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1998 articles
October 202624
Efficacy and safety of subcutaneous efgartigimod with prednisone in moderate-to-severe pemphigus (ADDRESS): a global, phase III, randomised controlled, double-blind trial.
ADDRESS was a global, phase III, multicentre, randomised, double-blind, placebo-controlled trial of adults with newly diagnosed or relapsing moderate-to-severe pemphigus.
Outdoor cycling competence and balance control in older adults - cross-sectional analysis of the BiPerAge trial.
This exploratory cross-sectional analysis used baseline data from a two-center randomized controlled trial to examine balance and outdoor cycling competence in 116 community-dwelling adults aged ≥ 65 years who made at…
Clinical and functional outcomes of aquatic plyometrics in adolescent patellofemoral pain syndrome: a dual-arm randomized controlled trial.
This dual-arm randomized controlled trial compared aquatic plyometric exercises with conventional exercises in 56 adolescents aged 10–18 years with patellofemoral pain syndrome.
Contrast-Enhanced Ultrasound Combined With Biopsy for the Preoperative Diagnosis of a Rare Pelvic Schwannoma: A Case Report.
A 66-year-old man with dysuria and lumbago had a large mixed cystic-solid pelvic mass. Conventional ultrasound showed limited Doppler flow; contrast-enhanced ultrasound (CEUS) demonstrated progressive…
Tranexamic acid in laparoscopic sleeve gastrectomy: bleeding control amid thrombotic concerns and hemodynamic instability: a randomized double-blinded clinical trial.
This randomized, double-blinded clinical trial assessed tranexamic acid (TXA) for perioperative bleeding prevention in 185 patients with morbid obesity undergoing elective laparoscopic sleeve gastrectomy.
Characterizing Behavioral Engagement in Smartphone Cognitive Behavioral Therapy for Obsessive Compulsive Disorder: Secondary Analysis of a Randomized Controlled Trial.
This exploratory secondary analysis of a 12-week randomized controlled trial examined behavioral engagement with smartphone cognitive behavioral therapy for obsessive compulsive disorder (OCD) in 60 participants.
Daily consumption of unsalted, skin-roasted peanuts beneficially affects regional brain insulin responsiveness in older adults: results of a longer-term randomized controlled trial.
This randomized, single-blind, controlled crossover trial examined whether peanut intake altered brain insulin responsiveness in 31 older adults (67 ± 4 years).
Effectiveness of physical, psychological, and alternative interventions for post-COVID-19 condition: a systematic review.
This systematic review of randomized controlled trials assessed supervised, face-to-face non-pharmacological interventions in adults with WHO-defined post-COVID-19 condition.
Metal Hypersensitivity Reactions Following Spinal Implants: A Systematic Review.
This systematic review examined clinical presentation, diagnostic approaches, and outcomes of metal hypersensitivity after spinal implant surgery in adults.
Safety and effectiveness of the Vertex Pulmonary Embolectomy System in acute intermediate-risk pulmonary embolism: the SPIRARE II pivotal trial.
SPIRARE II was a prospective, single-arm, multicentre pivotal trial evaluating the Vertex Pulmonary Embolectomy System for aspiration thrombectomy in patients with acute intermediate-risk pulmonary embolism.
Comparable efficacy of extraoral and intraoral photobiomodulation in preventing oral mucositis during high-dose methotrexate therapy in pediatric oncology: A single-blind randomized controlled trial.
This single-blind randomized controlled trial compared intraoral (IO) with extraoral (EO) photobiomodulation (PBM) to prevent oral mucositis in 155 children and adolescents receiving high-dose methotrexate for leukemia…
Isolated Bilateral Periocular Lupus Miliaris Disseminatus Faciei: A Clinicopathological Mimicker of Granulomatosis With Polyangiitis.
A healthy young adult man presented with symmetrical papules confined to both periocular regions. Eyelid biopsy showed suppurative necrotizing granulomatous inflammation, prompting concern for granulomatosis with…
Clinical Recovery Following Conservative Management of a Large Presumed Brain Abscess with a Concomitant Streptococcus intermedius Lung Abscess in a Severely Malnourished Young Adult in a Resource-Limited Setting: A Case Report.
A severely malnourished 22-year-old man presented with progressive left-sided weakness after weeks of productive cough, fever, and weight loss. Examination showed impaired consciousness and flaccid hemiplegia.
Psychological Factors Associated with Function and Health-Related Quality of Life Outcomes following Total Hip or Knee Arthroplasty: An Umbrella Review of Systematic Reviews.
This umbrella review synthesised high-quality evidence from systematic reviews on psychological factors associated with function and health-related quality of life after total hip or knee arthroplasty.
Effects of the GnRH agonist leuprorelin on liver volume in premenopausal women with severe polycystic liver disease.
This prospective, open-label randomized trial evaluated leuprorelin in premenopausal women aged 18–45 years with severe polycystic liver disease (PLD).
Comparison of outcomes after direct extracranial-to-intracranial bypass for moyamoya disease and non-moyamoya pathology: A systematic review and meta-analysis.
This systematic review and meta-analysis compared direct extracranial-to-intracranial (EC-IC) bypass outcomes in adults with moyamoya disease or syndrome (MMD) versus non-moyamoya steno-occlusive disease, mainly…
Walnut consumption improves mood and is associated with increased urinary excretion of 5-hydroxyindoleacetic acid and urolithins in a randomized crossover trial.
This 18-week open-label randomized crossover trial assessed whether daily walnut consumption affected mood and urinary metabolites in 31 healthy young adults.
Conventional Skull Base Chordoma in a Ugandan Adult Male, Presenting with Prolonged Headache: A Case Report.
A 49-year-old man had more than a year of intermittent, progressively worsening headache and reported an episode of facial numbness, although facial sensation and the remainder of his neurological examination were…
Association of dietary choline intake with cognitive decline and related outcomes: a systematic review and dose-response meta-analysis of observational studies.
This systematic review and dose-response meta-analysis examined observational evidence on dietary choline intake and cognitive decline or related outcomes.
Delayed diagnosis of cerebrotendinous xanthomatosis with progressive neurological involvement: a case report.
A 34-year-old man with genetically confirmed cerebrotendinous xanthomatosis presented with progressive gait instability, dysarthria, dysphagia, and cognitive impairment.
Coronary artery disease management in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation: a systematic review and meta-analysis of randomised controlled trials.
This systematic review and meta-analysis of randomised trials compared coronary revascularisation strategies in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI).
Technological Integration in Triage With AI and Machine Learning Compared With Conventional Triage and Narrative Synthesis of Telehealth for Patient Prioritization in Emergency and Acute Care Settings: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed AI- and machine-learning-assisted triage alongside tele-triage and digital tools in emergency and acute care.
Paediatric Helicobacter pylori infection and allergic and inflammatory diseases: a contemporary systematic review with meta-analysis.
This systematic review and meta-analysis assessed recent evidence on Helicobacter pylori infection and allergic or immune-mediated diseases in children.
High-Resolution Ultrasound in the Evaluation of Median and Superficial Radial Nerve Involvement in Neurofibromatosis Type 1.
A 16-year-old girl with neurofibromatosis type 1 presented with hand pain and paresthesia. High-resolution ultrasound showed a hypervascular superficial neurofibroma, marked epineural thickening of the median nerve…
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