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Targeting Fibroblast Activation Protein with [177Lu]Lu-FAP-2286 in Patients with Advanced Solid Tumors in the Phase I LuMIERE Trial.

Clin Cancer ResSep 1, 2026Open access

The Phase I LuMIERE trial evaluated the safety of [177Lu]Lu-FAP-2286 in 27 heavily pretreated patients with advanced solid tumors.

Why it matters

This study highlights the potential of targeting fibroblast activation protein in advanced solid tumors, providing a foundation for further investigation into the safety and efficacy of radiopharmaceutical therapies in…

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Clinical ResearchOncology (Medical)

Bone metastases in lung carcinoids: current challenges in diagnosis and treatment -A systematic review of an unexplored issue.

This systematic review examined bone metastases (BMs) in lung carcinoid patients, revealing an incidence of 17.2%. The study highlighted the challenges in diagnosis and treatment, noting that BMs were predominantly…

EndocrineSep 9, 2026Open accessRead summary

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