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1022 articles
September 202624
Clinical Reasoning: A 60-Year-Old Woman With Fever, Headache, Diplopia, and Unilateral Periorbital Swelling.
A 60-year-old woman presented with fever, headache, horizontal diplopia, and unilateral periorbital swelling after experiencing recurrent gingival swelling and pain for about a month.
POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder and skin changes) associated with Castleman disease and latent tuberculosis: a diagnostic challenge.
A woman in her 40s presented with progressive multisystem disease, including chronic distal neuropathy, constitutional decline, lymphadenopathy, and serosal effusions.
Performing lifestyle changes and reducing stroke risk: a process evaluation of a stroke prevention intervention.
This randomized controlled trial evaluated a stroke prevention intervention in Swedish primary healthcare, focusing on implementation processes and mechanisms of change among 122 high-risk participants.
Non-paraneoplastic Autoimmune Cerebellar Ataxia with Sensory Ataxia Associated with the Anti-Ca/ARHGAP26 Antibody: A Case Report.
A man in his 50s presented with one month of subacute, progressive gait instability, exhibiting both cerebellar and deep-sensory ataxia.
Thalamic Tuberculoma Presenting as Isolated Gait Disturbance Without Systemic or Meningeal Symptoms in a 2-Year-Old Child: A Case Report.
A 2-year-old boy presented with isolated gait disturbance and decreased power on the left side, without systemic or meningeal symptoms.
Neurosyphilis Concurrently Presenting With Limbic Encephalitis and Normal Pressure Hydrocephalus: A Case Report.
A 47-year-old man presented with cognitive decline, gait disturbance, and urinary incontinence. Imaging revealed ventricular enlargement and high signal intensity in the medial temporal lobes.
Continuous Versus Routine EEG in Critically Ill Patients Without Primary Neurologic Condition: Analysis of a Randomized Controlled Trial.
This post hoc analysis of the multicenter randomized CERTA trial evaluated the effectiveness of continuous EEG (cEEG) versus routine EEG (rEEG) in critically ill patients without primary neurologic conditions.
A rare case of hereditary spastic paraplegia with homozygous mutation in the ZFYVE26 gene.
A 19-year-old female with consanguineous parents presented with gait disturbances, lower limb spasticity, and dysarthria. Neurological examination revealed motor and mental retardation, bilateral lower limb spasticity…
Lumbar spinal brucellosis presenting as an atypical epidural abscess.
A man in his 50s presented with low back pain and lower limb radiculopathy. MRI revealed a ventral epidural collection at L4-L5, resembling a sequestered disc fragment, without significant vertebral or disc involvement.
Severe neurodevelopmental phenotype with multisystem involvement in VPS16-related mucopolysaccharidosis-like syndrome.
A patient with biallelic VPS16 variants presented with profound developmental delay, early-onset epilepsy, and spasticity, alongside multisystem issues such as recurrent infections and neutropenia.
Scleromyxedema-Associated Myopathy and Vacuolar Myopathy with Monoclonal Gammopathy and Stiffness (VAMMGAS) as manifestations of Monoclonal Gammopathy of Clinical Significance (MGCS): a disease spectrum between autophagy dysfunction and inflammation.
This report discusses two patients with Scleromyxedema-Associated Myopathy (SAM) and one with Vacuolar Myopathy with Monoclonal Gammopathy and Stiffness (VAMMGAS), both associated with Monoclonal Gammopathy of Clinical…
The effects of dual-task training with different task priorities on physical performance and cognitive status in patients with Parkinson's disease: a single-blind, randomized controlled trial.
This randomized controlled trial investigated the effects of variable-priority dual-task training (V-DTT) and fixed-priority dual-task training (F-DTT) on physical performance and cognitive status in 30 patients with…
Stroke mimic caused by severe hypomagnesemia: a case report and literature review.
A patient with a history of transient neurological deficits presented with stroke-like symptoms, including hemiparesis and aphasia. The patient was on Proton Pump Inhibitors and Metformin.
Efficacy of transcranial alternating current stimulation on cognitive function in patients with dementia: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis evaluated the efficacy of transcranial alternating current stimulation (tACS) on cognitive function in 357 dementia patients across 9 randomized controlled trials.
Systolic blood pressure targets after successful endovascular thrombectomy: a network meta-analysis of randomized controlled trials.
This network meta-analysis evaluated the impact of different systolic blood pressure (SBP) targets on outcomes after endovascular thrombectomy in eight studies.
Prevalence of Cerebellar Cognitive Affective Syndrome in Patients with Cerebellar Disorders: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the prevalence of cerebellar cognitive affective syndrome (CCAS) in patients with cerebellar disorders.
Lacosamide effects on pain management in patients with multiple sclerosis: A randomized, double-blind, placebo-controlled clinical trial.
This randomized, double-blind, placebo-controlled trial assessed lacosamide for moderate-to-severe MS-related pain in adults with definite multiple sclerosis.
Coexisting Postural Orthostatic Tachycardia Syndrome on Autonomic Reflex Testing in Functional Neurologic Disorder.
An 18-year-old woman with a prior diagnosis of functional neurological disorder (FND) presented with fluctuating lower-extremity weakness, gait disturbance, and recurrent drop attacks, alongside persistent orthostatic…
Intravenous thrombolysis use before interhospital transfer for thrombectomy: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the impact of intravenous thrombolysis (IVT) before interhospital transfer for endovascular thrombectomy (EVT) in patients with large-vessel occlusion acute ischemic…
Evaluating the Clinical Utility of TSPO-PET in MS and the Influence of Methodological Heterogeneity: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated TSPO-PET imaging in multiple sclerosis (MS) patients compared to healthy controls.
Ventral Cervical Spinal Schwannoma Presenting as Progressive Myelopathy.
A male in his 20s presented with a two-year history of progressive paraparesis and urinary incontinence. Neurological examination revealed signs of spasticity and reduced lower-limb power.
Autologous Hematopoietic Transplantation Reduces Brain Inflammatory and Axoglial Damage Biomarkers in Multiple Sclerosis.
This Phase II multicenter clinical trial investigated the effects of autologous hematopoietic stem cell transplantation (AHSCT) on inflammatory and axoglial damage biomarkers in 24 patients with severe multiple…
Acrodynia and CASPR2 Autoimmunity in Elemental Mercury Toxicity.
A 2-year-old girl presented with cough, congestion, and later developed sweating, fussiness, and a pruritic rash after exposure to elemental mercury from a household spill.
Endovascular Treatment for Patients Aged ≥80 Years with Large Ischemic Stroke.
This randomized controlled trial evaluated the effectiveness and safety of endovascular treatment (EVT) in patients aged ≥80 years with large ischemic stroke.
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