Disseminated Mucormycosis and monoclonal gammopathy in a young sarcoidosis patient following COVID-19: A rare case report.
Hossam A Abady, Mohamed M El-Khatib, Nadine Soliman et al.
✦ AI-curated · Sources linked
Case in brief
A previously healthy 25-year-old male developed disseminated mucormycosis following COVID-19, alongside sarcoidosis and IgG-kappa monoclonal gammopathy. He presented with progressive respiratory symptoms and multi-organ involvement, confirmed by histopathology and PCR. Despite treatment with amphotericin B, he succumbed to septic shock and multiorgan failure, highlighting the severity of this fungal infection in immunocompromised patients.
What made this case unusual
The case is notable for the development of disseminated mucormycosis in a young, previously healthy individual with newly diagnosed sarcoidosis and monoclonal gammopathy following COVID-19, illustrating a rare association.
Diagnostic / clinical pearl
Clinicians should maintain a high index of suspicion for opportunistic infections like mucormycosis in patients with recent COVID-19 and underlying immunocompromising conditions.
Why it matters
This case emphasizes the need for early detection and aggressive treatment of invasive fungal infections in patients with concurrent granulomatous diseases and hematological abnormalities.