FeaturedDermatology
Fractional CO₂ laser combined with intradermal and topical platelet-rich plasma for hypertrophic scars: a randomized controlled trial.
Lasers Med SciOct 23, 2026Open access
This prospective, randomized, assessor-blinded trial compared fractional CO₂ laser plus intradermal and topical platelet-rich plasma (PRP) with laser plus saline in 120 patients with hypertrophic scars.
Why it matters
The trial suggests that adding intradermal and topical PRP to fractional CO₂ laser can improve clinical scar scores beyond laser alone, providing evidence for PRP as a potential adjunct in hypertrophic-scar treatment.