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785 articles
September 202624
Factors associated with unplanned re-admission after elective gastroenterological surgery: an analysis of 1824 participants with clean-contaminated wounds enrolled in two randomized controlled trials for the prevention of surgical site infection.
This analysis examined factors associated with unplanned readmission within 30 days of discharge among patients undergoing elective gastroenterological surgery with clean-contaminated wounds.
The Optimal Therapeutic Window for Nonbioartificial Liver Support in Acute-On-Chronic Liver Failure: A Meta-Analysis and Meta-Regression Based on Baseline MELD Score.
This meta-analysis evaluated the efficacy of nonbioartificial liver support (NBALS) in patients with acute-on-chronic liver failure (ACLF), focusing on baseline MELD scores.
Pancreatic fat and the risk of future dysglycemia: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the association between pancreatic fat and future dysglycemic outcomes, including type 2 diabetes (T2D) and glycemic progression.
Conserved hepatic RNA signatures across multiple cohorts reveal novel mechanistic clues for advanced fibrosis in human MASLD.
This meta-analysis examined hepatic transcriptomic data from approximately 1000 patients with metabolic dysfunction-associated steatotic liver disease (MASLD) to identify mechanisms of fibrosis progression.
Postoperative ctDNA-Guided Adjuvant Therapy in Resected Colorectal Cancer: A Systematic Review and Meta-analysis of Prognostic Validity Versus Treatment-Decision Utility.
This systematic review and meta-analysis evaluated the prognostic validity and treatment-decision utility of postoperative circulating tumor DNA (ctDNA) in resected colorectal cancer.
Machine learning identifies microbiome and clinical predictors of sustained weight loss following prolonged fasting.
This randomized controlled trial investigated the effects of a 5-day fasting intervention on body composition and gut microbiome in 38 healthy adults, with follow-up at 12 weeks.
Induction FLOT Chemotherapy Prior to Neoadjuvant Chemoradiotherapy in the Treatment of Lower Esophageal and Proximal Gastric Adenocarcinoma: A Phase II, Single-Arm Clinical Trial.
This Phase II, single-arm clinical trial evaluated the effectiveness of induction FLOT chemotherapy followed by neoadjuvant chemoradiotherapy in patients with resectable distal esophageal and proximal gastric…
Fourteen-Day Amoxicillin- or Tetracycline-Containing Bismuth Quadruple Therapy versus 14-Day Metronidazole-Based Triple Therapy as the Treatment for Clarithromycin-Resistant Helicobacter pylori Infection: A Multicenter Randomized Controlled Trial.
This multicenter randomized controlled trial evaluated the efficacy of bismuth-containing quadruple therapy (PAM-B) versus standard PAM and PBMT for treating clarithromycin-resistant Helicobacter pylori infections in…
Atraumatic Knee Marrow Edema-Like Signal Preceding a Low-Energy Bicondylar Tibial Plateau Fracture in a Patient with Crohn Disease: A Case Report.
A 44-year-old man with Crohn disease and a history of corticosteroid use presented with atraumatic, load-related right knee pain.
A prospective randomized controlled pilot study of gut microbiome modulation by Nigella sativa seed oil and thymoquinone metabolism in healthy volunteers: implications for gastrointestinal surgery.
This prospective randomized controlled pilot study investigated the effects of Nigella sativa seed oil (NSSO) on gut microbiome modulation in eight healthy adults.
Efficacy and safety of orforglipron 12 mg versus orforglipron 36 mg maintenance dose among patients with obesity with or without diabetes: a systematic review and comprehensive meta-analysis.
This systematic review and meta-analysis evaluated the efficacy and safety of orforglipron 12 mg versus 36 mg in 3459 obese adults, with or without diabetes.
Enteric NK/T Cell Lymphoma-induced Recurrent Perforation in the Intestine: A Case Report.
A 31-year-old female presented with abdominal pain and fever, following a previous jejunal perforation diagnosed as an EBV-associated lymphoproliferative disorder.
Comparative Outcomes of Single-Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy Versus Roux-en-Y Gastric Bypass in Adults with Severe Obesity: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis compared single-anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) and Roux-en-Y gastric bypass (RYGB) in adults with severe obesity.
Efficacy and safety of avexitide for treatment of hypoglycemia following bariatric and other upper gastrointestinal surgeries: a phase 2b study.
This phase 2b randomised controlled study evaluated avexitide in adults with clinically important hypoglycemia after Roux-en-Y gastric bypass, sleeve gastrectomy, total gastrectomy, or Nissen fundoplication.
Major cardiovascular event risk of advanced therapies in inflammatory bowel diseases: systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the risk of major adverse cardiovascular events (MACE) associated with advanced therapies in patients with inflammatory bowel disease (IBD).
Small Intestinal Cavernous Hemangioma Presenting with Recurrent Gastrointestinal Bleeding: A Case Report and Narrative Review.
A 74-year-old female experienced recurrent melena for five months, with initial imaging failing to identify a bleeding source.
Chronic hypophosphatemia leading to the diagnosis of autosomal recessive hypophosphatemic rickets type 2 caused by a novel pathogenic variant in ENPP1.
Two brothers in their late 40s presented with chronic hypophosphatemia and elevated serum parathyroid hormone (PTH) levels.
A case report of acute liver failure caused by Gyromitra venenata poisoning and a literature review.
A patient in Guizhou Province, China, developed illness after eating approximately 500 grams of self-gathered wild mushrooms.
First-line fecal microbiota transplantation for the management of immune checkpoint inhibitor-mediated diarrhea and colitis.
This preliminary clinical trial evaluated first-line fecal microbiota transplantation (FMT) for immune checkpoint inhibitor-mediated diarrhea and colitis (IMDC), using multi-omics profiling.
A 7-mm Covered TIPS Reduces Hepatic Encephalopathy Without Increasing Rebleeding in Cirrhotic Patients With Small Liver: A Randomized Study.
This multicenter randomized controlled trial evaluated the efficacy of 7-mm covered transjugular intrahepatic portosystemic shunts (TIPS) compared to 8-mm stents in cirrhotic patients with small livers.
Early Analgesia for the Management of Acute Pancreatitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This systematic review and meta-analysis evaluated the efficacy and safety of early analgesic interventions, specifically comparing NSAIDs to opioids, in adults with acute pancreatitis (AP).
Efficacy and Safety of Pancreatoscopy-Guided Laser Lithotripsy Versus Electrohydraulic Lithotripsy in Managing Pancreatic Duct Stone: A System Review and Meta-Analysis.
This meta-analysis compared the efficacy and safety of pancreatoscopy-guided laser lithotripsy (LL) and electrohydraulic lithotripsy (EHL) in treating refractory pancreatic duct stones in 326 patients.
Protein sorting and proteostasis mechanisms in CFTR-related exocrine pancreas dysfunction: A systematic narrative review.
This systematic narrative review examines the role of protein sorting mechanisms in CFTR-related exocrine pancreatic dysfunction.
Comparative effectiveness and safety of robotic versus laparoscopic liver resection for benign liver diseases: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effectiveness and safety of robotic liver resection (RLR) versus laparoscopic liver resection (LLR) for benign liver diseases, analyzing data from nine…
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