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653 articles
October 202624
Effectiveness of Exercise Snacks in Mitigating Adolescent Problematic Smartphone Use: A Four-Wave Cluster Randomized Controlled Trial.
This four-wave cluster randomized controlled trial tested whether brief, vigorous activity breaks could reduce problematic smartphone use among 386 adolescents in 12 secondary-school classes.
Immediate vs delayed extubation after pediatric liver transplantation: a systematic review and meta-analysis.
This systematic review and meta-analysis compared immediate operating-room extubation with delayed extubation after pediatric orthotopic liver transplantation.
Balancing safety and efficacy in photodynamic therapy for facial port-wine stains in children aged 2-7 years: a prospective controlled study of light-intensity optimization.
This open-label, prospective controlled study compared two light intensities for hemoporfin-mediated photodynamic therapy in children aged 2–7 years with facial port-wine stains.
Clinical and radiographic success of bioflex versus stainless steel crowns using the hall technique in primary molars: a 12-month randomized controlled trial.
This two-arm randomized controlled trial compared BioFlex crowns (BFCs) with stainless-steel crowns (SSCs), both placed using the Hall Technique, in healthy children aged 4–6 years with carious mandibular second primary…
Silver diamine fluoride versus conventional restorative treatment for dental caries in primary teeth of children: a meta-analysis.
This meta-analysis compared 30% to 38% silver diamine fluoride (SDF) with conventional restorative approaches for caries control in children with carious primary teeth.
Clinical performance of resin infiltration and different sealant modalities in noncavitated pits and fissures: a split-mouth randomized controlled trial.
This split-mouth randomized controlled trial compared resin infiltration, two sealant approaches, and their combination for noncavitated occlusal lesions in 128 permanent molars from 32 children aged 7–14 years.
Sevuparin in children with severe malaria: a phase I safety and dose-finding trial.
This phase I dose-finding trial assessed sevuparin safety and tolerability in Kenyan and Zambian children with severe malaria.
Parent-child discrepancies in health-related quality of life in pediatric celiac disease: a systematic review and meta-analysis.
This systematic review and meta-analysis examined child–parent differences in health-related quality of life (HRQoL) among children and adolescents with celiac disease, using the disease-specific CDDUX questionnaire.
Ruxolitinib for the treatment of pediatric acute and chronic steroid-refractory graft-versus-host disease: Efficacy, safety, and outcomes.
This single-center retrospective study assessed ruxolitinib in children under 18 years with steroid-refractory graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.
Levetiracetam versus valproate for new-onset or previously treated but inadequately controlled epilepsy in children: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis compared levetiracetam with valproate in children aged 0–18 years with new-onset or inadequately controlled epilepsy.
Effectiveness and Influencing Factors of Drama-Based Interventions for Social Skills in Children and Adolescents with Autism Spectrum Disorder: A Meta-Analysis.
This meta-analysis assessed drama-based interventions for social skills in children and adolescents with autism spectrum disorder (ASD), drawing on 16 controlled studies involving 703 participants.
Neurosurgical manifestations and management of mucopolysaccharidoses: A systematic review.
This PRISMA-guided systematic review synthesized contemporary reports of neurosurgical manifestations and management across mucopolysaccharidosis (MPS) subtypes.
Neonatal gastric perforation: a systematic review and meta-analysis of clinical characteristics, risk factors, surgical management and outcomes.
This systematic review and meta-analysis examined clinical features, risk factors, surgical management and outcomes of neonatal gastric perforation using observational studies of neonates aged 28 days or younger.
Ciliated hepatic foregut cyst in children and adolescents: a systematic review of clinical presentation, diagnosis, management, and outcomes.
This PRISMA 2020 systematic review descriptively synthesised case reports and case series of histopathologically confirmed ciliated hepatic foregut cysts in patients aged 19 years or younger.
The effect of seizure-free period on seizure recurrence following antiseizure medication withdrawal: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis examined whether the duration of seizure freedom before antiseizure medication (ASM) withdrawal is associated with subsequent seizure recurrence in people with…
Oxygen vs Air at Birth for Moderate- to Late-Preterm Infants: The AIROPLANE Cluster Randomized Crossover Trial.
The AIROPLANE trial was an unblinded, cluster randomized crossover study at 26 Australian maternity hospitals comparing initial oxygen concentrations of 0.30 and 0.21 during the first 3 minutes of respiratory support…
The impact of recreational beach tennis associated with nutritional counseling on cardiometabolic risk factors in adolescents: a randomized clinical trial.
This 12-week randomized clinical trial compared recreational beach tennis alone with beach tennis plus nutritional counseling in 40 adolescents aged 11–14 years.
Paediatric Helicobacter pylori infection and allergic and inflammatory diseases: a contemporary systematic review with meta-analysis.
This systematic review and meta-analysis assessed recent evidence on Helicobacter pylori infection and allergic or immune-mediated diseases in children.
Clinical and functional outcomes of aquatic plyometrics in adolescent patellofemoral pain syndrome: a dual-arm randomized controlled trial.
This dual-arm randomized controlled trial compared aquatic plyometric exercises with conventional exercises in 56 adolescents aged 10–18 years with patellofemoral pain syndrome.
Comparable efficacy of extraoral and intraoral photobiomodulation in preventing oral mucositis during high-dose methotrexate therapy in pediatric oncology: A single-blind randomized controlled trial.
This single-blind randomized controlled trial compared intraoral (IO) with extraoral (EO) photobiomodulation (PBM) to prevent oral mucositis in 155 children and adolescents receiving high-dose methotrexate for leukemia…
Effectiveness of digital educational technologies in knowledge acquisition for adolescent health promotion: a systematic review.
This systematic review assessed whether digital educational technologies improve health-promotion knowledge among adolescents.
Switching from Intravenous to Subcutaneous Infliximab in Children with Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis synthesized six independent, largely observational cohorts of children with inflammatory bowel disease who switched from intravenous to subcutaneous infliximab (n = 173).
Pulpotomy of deciduous molars with deep caries using three different hydraulic calcium silicate cements: a short-term pilot randomized controlled split-mouth study.
This short-term pilot randomized controlled split-mouth study compared three hydraulic calcium silicate cements for pulpotomy in carious primary molars of children aged 2–6 years treated under general anesthesia.
The Impact of Ambient Ozone Exposure on Respiratory Health in the U.S. Populations: A Systematic Review.
This systematic review synthesized U.S. epidemiologic and experimental studies published from 1980 to 2026 on acute and chronic ambient ozone exposure and respiratory health.
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