Trending archive
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1891 articles
December 20258
Central Venous Access Device Complications in Children With Leukemia: A Systematic Review and Meta-Analysis.
This systematic review and random-effects meta-analysis assessed central venous access device (CVAD) complications in children aged 18 years or younger receiving treatment for leukemia.
Comparative incidence of peripheral neuropathy associated with taxane chemotherapy in patients with breast cancer: A network meta-analysis.
This Bayesian network meta-analysis compared taxane-associated peripheral neuropathy in females with breast cancer. It included 27 studies and 12,101 patients, assessing docetaxel, cabazitaxel, nab-paclitaxel, liposomal…
Hepatocellular carcinoma with macrovascular invasion: Review and survival meta-analysis of initial local therapy using minimal prognostic criteria.
This PRISMA-guided systematic review and meta-analysis assessed overall survival after initial local therapies, rather than systemic therapy, for hepatocellular carcinoma with macrovascular invasion.
Artificial Intelligence (AI)-based tools in the diagnosis and management of prostate cancer: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed AI tools for prostate cancer diagnosis, prognosis, and management, drawing on studies published from January 2020 to April 2025.
Three-Month Functional Exercise Reduces Upper Limb Lymphedema after Breast Cancer Surgery: A Prospective Randomized Controlled Trial.
This prospective randomized controlled trial evaluated a 3-month combined rehabilitation exercise program in 120 patients after breast cancer surgery.
Efficacy and safety of treatments for metastatic castration-sensitive prostate cancer: A comprehensive network meta-analysis including final ARANOTE data.
This network meta-analysis compared efficacy and safety of treatment combinations for metastatic castration-sensitive prostate cancer, incorporating final ARANOTE trial data.
Efficacy and safety of trastuzumab deruxtecan in HER2-high and HER2-low breast cancer: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and random-effects meta-analysis pooled four randomized controlled trials involving 2,555 patients with HER2-high or HER2-low breast cancer to assess trastuzumab deruxtecan (T-DXd) against control…
Stool-based methylated syndecan-2 test and fecal immunochemical test for advanced colorectal neoplasia screening in the Chinese population: A multicenter randomized noncomparative study.
This multicenter randomized noncomparative study assessed stool-based methylated Syndecan-2 (mSDC2) testing versus fecal immunochemical testing (FIT) for advanced colorectal neoplasia screening among Chinese adults aged…
November 202512
The interplay between autophagy, p16 INK4a , and senescence in tumor cells: a systematic review.
This systematic review examined how autophagy and p16INK4a interact with cellular senescence in tumor cells. A search of three databases identified 10 eligible studies published between January 2000 and April 2025.
Diagnostic Dilemma and Management of a Rapidly Enlarging Thigh Mass: A Case Report of Fibromatosis Mimicking Soft-tissue Sarcoma.
A 27-year-old woman presented with a painless, firm, immobile left-thigh mass that enlarged from 2 cm × 2 cm to 10 cm × 10 cm over 9 months. MRI of the thigh and pelvis suggested soft-tissue sarcoma.
Molecular and Immunohistochemical Characteristics of Primary Vaginal Leiomyosarcoma: Case Report and Review of the Literature.
A 46-year-old patient had a primary leiomyosarcoma arising in the vaginal wall, with no uterine or cervical involvement. The tumor comprised atypical spindle cells and showed tumor-type necrosis and 25 mitotic figures…
Preoperative mFOLFIRINOX versus PAXG for stage I-III resectable and borderline resectable pancreatic ductal adenocarcinoma (PACT-21 CASSANDRA): results of the first randomisation analysis of a randomised, open-label, 2 × 2 factorial phase 3 trial.
The CASSANDRA randomised, open-label, phase 3 trial compared preoperative PAXG with mFOLFIRINOX in adults with resectable or borderline resectable pancreatic ductal adenocarcinoma at 17 Italian academic hospitals.
Regorafenib in adult patients with recurrent glioblastoma: a single-arm meta-analysis.
This systematic review and single-arm meta-analysis pooled outcomes from ten studies of regorafenib in 724 adults with recurrent glioblastoma.
The role of the human microbiome in prostate cancer: a systematic review from diagnosis to treatment.
This systematic review assessed human microbiome associations with prostate cancer (PC) diagnosis, prognosis, and treatment response.
Quality of Life in Breast and Gynecological Cancer: A Review of Systematic Reviews, 1985-2025.
This review of systematic reviews synthesized research on quality of life (QoL) among people with breast and gynecological cancers, covering publications from 1985 to 2025.
Efficacy and safety of allogeneic CD19 CAR NK-cell therapy in systemic lupus erythematosus: a case series in China.
Lately, autologous CD19-targeting chimeric antigen receptor (CAR) T cells have shown excellent efficacy in treatment of autoimmune diseases, but with great safety concerns, such as infections.
Neonatal Cardiac Tamponade Caused by a Pericardial Tufted Angioma: A Rare Cause of Fetal Pericardial Effusion and a Multidisciplinary Treatment Approach.
A term neonate with prenatal pericardial effusion developed recurrent cardiac tamponade despite drainage and medical therapy.
Intranasal Ketamine for Episodic Neuropathic Pain in a Cancer Patient: A Case Report.
A 49-year-old patient with metastatic lung adenocarcinoma presented to an outpatient palliative care clinic with severe, uncontrolled episodic neuropathic pain in the lower extremity.
Weight Loss, Obesity Medication, and Risk of Obesity-Associated Cancer: A Meta-Analysis of Randomized Controlled Trials.
This meta-analysis of randomized controlled trials assessed whether antiobesity medications (AOMs) and medication-mediated weight loss were associated with obesity-associated cancer risk in people with overweight or…
Furmonertinib activity in NSCLC Harbouring EGFR L858R and ERBB2 S310F co-mutations: a case report with literature review.
A 61-year-old woman with advanced lung adenocarcinoma had concurrent EGFR L858R (exon 21) and ERBB2 S310F mutations identified by next-generation sequencing.
October 20254
Spontaneous Remission and Subsequent Relapse in Pediatric Acute Myeloid Leukemia (AML-M5): A Case Report and Literature Review.
A child with acute myeloid leukemia, French-American-British subtype M5 (AML-M5), experienced spontaneous remission after receiving blood transfusions and anti-infective therapy, without leukemia-specific treatment.
Collision Tumor of the Uterine Corpus: Primary EBV-positive Diffuse Large B-Cell Lymphoma and Endometrioid Carcinoma.
A 63-year-old postmenopausal woman presented with vaginal bleeding, and ultrasonography showed a 2.3×1.0 cm mildly hyperechoic uterine corpus mass.
Immune Checkpoint Inhibitor Mediated Keratitis: A Case Study.
A 73-year-old man with metastatic squamous cell carcinoma of the tongue developed keratitis attributed to pembrolizumab, an immune checkpoint inhibitor.
HPV42 - a human papillomavirus classified as a low-risk type with oncogenic potential.
The report describes HPV42 detection across anogenital warts, digital squamous cell carcinoma in situ, and a lymphogenously metastasized digital papillary adenocarcinoma (DPA).
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