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1998 articles

October 202624

Case ReportPediatrics

68Ga-DOTATATE PET/CT Detection of Hypertrophic Osteoarthropathy in a Pediatric Patient With Neuroblastoma Following Anti-GD2 Immunotherapy.

A 5-year-old boy with high-risk neuroblastoma underwent 68Ga-DOTATATE PET/CT to assess response after anti-GD2 immunotherapy.

Clin Nucl MedOct 8, 2026Read case
Clinical ResearchHematology

Anticoagulation with the mechanistically distinct FXI/FXIa antibodies amrecibart (REGN9933A2) and cenvacibart (REGN7508Cat).

This Phase I randomised controlled trial programme evaluated two mechanistically distinct factor XI/FXIa monoclonal antibodies as potential anticoagulants, using in vitro assays, nonhuman primates and healthy…

BloodOct 8, 2026Read summary
Case ReportInfectious DiseasesOpen access

Varicella zoster virus meningitis with a dermatomal rash in immunocompetent hosts: a systematic review and novel case report.

A 44-year-old immunocompetent man presented with fever, severe headache, and a right-sided vesicular rash in the C4-C5 dermatomes. He was initially misdiagnosed with a tick-borne illness.

J NeurovirolOct 8, 2026Read case
Case ReportOphthalmologyOpen access

Trigeminal sensory neuropathy developing as a late complication after the treatment of surgically induced necrotizing scleritis following pterygium surgery: a case report and literature review.

A 31-year-old woman developed right-eye irritation, reduced vision, and photophobia after bilateral pterygium surgery. Examination showed melting of the conjunctival autograft with exposed sclera and a visible choroidal…

BMC OphthalmolOct 8, 2026Read case
Clinical ResearchEndocrinology

Changes in ectopic lipids, insulin sensitivity, and beta cell function after a low-fat vegan diet in adults with type 2 diabetes: a 16-week single-arm clinical trial.

This 16-week, single-arm clinical trial examined changes in ectopic lipids, insulin sensitivity, advanced glycation end products, and beta-cell function in 25 adults with type 2 diabetes following an ad libitum low-fat…

BMJ Open Diabetes Res CareOct 8, 2026Read summary
Clinical ResearchNeurology

Effects of Blood Pressure Lowering by Hematoma Location in Acute Intracerebral Hemorrhage.

This pooled individual-patient analysis of five international randomised controlled trials examined whether hematoma location modifies the effect of early intensive blood pressure lowering in acute intracerebral…

NeurologyOct 8, 2026Read summary
Clinical ResearchNeurologyOpen access

Clinical and Electrophysiological Heterogeneity of Orthostatic Tremor: An Individual Patient Data Analysis.

Orthostatic tremor (OT) is traditionally classified using tremor frequency and the presence of associated neurological signs.

Tremor Other Hyperkinet Mov (N Y)Oct 8, 2026Read summary
Clinical ResearchPsychiatryOpen access

The relationship between fear of negative evaluation and social anxiety: a systematic review and meta-analysis.

This systematic review and meta-analysis examined the association between fear of negative evaluation (FNE) and social anxiety (SA) across 143 studies and 146 independent samples, including 80,285 participants.

BMC PsycholOct 8, 2026Read summary
Case ReportAnesthesiologyOpen access

Ilioinguinal-Transversus Abdominis Plane (I-TAP) Block with Liposomal Bupivacaine for Analgesia After Cesarean Delivery: A Randomized Controlled Trial.

Cesarean delivery is frequently associated with suboptimal postoperative analgesia. While PROSPECT guidelines recommend transversus abdominis plane (TAP) block for post-cesarean analgesia, conventional TAP block may…

Drug Des Devel TherOct 8, 2026Read case
Case ReportGeneral Surgery

Perioperative Nursing Care of a Patient With 70% TBSA Second- To Third-Degree Flame Burns Complicated by Pseudomonas aeruginosa Infection: A Case Report.

A patient with 70% TBSA second- to third-degree flame burns developed a Pseudomonas aeruginosa infection and required surgical care, including back debridement.

Nurs Crit CareOct 8, 2026Read case
Clinical ResearchNeurology

Intracerebral stimulation inducing emotions in SEEG: a systematic review.

This systematic review examined subjective emotional responses to direct intracerebral stimulation during SEEG, synthesizing 34 publications (21 cohort studies and 13 clinical cases) involving 2434 patients and 14,492…

NeuroimageOct 8, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Effect of Anterior Quadratus Lumborum Block at the Lateral Supra-Arcuate Ligament Combined with Esketamine on the Quality of Postoperative Recovery After Laparoscopic Radical Surgery for Elderly Patients with Colorectal Cancer: A Randomized Controlled Trial.

This single-centre, randomized, placebo-controlled trial evaluated anterior quadratus lumborum block at the lateral supra-arcuate ligament (QLB-LSAL), low-dose esketamine, or their combination in patients aged 60 years…

Drug Des Devel TherOct 8, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Comparison of two repetitive peripheral magnetic stimulation protocols for upper trapezius myofascial pain syndrome: A randomized trial.

This single-centre, assessor-blinded randomized trial compared 10- and 15-minute repetitive peripheral magnetic stimulation (rPMS) protocols, each given weekly for 4 weeks alongside stretching, in adults aged 18–55 with…

PLoS OneOct 8, 2026Read summary
Clinical ResearchInfectious Diseases

Association between complement de-escalation and prognosis in sepsis: A systematic review and meta-analysis.

This systematic review and meta-analysis examined whether reduced complement activation after treatment was associated with prognosis in patients with sepsis. Eleven studies were included.

Respir MedOct 8, 2026Read summary
Clinical ResearchPsychiatry

Estimating the Economic Value of Supported Online Parent-Led Cognitive Behavioral Therapy to Prevent Child Anxiety Problems: Economic Evaluation of the MYCATS Cluster Randomized Controlled Trial.

This economic evaluation alongside the MYCATS parallel-group, superiority cluster randomised trial assessed supported online parent-led cognitive behavioural therapy (OSI+TS) plus usual school practice versus usual…

J Med Internet ResOct 8, 2026Read summary
Case ReportMedical GeneticsOpen access

Case Report: Atypical femoral fractures in adult-onset hypophosphatasia treated with low-dose asfotase alfa and adjunctive teriparatide therapy.

A 52-year-old woman presented with progressive pain and bilateral atypical femoral fractures. Low alkaline phosphatase, markedly elevated pyridoxal 5'-phosphate, prior metatarsal fracture, premature tooth loss, and…

Front Endocrinol (Lausanne)Oct 8, 2026Read case
Clinical ResearchPulmonologyOpen access

Comparative effects of inspiratory and expiratory muscle training on diaphragm adaptations and respiratory function in adolescent athletes: a randomized-controlled study.

This randomized controlled study compared inspiratory muscle training (IMT) with expiratory muscle training (EMST) in 26 adolescent female volleyball players.

BMC PediatrOct 8, 2026Read summary
Clinical ResearchGeriatrics

Adverse childhood experiences, cognitive outcomes, and frailty in older adults: a systematic review and meta-analysis.

This systematic review and meta-analysis examined associations between adverse childhood experiences (ACEs) and frailty or cognitive outcomes in middle-aged and older adults.

GerontologistOct 8, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Effect of amaranth flatbread on maternal anthropometry during pregnancy: Evidence from a cluster-randomized controlled trial in Southern Ethiopia.

This parallel-group, cluster-randomized controlled trial assessed daily amaranth-chickpea flatbread in pregnant women with mild-to-moderate anemia in Southern Ethiopia.

PLoS OneOct 8, 2026Read summary
Case ReportNeurologyOpen access

Bobble-Head Doll Syndrome Caused by Aqueductal Web-Associated Obstructive Hydrocephalus in an Adult: A Case Report with Video.

A 24-year-old man developed progressive memory impairment, gait instability, urinary incontinence, and an irregular side-to-side (“no-no”) head tremor that improved with a sensory trick.

Tremor Other Hyperkinet Mov (N Y)Oct 8, 2026Read case
Clinical ResearchOphthalmology

Optogenetic Therapy for Restoring Aspects of Visual Function.

This open-label clinical trial evaluated safety and visual-function outcomes after ganglion cell-directed optogenetic therapy in 10 participants with blindness from advanced retinitis pigmentosa.

N Engl J MedOct 8, 2026Read summary
Case ReportCardiologyOpen access

Advanced Rheumatic Heart Disease Complicated by Pregnancy, Mitral Valve Disease, Pulmonary Hypertension, and Left Atrial Thrombus: A Multidisciplinary Case Report from Resource-Limited Settings.

A 27-year-old woman in late pregnancy presented with progressive dyspnea, palpitations, leg swelling, cough, and fatigue. Echocardiography showed an enlarged left atrium, moderate mitral stenosis with mild regurgitation…

Int Med Case Rep JOct 8, 2026Read case
Case ReportNeurologyOpen access

Probable vestibular paroxysmia mimicking benign paroxysmal positional vertigo of the superior semicircular canal in the presence of a neurovascular conflict: a case report and review of the literature.

A 52-year-old woman presented with positional vertigo and was initially diagnosed with right superior semicircular canal benign paroxysmal positional vertigo (BPPV).

J Med Case RepOct 7, 2026Read case
Clinical ResearchEndocrinologyOpen access

Betaine supplementation modulates mitochondrial and redox-related adaptations in premenopausal women with overweight: a randomized controlled trial.

This randomized controlled trial examined whether eight weeks of betaine supplementation (3 g/d) affected mitochondrial-associated and redox measures in premenopausal women with overweight or obesity.

Eur J NutrOct 7, 2026Read summary

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