Systematic review of prognostic scores and individual predictor variables for short-term mortality after acute pulmonary embolism.
David Jimenez, Behnood Bikdeli, Victor Tapson et al.
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In 30 seconds
This systematic review evaluated prognostic models and individual predictors for short-term mortality in patients with acute pulmonary embolism (PE), analyzing 314 studies involving 2,495,115 patients. The review identified 24 prognostic models, with the simplified Pulmonary Embolism Severity Index (sPESI) being the most frequently used. Key individual predictors included older age and right heart thrombi, with pooled odds ratios for predictors ranging from 1.43 to 2.65.
Key findings
- Identified 24 prognostic models for short-term mortality after acute PE.
- The simplified Pulmonary Embolism Severity Index (sPESI) was used in 127 studies.
- Pooled odds ratio for right heart thrombi was 2.65.
- Older age and coexisting conditions were significant individual predictors.
Why it matters
Understanding prognostic factors in acute pulmonary embolism is crucial for risk stratification and management decisions, enabling healthcare providers to tailor care based on individual patient risk profiles.