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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

AllClinical ResearchCase Reports
FeaturedCase ReportNeurology

PHACE syndrome: a systematic literature review and illustrative case report of a patient with severe cerebrovascular and neurodevelopmental sequelae.

Neurol SciSep 4, 2026Open access

A 12-year-old girl with PHACE syndrome presented with a left V1-distribution facial hemangioma and significant cerebrovascular complications, including neonatal intraventricular hemorrhage, hydrocephalus, and a dural…

Clinical pearl

Clinicians should be aware that cerebrovascular complications in PHACE syndrome can develop years after initial diagnosis, necessitating ongoing surveillance.

Read case

Also worth knowing

Case ReportPediatrics

Malignant pertussis in a young infant.

A young infant presented with malignant pertussis, characterized by extreme leucocytosis and respiratory failure, alongside additional bloodstream infections during hospitalization.

BMJ Case RepSep 8, 2026Read case
Case ReportNephrology

Levamisole-induced anti-neutrophil cytoplasmic antibodies-associated vasculitis in paediatric nephrotic syndrome: dose-dependent and idiosyncratic risks in paediatric patients.

Two pediatric cases of levamisole-induced vasculitis are reported, highlighting the risks associated with this medication in managing nephrotic syndrome.

BMJ Case RepSep 5, 2026Read case
Case ReportHematology

Blinatumomab-induced catastrophic immune effector cell-associated neurotoxicity with diffuse cerebral edema in a patient with ALL: Case report.

A 13-year-old boy with MLL-AF4-positive precursor B-ALL developed catastrophic neurotoxicity during blinatumomab therapy. After initially tolerating treatment, he experienced fever on day 13 of the second cycle, leading…

Int J Clin Pharmacol TherSep 9, 2026Read case
Case ReportOncology (Medical)

Recurrent C19MC-altered embryonal tumors with multilayered rosettes: outcomes of stereotactic radiosurgery.

This report discusses three pediatric patients with recurrent embryonal tumors with multilayered rosettes (ETMR) who were treated with stereotactic radiosurgery (SRS) after initial gross total resection and adjuvant…

Childs Nerv SystSep 9, 2026Open accessRead case
Case ReportCardiology

Successful bridge to heart transplantation in a pediatric patient with biventricular heart failure associated with Barth syndrome: a case report.

A one-year-old boy with Barth syndrome presented in cardiogenic shock due to severe biventricular heart failure. He received emergency biventricular assist device support, with innovative management of the right…

J Artif OrgansSep 8, 2026Open accessRead case
Case ReportCardiothoracic Surgery

Tricuspidization of a unicuspid aortic valve in an adolescent using selective single-cusp replacement.

An adolescent with a unicuspid aortic valve exhibiting stenosis and regurgitation underwent a novel tricuspidization procedure.

Multimed Man Cardiothorac SurgSep 8, 2026Read case
Case ReportHematology

Successful Engraftment Following Second Cord Blood Transplantation After Graft Failure in a Child With Relapsed B-ALL.

A 9-year-old boy with relapsed B-cell precursor acute lymphoblastic leukemia experienced primary graft failure after his first umbilical cord blood transplantation due to low CD34-positive cell dose and significant HLA…

Tokai J Exp Clin MedSep 6, 2026Read case
Case ReportNephrology

Subcutaneous Alemtuzumab as Salvage Therapy for Acute Kidney Transplant Rejection Following Thymoglobulin Anaphylaxis: A Pediatric Case Report.

A 12-year-old male with end-stage kidney disease due to congenital renal dysplasia underwent kidney transplantation and presented 9 years later with acute allograft dysfunction.

Pediatr TransplantSep 1, 2026Open accessRead case
Case ReportGastroenterology

Novel SLC10A2 variants induce primary bile acid malabsorption and dysbiosis with IBD-like features.

We describe biochemically and functionally validated primary bile acid malabsorption caused by novel biallelic SLC10A2 variants in a child initially diagnosed with Crohn's disease.

Inflamm Bowel DisSep 1, 2026Open accessRead case
Case ReportPediatrics

"It Wasn't Nonadherence": Administrative Workload for Families and Inequitable Outcomes.

Mateo, a 7-year-old with medical complexity, was admitted for respiratory distress. His hospitalization was complicated by systemic issues, including language barriers and administrative demands that hindered his…

Hosp PediatrSep 1, 2026Read case
Case ReportPediatrics

Anakinra in Severe RSV-Associated Autoinflammatory Encephalopathy With Delayed ADEM-Like Changes.

Two previously healthy children developed rapidly progressive encephalopathy following RSV infection. Initial brain MRI scans were normal, but subsequent imaging revealed multifocal white matter lesions resembling acute…

PediatricsSep 1, 2026Read case

Showing 12 of 31 publications that cleared our clinical screen in the last 14 days.

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