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1998 articles

October 202624

Clinical ResearchFamily Medicine

Changes in health literacy following participation in a multidisciplinary primary care intervention for people with chronic pain: a longitudinal cohort study.

This longitudinal cohort study examined changes in health literacy among 43 people with chronic non-cancer pain who completed a personalized, multidisciplinary primary care pain-management intervention.

Scand J PainOct 6, 2026Read summary
Clinical ResearchInfectious Diseases

Efficacy and safety of switching to once-daily oral doravirine plus raltegravir in virologically suppressed people with HIV-1: a randomized, open-label, multicentre phase 2 study (DORAL).

DORAL was a multicentre, open-label, randomized phase II trial in virologically suppressed adults with HIV-1 on stable antiretroviral therapy, without prior doravirine exposure or raltegravir resistance.

J Antimicrob ChemotherOct 6, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Effectiveness of Immersive and Embodied Enhancement via "Virtual Reality" on the Sustainability of Hand Hygiene Compliance:Protocol for a Randomized Controlled Trial of a School-Based Training Program.

This protocol describes a three-arm randomized controlled trial evaluating customized virtual reality (VR) handwashing education among secondary school students in Hong Kong.

JMIR Res ProtocOct 6, 2026Read summary
Case ReportOncology (Medical)

Immune-related colitis following head and neck reconstructive surgery in a patient receiving long-term nivolumab.

A man with gastric cancer, receiving long-term nivolumab and prednisolone for immune-related myositis, underwent subtotal glossectomy for advanced tongue cancer. On postoperative day 4, he developed grade 3 diarrhoea.

BMJ Case RepOct 6, 2026Read case
Case ReportNeurosurgeryOpen access

Safe electrophysiology-guided resection of an epileptogenic non-exophytic hamartoma at the floor of the fourth ventricle in a child.

Hamartoma of the floor of fourth ventricle (HFFV) is an extremely rare entity known to be causing focal movement disorders in children.

Childs Nerv SystOct 6, 2026Read case
Case ReportGeneral Surgery

Parenchymal Injury Caused by Complete Migration of a Bone of Japanese Horse Mackerel Within the Pancreatic Uncinate Process Through a Duodenal Diverticulum, Resulting in Sepsis and Multiple Pyogenic Liver Abscesses.

A 79-year-old man developed abdominal pain and fever three days after ingesting grilled Japanese horse mackerel. Imaging revealed a fish bone fully migrated into the pancreatic uncus through a duodenal diverticulum…

Am J Case RepOct 6, 2026Read case
Clinical ResearchEndocrinologyOpen access

Cardiovascular safety in middle-aged and older men under testosterone replacement therapy: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the cardiovascular safety of testosterone replacement therapy (TRT) in middle-aged and older men, analyzing data from 31 randomized-controlled trials involving 9,437…

EndocrineOct 6, 2026Read summary
Clinical ResearchNeurologyOpen access

Associations between duration of status epilepticus and clinical outcomes in adults: a systematic review.

This systematic review examined the relationship between the duration of status epilepticus (SE) and clinical outcomes in adults, analyzing 43 studies.

J NeurolOct 6, 2026Read summary
Clinical ResearchEndocrinologyOpen access

GLP-1 receptor agonists for obstructive sleep apnea: a meta-analysis of randomized controlled trials.

This meta-analysis of randomized controlled trials evaluated the efficacy and safety of GLP-1 receptor agonists in adults with moderate-to-severe obstructive sleep apnea (OSA).

Sleep BreathOct 6, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Outcomes after middle meningeal artery embolization using coils alone for chronic subdural hematoma: A systematic review and single-arm meta-analysis.

This systematic review and single-arm meta-analysis evaluated the outcomes of coil-only middle meningeal artery embolization (MMAE) for chronic subdural hematoma (cSDH) in 397 patients across 10 studies.

Neurosurg RevOct 6, 2026Read summary
Clinical ResearchNeurologyOpen access

A Systematic Review of Stem Cell Secretome-Derived Exosomes for Neuropathic Pain: Therapeutic Mechanisms and Translational Potential.

This systematic review assessed the therapeutic mechanisms and potential of stem cell secretome-derived exosomes for neuropathic pain (NP) in preclinical and clinical studies.

Mol NeurobiolOct 6, 2026Read summary
Clinical ResearchCardiologyOpen access

Comparative efficacy and safety of orally administered PCSK9 inhibitors in patients with Hypercholesterolaemia: a dose-stratified systematic review and network meta-analysis.

This network meta-analysis evaluated the efficacy and safety of orally administered PCSK9 inhibitors in patients with hypercholesterolemia, analyzing five randomized trials with 4,227 participants.

EndocrineOct 6, 2026Read summary
Clinical ResearchPsychiatry

Reliability of Childhood Autism Rating Scale, Second Edition, Assessments Using Telepsychiatry for Children With Neurodevelopmental Disorders and Their Caregivers: Randomized Feasibility Study.

This randomized feasibility study evaluated the interrater reliability of the Childhood Autism Rating Scale, Second Edition (CARS2) between telepsychiatry and face-to-face assessments in 73 children aged 6 to 17 with…

JMIR Form ResOct 6, 2026Read summary
Clinical ResearchPsychiatry

Australian Digital Mental Health Services for Anxiety and Depression: Meta-Analysis and Comparison Study.

This meta-analysis evaluated the effectiveness and uptake of three Australian digital mental health services (DMHSs) for anxiety and depression. Over 282,000 consumers accessed these services from 2013 to 2021.

JMIR Form ResOct 6, 2026Read summary
Clinical ResearchOncology (Medical)

Efficacy and safety of MEK inhibitors for NF1-associated symptomatic, inoperable plexiform neurofibromas: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the efficacy and safety of MEK inhibitors for treating symptomatic, inoperable plexiform neurofibromas in patients with neurofibromatosis type 1 (NF1).

PLoS OneOct 6, 2026Read summary
Case ReportHematologyOpen access

Early-onset VEXAS syndrome mimicking orbital cellulitis and successfully treated with allogeneic hematopoietic stem cell transplantation.

A 25-year-old male presented with recurrent fever, weight loss, arthralgia, and symptoms resembling orbital cellulitis. Imaging revealed orbital soft tissue inflammation, while laboratory tests showed macrocytic anemia…

J HematopOct 6, 2026Read case
Clinical ResearchUrology

Immersive 3D vs Physical Simulation in Training Novices for Laser-Based Endourological Procedures: Protocol for a Randomized Controlled Trial.

This randomized controlled trial aims to compare immersive 3D simulation and physical simulation training for novice medical students in endourological laser-based procedures.

JMIR Res ProtocOct 6, 2026Read summary
Case ReportOncology (Medical)

Same-day diagnosis and robotic resection of rare primary pulmonary melanoma: a robotic bronchoscopy-guided approach.

A man in his 70s presented with a lingular pulmonary nodule suspicious for non-small cell lung cancer. He underwent robotic navigation bronchoscopy for biopsy, which was followed by robotic-assisted thoracic surgery.

BMJ Case RepOct 6, 2026Read case
Case ReportUrology

Pyelolymphatic backflow demonstrated on computed tomography urography in acute ureteric obstruction.

A man in his early 40s presented with acute right flank pain, vomiting and dysuria. Ultrasonography demonstrated an obstructing right upper ureteric calculus with a contralateral renal calculus.

BMJ Case RepOct 6, 2026Read case
Case ReportHematology

Presumed transdermal superwarfarin toxicity in a pest control worker.

A man in his early 60s presented with dyspnoea and a 2-3 month history of spontaneous mucocutaneous bleeding. Laboratory tests showed unmeasurably elevated INR and activated partial thromboplastin time.

BMJ Case RepOct 6, 2026Read case
Clinical ResearchInfectious Diseases

#aware.hiv Europe study: protocol for a stepped-wedge cluster randomised trial of a multimodal hospital-based implementation strategy targeting HIV indicator-condition-guided testing in European hospitals.

The #aware.hiv Europe study is a stepped-wedge cluster randomised trial conducted in 30 hospitals across ten European countries, aiming to improve HIV testing rates among patients with HIV indicator conditions.

BMJ OpenOct 6, 2026Read summary
Case ReportOphthalmology

Eosinophilic angiocentric fibrosis in paediatric IgG4-related disease.

A young girl presented with a 1.5-year history of progressive bilateral upper eyelid swelling and proptosis, more pronounced on the right.

BMJ Case RepOct 6, 2026Read case
Case ReportNeurology

Chronic posthypoxic myoclonus: Lance-Adams syndrome.

A man in his 20s developed chronic intentional myoclonus following two cardiac arrests, leading to persistent generalized myoclonic seizures.

BMJ Case RepOct 6, 2026Read case
Case ReportOrthopedic Surgery

Surgical and orthodontic management of class III malocclusion in monozygotic twins using bilateral sagittal split osteotomy.

This case report details the surgical and orthodontic management of class III malocclusion in identical twin sisters in their early 20s, both presenting with mandibular prognathism.

BMJ Case RepOct 6, 2026Read case

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