Trending archive
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434 articles
August 202623
Symptom burden to characterise, predict, and prevent asthma attacks: a patient-level meta-analysis of randomised trials and translational prospective studies.
This patient-level meta-analysis evaluated the prognostic value of symptom burden, measured by the ACQ-5, in predicting severe asthma attacks among 7161 participants from various studies.
Elastic tape as an add-on strategy to potentiate pulmonary rehabilitation outcomes in nonobese males with moderate-to-very severe COPD: A randomised clinical trial.
This randomized controlled trial evaluated the effects of elastic tape (ET) as an adjunct to pulmonary rehabilitation (PR) in 42 nonobese men with moderate-to-very severe COPD.
Comparative Efficacy, Safety, and Cost of Different Intrapleural Fibrinolytic Agents for the Management of Empyema Thoracis in Children: A Systematic Review.
This systematic review aimed to evaluate the efficacy, safety, and cost of intrapleural fibrinolytic agents for pediatric empyema thoracis.
Toward a standardized framework for chronic obstructive pulmonary disease self-care: An umbrella review.
This umbrella review synthesized international COPD guidelines and systematic reviews to define core components of COPD self-care and assess their alignment with guidance.
Diagnostic performance of machine learning models for malignant and non-malignant pleural effusion: Systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the diagnostic performance of machine learning models in distinguishing malignant pleural effusion (MPE) from non-malignant pleural effusion.
A lidocaine dry powder inhaler to modulate cough: particle engineering and human proof-of-concept.
This randomized controlled trial investigated a lidocaine dry powder inhaler formulation designed for targeting cough receptors in the upper and central airways.
Does a clinical assessment of upper airway obstruction in robin sequence correspond to sleep study results?
This randomized controlled trial assessed the correlation between clinical evaluations of obstructive sleep apnea (OSA) severity and sleep study results in 29 infants with Robin sequence.
An acceptance-based healthy lifestyle programme for community-dwelling patients with pneumoconiosis: A waitlist pilot randomised controlled trial.
This multicenter, pilot randomized controlled trial evaluated a 6-week acceptance-based healthy lifestyle program for community-dwelling patients with pneumoconiosis.
Daily low-dose carboplatin or weekly carboplatin plus nab-paclitaxel for concurrent chemoradiotherapy in older patients with locally advanced non-small cell lung cancer (JCOG1914): A randomized phase 3 trial.
This randomized phase 3 trial evaluated daily low-dose carboplatin versus weekly carboplatin plus nab-paclitaxel in patients aged ≥75 years with locally advanced non-small cell lung cancer (LA-NSCLC).
Patient-reported outcomes with tarlatamab in extensive-stage small cell lung cancer after platinum-based chemotherapy: results from the phase 3 DeLLphi-304 trial.
The phase 3 DeLLphi-304 trial evaluated patient-reported outcomes (PROs) in adults with extensive-stage small cell lung cancer (ES-SCLC) receiving tarlatamab versus standard-of-care chemotherapy after platinum-based…
A phase 2 study of encorafenib in combination with binimetinib for Chinese participants with BRAF V600E mutated metastatic non-small cell lung cancer: Results from the OCEAN II study.
The OCEAN II study, a phase 2 clinical trial, evaluated the efficacy and safety of encorafenib combined with binimetinib in 63 Chinese participants with BRAF V600E-mutated metastatic non-small cell lung cancer.
Symptoms and treatment response to florensocatib and inhaled tobramycin in bronchiectasis: Post hoc analysis of two randomized trials.
This post hoc analysis of two randomized trials (SAVE-BE and TORNASOL) evaluated the impact of baseline symptom burden on treatment responses to florensocatib and inhaled tobramycin in patients with bronchiectasis.
Single-slice Functional Lung MRI During Metronome-Paced Tachypnea Detects Changes in Regional Ventilation Dynamics After a Single Dose of Dual Bronchodilator Treatment in COPD.
This randomized controlled trial evaluated the effects of dual bronchodilator treatment on regional ventilation dynamics in patients with stable COPD using single-slice PREFUL MRI during metronome-paced tachypnea (MPT).
MicroRNAs in IPF and lung cancer: convergent and divergent mechanisms: a systematic review.
This systematic review examines the role of microRNAs (miRNAs) in idiopathic pulmonary fibrosis (IPF) and lung cancer (LC), highlighting shared and distinct mechanisms.
Fatal pulmonary thromboembolism associated with excessive nitrous oxide consumption over several weeks.
A man in his early twenties was hospitalized with acute nitrous oxide intoxication, vitamin B12 deficiency and anaemia. Two weeks later, he was found dead; empty nitrous oxide cartridges were present, and his mother…
Interventions with a significant mortality difference in acute respiratory distress syndrome: A systematic review and comparison with Guidelines.
This systematic review analyzed 33 randomized controlled trials (RCTs) to compare interventions with significant mortality differences in acute respiratory distress syndrome (ARDS) against European and American…
Stage shift, histological differentiation, and survival patterns of lung squamous cell carcinoma versus adenocarcinoma in low-dose CT screening.
This randomized controlled trial compared stage shift, histological differentiation, and survival patterns between lung squamous cell carcinoma (LUSC) and adenocarcinoma (LUAD) in low-dose CT (LDCT) screening.
Chronic Melioidosis Presenting with Pneumonia, Empyema, and Splenic Abscess.
A patient with recurrent chest pain, cough, and abdominal discomfort over 11 months had initially been treated for a common bacterial infection.
Diagnostic accuracy of bronchoalveolar lavage fluid-based testing for pulmonary cryptococcosis: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the diagnostic accuracy of bronchoalveolar lavage fluid (BALF)-based testing for pulmonary cryptococcosis.
Feedback-enhanced electronic monitoring for asthma inhaler adherence: A systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis of randomized controlled trials assessed feedback-enhanced electronic inhaler monitoring versus standard care in people with asthma.
Rethinking Muscle Wasting in Critical Illness: A Systematic Review and Meta-Analysis of Myofiber Size and Protein Turnover.
This systematic review and meta-analysis examined skeletal muscle dysfunction in adults with critical illness, analyzing myofiber size and protein turnover.
Focal Vascular Photopenia as a Metabolic Signature of Pulmonary Embolism on AI-Enhanced 18 F-FDG PET/CT.
Artificial intelligence (AI)-enhanced reconstruction of 18 F-FDG PET/CT may reveal important metabolic patterns barely visible on standard reconstructions.
Pulmonary Arterial Hypertension-Targeted Therapy for Pulmonary Hypertension Associated With Left Heart Disease: Bayesian and Frequentist Meta-Analysis of Randomized Controlled Trials.
This Bayesian and frequentist meta-analysis assessed pulmonary arterial hypertension (PAH)-targeted therapy versus placebo in patients with pulmonary hypertension associated with left heart disease (PH-LHD).
July 20261
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