Septic arthritis due to Corynebacterium striatum in native joints: a systematic review of published cases.
Sara Rivera Posada, Pablo Camacho Zamora, Lucía Pasarín López et al.
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In 30 seconds
This systematic review analyzed 12 published cases of septic arthritis caused by Corynebacterium striatum in native joints. Most patients presented with acute monoarticular arthritis, primarily affecting large joints like the knee and shoulder. Predisposing factors were noted in nearly all cases, and management typically involved surgical intervention and prolonged antimicrobial therapy, with favorable overall outcomes despite some severe complications.
Key findings
- Twelve cases of septic arthritis due to C. striatum were identified, primarily affecting large joints.
- Predisposing factors included advanced age, immunosuppression, and recent joint manipulation in nearly all cases.
- Synovial fluid analysis showed a marked inflammatory profile, supporting the diagnosis.
- Management often involved surgical irrigation and prolonged antimicrobial therapy, most commonly vancomycin.
Why it matters
Recognizing Corynebacterium striatum as a potential cause of septic arthritis is crucial for timely diagnosis and appropriate treatment, especially in high-risk patients. Misclassification as a contaminant can lead to delayed care and poor outcomes.