating the effectiveness of the older adult's digital health literacy (ODDHeaL) intervention.

This randomized controlled trial evaluates the effectiveness of the Older Adults Digital Health Literacy (ODDHeaL) intervention in improving digital health literacy among community-dwelling adults aged 55 and older.

PLoS OneSep 28, 2026Read summary

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