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1998 articles

October 202624

Clinical ResearchGeriatrics

Effectiveness of traditional mind-body exercises on fall risk test scores and balance in older adults: A systematic review and meta-analysis.

This systematic review and meta-analysis pooled 31 randomized controlled trials involving 3,622 older adults to assess traditional mind-body exercises and fall-risk test scores and balance.

Medicine (Baltimore)Oct 16, 2026Read summary
Case ReportHematology

Iptacopan combined with immunosuppressive therapy for aplastic anemia-paroxysmal nocturnal hemoglobinuria syndrome: A case report.

A previously healthy 24-year-old man presented with dizziness, fatigue, and pancytopenia. Bone marrow examination supported aplastic anemia, with a PNH clone also identified.

Medicine (Baltimore)Oct 16, 2026Read case
Clinical ResearchNephrology

Local ancestry-aware genome-wide meta-analysis uncovers novel genetic loci for sickle cell disease nephropathy.

This local ancestry-aware genome-wide association meta-analysis examined estimated glomerular filtration rate in participants from two well-characterized adult sickle cell disease cohorts, seeking genetic loci…

Blood AdvOct 16, 2026Read summary
Clinical ResearchMedical Genetics

The extra X chromosome and autoimmune susceptibility in Klinefelter syndrome.

This systematic review and meta-analysis assessed autoimmune susceptibility in people with Klinefelter syndrome (47,XXY), using studies of autoimmune disease and serological markers.

J Clin Endocrinol MetabOct 16, 2026Read summary
Case ReportCardiology

Dysregulation of glycogen metabolism in cardiomyopathy caused by glycogenin-1 (GYG1) missense variants.

The report describes a new case of glycogen storage disease type 15 (GSD15), alongside analysis of heart explants from two previously reported patients.

J Clin Endocrinol MetabOct 16, 2026Read case
Case ReportPulmonology

Life-threatening diffuse alveolar hemorrhage associated with Rhinovirus infection and the potential role of corticosteroids in immunocompetent patients: Case reports.

Two immunocompetent women, aged 85 and 70, presented with severe hypoxemia and hemoptysis or worsening dyspnea. Chest CT showed diffuse or bilateral ground-glass opacities and consolidations.

Medicine (Baltimore)Oct 16, 2026Read case
Clinical ResearchCardiology

Dapagliflozin After Transcatheter Aortic Valve Implantation According to Frailty in DapaTAVI Trial.

This post hoc analysis of the multicenter randomized DapaTAVI trial examined whether frailty modified dapagliflozin’s effects after transcatheter aortic valve implantation.

J Am Heart AssocOct 16, 2026Read summary
Case ReportCardiothoracic Surgery

Large Carinal Chondrosarcoma: Resection of the Main Carina, Distal Trachea, and Orifices of the Mainstem Bronchi and Construction of a New Carina.

A 23-year-old man presented with dyspnea, fatigue, and cough. CT showed a lobulated mass anterior to the distal trachea and main carina; bronchoscopy demonstrated carinal widening, significant stenosis of both mainstem…

Am J Case RepOct 16, 2026Read case
Clinical ResearchPathology (Anatomic & Clinical)Open access

SOX10 Expression in Primary Salivary Gland Tumors: A Meta-Analysis.

This PRISMA-guided systematic review and meta-analysis assessed SOX10 immunohistochemical expression across primary salivary gland tumors. It included 35 studies comprising 1146 histological and 35 cytological samples.

Head Neck PatholOct 16, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Effectiveness of different autologous platelet concentrates for orthodontic canine retraction following premolar extraction: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed platelet-rich plasma (PRP), injectable platelet-rich fibrin (i-PRF), and leukocyte-platelet-rich fibrin (L-PRF) for accelerating orthodontic canine retraction after…

Prog OrthodOct 16, 2026Read summary
Clinical ResearchNephrology

Peritoneal catheter fixation versus nonfixation in open surgery: A meta-analysis.

This meta-analysis compared fixation with nonfixation of peritoneal dialysis (PD) catheters placed by open surgery. Thirteen studies included 648 patients in the fixation group and 627 in the nonfixation group.

Medicine (Baltimore)Oct 16, 2026Read summary
Case ReportOrthopedic Surgery

Third lumbar transverse process syndrome with acute abdominal pain as the main clinical manifestation: A case report.

A 66-year-old man presented with persistent left lower-quadrant abdominal pain radiating to the lower back, worsened by postural change, standing, and walking.

Medicine (Baltimore)Oct 16, 2026Read case
Case ReportNeurology

Spontaneous gene mutation encounters a paternal genetic variant: Nemaline myopathy: a case report and literature review.

A 21-year-old man had progressive weakness beginning in the distal lower limbs at age 3, later affecting proximal and masticatory muscles.

Medicine (Baltimore)Oct 16, 2026Read case
Clinical ResearchEmergency Medicine

Neutrophil to lymphocyte ratio for predicting delayed neurologic sequelae caused by carbon monoxide poisoning: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed whether the neutrophil-to-lymphocyte ratio (NLR) predicts delayed neurologic sequelae (DNS) after acute carbon monoxide poisoning.

Medicine (Baltimore)Oct 16, 2026Read summary
Case ReportPediatrics

A case of neonatal gastric perforation misdiagnosed as neonatal necrotizing enterocolitis: A literature review.

A male infant born at 33 weeks and 5 days presented on day four of life with abdominal distension, feeding refusal, and no passage of flatus or stool.

Medicine (Baltimore)Oct 16, 2026Read case
Case ReportOtolaryngology (ENT)

Ectopic thyroid tissue accompanied by distinct blood supply and lymphoid tissue within the carotid sheath - a case report.

A 42-year-old man had an asymptomatic right-sided neck mass detected during a routine examination. Ultrasound showed a normally located thyroid and a well-defined 1.3 cm × 0.9 cm × 0.5 cm mass with echotexture similar…

Medicine (Baltimore)Oct 16, 2026Read case
Case ReportNephrology

Complete remission of minimal change disease after antiviral monotherapy in a patient with immune-active chronic hepatitis B: A case report.

A 42-year-old woman presented with generalized edema, weight gain, hypoalbuminemia, and nephrotic-range proteinuria, with a urine protein-to-creatinine ratio of 4.3 and preserved renal function.

Medicine (Baltimore)Oct 16, 2026Read case
Clinical ResearchEndocrinology

Bone phenotype of patients with genetic forms of lipodystrophy: a systematic review of literature.

This systematic review examined bone manifestations in people with genetic lipodystrophies, using human studies identified through searches of PubMed, EMBASE, and the Cochrane Library.

J Clin Endocrinol MetabOct 16, 2026Read summary
Case ReportCardiothoracic SurgeryOpen access

Optimization of Anticoagulation Strategy During Cardiopulmonary Bypass in Neonates with Congenital Heart Disease: A Randomized Controlled Trial.

Neonatal hemostatic immaturity complicates anticoagulation during cardiopulmonary bypass (CPB). Current practice largely follows the strategy of 400 U/kg from adult protocols, as neonatal-specific guidelines and…

Drug Des Devel TherOct 15, 2026Read case
Clinical ResearchOncology (Medical)

Long-term Results of Multiantigen Stimulated Cell Therapy I, Alone or in Combination with Chemotherapy, as First-line Maintenance Therapy in Advanced Sarcoma: A Multicenter, Phase I Trial.

This multicenter, phase I trial evaluated multiantigen stimulated cell therapy I (MASCT-I), alone or with ifosfamide, as first-line maintenance therapy in 31 patients with advanced sarcoma whose disease was controlled…

Clin Cancer ResOct 15, 2026Read summary
Clinical ResearchOncology (Medical)

Feasibility and Activity of Concurrent Neoadjuvant Chemotherapy and Radiotherapy in Patients with High-risk Soft-Tissue Sarcoma.

This analysis of the international, randomized phase III ISG-STS 1001 trial assessed concurrent epirubicin–ifosfamide chemotherapy (EI) and radiotherapy in patients with localized, high-risk soft-tissue sarcoma.

Clin Cancer ResOct 15, 2026Read summary
Clinical ResearchMedical Genetics

Safety and efficacy of delpacibart zotadirsen in Duchenne muscular dystrophy mutations amenable to exon 44 skipping in the USA (EXPLORE44): a randomised, placebo-controlled, double-blind, phase 1/2 trial.

EXPLORE44 was a two-part, randomised, double-blind, placebo-controlled phase 1/2 trial at ten US sites, studying delpacibart zotadirsen (del-zota) in healthy adult men and in ambulatory and non-ambulatory males aged…

Lancet NeurolOct 15, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Uniportal versus Multiportal Video-Assisted Thoracoscopic Surgery for Minimally Invasive Esophagectomy in Esophageal Cancer: A GRADE-Assessed Systematic Review and Meta-Analysis.

This GRADE-assessed systematic review and meta-analysis compared uniportal (uVATS) with multiportal video-assisted thoracoscopic surgery (mVATS) for minimally invasive esophagectomy in adults with esophageal cancer.

J Gastrointest CancerOct 15, 2026Read summary
Clinical ResearchOncology (Medical)

Multicenter Phase I Study of Triapine in Combination with [177Lu]Lutetium-Dotatate in Patients with Well-Differentiated Neuroendocrine Tumors (ETCTN 10388).

This multicenter phase I dose-escalation and dose-expansion study evaluated [177Lu]lutetium-dotatate plus oral triapine in patients with well-differentiated gastroenteropancreatic neuroendocrine tumors.

Clin Cancer ResOct 15, 2026Read summary

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