A Rare Case of Four-year Complete Metabolic Response in Multisystem Anti-Jo-1 Antisynthetase Syndrome Assessed by 18 F-FDG PET/CT.

Clin Nucl MedMay 19, 2026 (epub)
Case ReportRheumatologyPulmonologyRadiology (Diagnostic)

Julien Dubois, Olivier Delcroix, Christelle Gallego et al.

✦ AI-curated · Sources linked

Case in brief

A patient with anti-Jo-1 positive antisynthetase syndrome presented with muscular, articular, cutaneous, and pulmonary involvement. The condition was assessed using 18 F-FDG PET/CT, which revealed significant abnormalities. Remarkably, after four years of follow-up, the patient achieved a complete metabolic response with resolution of all abnormalities, and no malignancy was detected.

Diagnostic / clinical pearl

The use of 18 F-FDG PET/CT can be valuable in both the initial assessment and ongoing monitoring of antisynthetase syndrome, aiding in the detection of disease activity and exclusion of malignancy.

Source

PubMed · PMID 42257453

Published in Clin Nucl Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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