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1891 articles
March 202611
Medication-related osteonecrosis of the jaw with severe soft tissue necrosis associated with osimertinib therapy.
A 73-year-old woman receiving osimertinib for recurrent lung adenocarcinoma developed exposed jaw bone and buccal mucosal necrosis.
What is the incidence and clinical significance of dry eye disease in patients treated with immune checkpoint inhibitors? A systematic review and meta-analysis of ocular immune-related adverse events.
This systematic review and meta-analysis assessed dry eye disease (DED) in adults treated with immune checkpoint inhibitors (ICIs), drawing on 13 studies.
Prognostic value of albumin-bilirubin grade in patients with pancreatic cancer: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed whether albumin-bilirubin (ALBI) grade is associated with outcomes in patients with pancreatic cancer.
Comparison of Computed Tomography Ventilation Imaging and Hyperpolarized 3 He Magnetic Resonance Imaging in Patients With Lung Cancer.
This phase 2 comparative study assessed computed tomography ventilation imaging (CTVI) against hyperpolarized 3He MRI in 27 patients with non-small cell lung cancer undergoing functional-avoidance radiotherapy.
Natural history of untreated prostate cancer: a comprehensive review of long-term progression patterns and survival outcomes.
This systematic review synthesized long-term outcomes in untreated or conservatively managed prostate cancer, drawing on 15 studies and 43,127 patients with median follow-up of 15–30 years.
Epcoritamab plus rituximab, dexamethasone, cytarabine, oxaliplatin/carboplatin induces deep and durable responses in transplant-eligible patients with relapsed or refractory diffuse large B-cell lymphoma: results from the EPCORE NHL-2 trial.
Arm 4 of the multicenter phase IB/II EPCORE NHL-2 trial evaluated epcoritamab plus R-DHAX/C in transplant-eligible patients with CD20-positive relapsed or refractory diffuse large B-cell lymphoma.
Phase II Clinical Study of Adebrelimab and Bevacizumab Combined With Cisplatin/Carboplatin in Patients With Triple-Negative Breast Cancer With Brain Metastases (ABC Study).
This phase II clinical trial evaluated adebrelimab, bevacizumab, and cisplatin or carboplatin in 35 patients with triple-negative breast cancer and active brain metastases.
Acute Promyelocytic Leukemia with t(11;17)(q23.2;q21.2) Treated with Haploidentical Transplantation Using Post-transplant Cyclophosphamide.
A 55-year-old man presented with acute promyelocytic leukemia (APL), diagnosed from its distinctive morphology. Subsequent cytogenetic testing identified t(11;17)(q23.2;q21.2), suggesting a ZBTB16::RARA fusion.
IgA Vasculitis Developing during Trastuzumab Emtansine Therapy for HER2-positive Breast Cancer.
An elderly woman receiving trastuzumab emtansine (T-DM1) for HER2-positive breast cancer developed purpura, hematuria, proteinuria, and reduced renal function.
Post-transplant cyclophosphamide as graft-versus-host disease prophylaxis for matched related donor hematopoietic stem cell transplantation in acute leukemia: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed post-transplant cyclophosphamide (PTCy) for graft-versus-host disease (GVHD) prophylaxis in patients with acute leukemia undergoing matched related donor hematopoietic…
18F-Fluciclovine (18F-FACBC) PET/MRI Findings in Tumefactive Demyelinating Lesion: A Case Report.
A 28-year-old man presented with acute dysarthria and right facial droop. MRI showed a horseshoe-shaped left frontal mass, initially suspected to be a tumefactive demyelinating lesion (TDL).
February 202613
A case report on αIN antibody-mediated paraneoplastic cerebellar ataxia.
A 68-year-old woman developed subacute blurred vision, leg weakness, and dysarthria after SARS-CoV-2 infection. Examination showed nystagmus, dysarthria, and limb ataxia.
Efficacy and safety of Ruxolitinib-based combination therapy in the patients with Myelofibrosis (MF): a systematic review and meta-analysis.
This systematic review and meta-analysis assessed the efficacy and safety of 13 ruxolitinib-based combination regimens for myelofibrosis, using 19 studies involving 1,088 patients.
Serious adverse events following human papillomavirus vaccination: A systematic review and meta-analysis of post-marketing evidence.
This systematic review and meta-analysis assessed serious adverse events (SAEs) reported after human papillomavirus vaccination in post-licensure observational studies and surveillance.
Prognostic implications of myelodysplasia-related gene mutations in NPM1 -mutated acute myeloid leukemia: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed whether myelodysplasia-related gene (MRG) mutations affect prognosis in NPM1-mutated acute myeloid leukemia.
A mixed inflammatory peripheral signature defines clinical outcomes in a phase II trial combining pembrolizumab with paclitaxel and carboplatin in melanoma.
This multicenter phase II trial evaluated pembrolizumab plus carboplatin/paclitaxel (CP) in 30 patients with unresectable or metastatic melanoma who had not received prior immunotherapy.
"Et tu, Brute?" - A Case of Ixazomib - Induced Cancer Therapy-related Cardiac Dysfunction.
An 81-year-old man with multiple myeloma presented with decompensated heart failure. His left ventricular ejection fraction (LVEF) had been preserved at baseline but fell to 35% 13 months after starting ixazomib.
Hepatocellular Carcinoma Associated with Hepatic Sarcoidosis and Budd-Chiari Syndrome: A Case Report and Review of the Literature.
A 71-year-old woman with cutaneous sarcoidosis presented with hepatocellular carcinoma. Evaluation identified Budd-Chiari syndrome, indicating hepatic venous outflow obstruction, and hepatic granulomas with advanced…
An Effective Case of Radiofrequency Ablation with the Combination of Durvalumab and Tremelimumab Treatment for Hepatocellular Carcinoma.
A 77-year-old man with advanced hepatocellular carcinoma received durvalumab plus tremelimumab. Imaging showed tumor shrinkage and serum tumor markers normalized, but contrast-enhanced ultrasound detected residual…
Immune-mediated Myocarditis after Durvalumab/tremelimumab Treatment for Unresectable Hepatocellular Carcinoma.
A man with unresectable hepatocellular carcinoma developed syncope three weeks after treatment with durvalumab and tremelimumab.
Secondary poor graft function after autologous stem cell transplantation in multiple myeloma: a case-based expert review and successful rescue with secondary autologous stem cell infusion.
A 59-year-old woman with IgG κ multiple myeloma initially achieved neutrophil and platelet engraftment after autologous hematopoietic stem-cell transplantation, but later developed recurrent transfusion-dependent…
Molecular targeted therapy in combination with chemotherapy for the treatment of platinum-resistant/refractory ovarian cancer (PROC): a systematic review and network meta-analysis.
This Bayesian network meta-analysis compared molecular targeted agents combined with chemotherapy against chemotherapy alone for platinum-resistant or refractory ovarian cancer (PROC).
A Phase 1 Study of Neoadjuvant Cabozantinib in Combination With Radiation Therapy for Sarcomas of the Extremities.
This phase 1 trial evaluated the safety and dose of neoadjuvant cabozantinib given concurrently with radiation therapy before surgery in adults with newly diagnosed, localized extremity soft tissue sarcoma.
Economic burden of advanced non-small cell lung cancer (NSCLC): a systematic literature review.
This systematic literature review examined healthcare use and costs among patients with locally advanced or metastatic NSCLC, drawing on 50 publications covering 43 studies published from 2011 onwards.
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