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1998 articles
October 202624
Duplicated spermatic cord encountered during inguinal hernia repair.
A male patient in his seventies presented for elective open right inguinal hernia repair. During the procedure, complete duplication of the spermatic cord was identified, with two distinct structures each containing a…
Approach to management of walled-off necrosis secondary to trauma-induced pancreatitis in a limited-resource setting.
A patient with trauma-induced pancreatitis developed a walled-off necrosis (WON) characterized by a necrotic peripancreatic collection. Imaging revealed a mature collection with necrotic debris.
Leveraging Longitudinal DBS Recordings to Probe Pharmacological Mechanisms: Investigating the Role of Orexin Antagonists on Extended Amygdala Activity.
A patient with severe, treatment-refractory obsessive-compulsive disorder and comorbid insomnia had beta activity recorded longitudinally from the bed nucleus of the stria terminalis (BNST) using implanted deep brain…
Randomised controlled trial of fluoxetine versus naltrexone in compulsive sexual behaviour disorder.
This randomized controlled trial compared the efficacy and tolerability of fluoxetine and naltrexone in 80 participants with compulsive sexual behaviour disorder (CSBD).
Digital Twin-Assisted Risk Disclosure in Adults Undergoing Elective Bronchoscopy: Multicenter Randomized Controlled Trial.
This multicenter randomized controlled trial evaluated the impact of digital twin-assisted risk disclosure on prebronchoscopy anxiety and postbronchoscopy satisfaction in adults undergoing elective bronchoscopy.
Amyloid PET Quantitation and Centiloid Thresholds in the Diagnosis of Alzheimer Disease: An Individual Participant Data Meta-Analysis.
This individual participant data meta-analysis examined amyloid PET scans from 49,227 participants across 53 studies to establish Centiloid positivity cutoffs for Alzheimer disease diagnosis.
Standardized Acupuncture Plus Modified Xiaoxuming Decoction for Acute Ischemic Stroke: A Randomized Controlled Trial.
This single-center, assessor-blinded randomized controlled trial enrolled adults with imaging-confirmed acute ischemic stroke within 72 hours and compared standard care with or without standardized acupuncture plus…
Acute effects of volume-matched isometric exercise intensity on vascular function and autonomic regulation in men with elevated blood pressure.
This randomized controlled trial examined the acute effects of high-intensity isometric exercise (HIIE) versus low-intensity isometric exercise (LIIE) on cardiovascular function in 17 men with elevated blood pressure.
Hepatitis A-associated oxidative haemolysis in a patient with glucose-6-phosphate dehydrogenase deficiency with co-inherited sickle cell trait.
A young male presented with pruritus, nausea, and jaundice following travel to West Africa, lacking hepatitis A vaccination.
Adamantinoma-like Ewing sarcoma of the bladder.
A patient presented with a bladder tumor initially diagnosed as urothelial carcinoma following transurethral resection. After receiving neoadjuvant chemotherapy with methotrexate, vinblastine, doxorubicin, and…
Infection burden in mismatched unrelated donor hematopoietic cell transplantation: results from the ACCESS trial.
The ACCESS trial evaluated infection burden in 268 adult patients undergoing HLA-mismatched unrelated donor hematopoietic cell transplantation (HCT) with posttransplant cyclophosphamide (PTCy) for graft-versus-host…
Severe Euglycemic Diabetic Ketoacidosis After Semaglutide-Associated Poor Intake Despite Empagliflozin Discontinuation: A Case Report.
A 68-year-old woman with long-standing type 2 diabetes developed several weeks of nausea, intermittent vomiting and diarrhea, and minimal oral intake after starting semaglutide.
Rupture of Left Ventricular Aneurysm in Infant: Case Report.
A preterm infant hospitalized from birth with necrotizing enterocolitis, later complicated by ascending-colon narrowing requiring surgery, had persistent infections with Staphylococcus haemolyticus and then…
Hernia, mesh, microbes, and phage promise: Mapping 35 years of evidence through a systematic review.
This systematic review examined published evidence on microbiology and outcomes of hernia mesh infections, including studies from 1990–2025. Of 584 studies meeting inclusion criteria, 32 contributed to meta-analysis.
Haemophagocytic lymphohistiocytosis triggered by Kikuchi-Fujimoto disease: a diagnostic challenge.
A man in his 40s presented with fever, confusion, a widespread erythematous rash, weight loss, and generalized lymphadenopathy over three weeks.
Physical activity for psychological and physical well-being in menstruating individuals: an integrative review.
This integrative review synthesised qualitative, quantitative, and mixed-methods research on physical activity and psychological or physical well-being across the menstrual cycle.
Genome-wide meta-analysis dissects the genetic basis and health implications of circulating taurine.
This genome-wide meta-analysis examined the genetic basis of circulating taurine levels in 36,490 European individuals. The study identified six common and two rare genetic loci associated with taurine levels and…
Minimally Invasive Versus Sternotomy in Redo Mitral Valve Surgery: Short- and Long-Term Outcomes with Meta-Regression and Time-to-Event Analysis.
This meta-analysis compared minimally invasive mitral valve surgery (MI-MVS) with sternotomy for redo surgery in adults. It included 15 studies and 3457 patients, pooling perioperative outcomes and reconstructing…
Preoperative CA15-3 as a predictor of axillary lymph node metastasis and prognosis in women with breast cancer: a GRADE-assessed systematic review and meta-analysis.
This GRADE-assessed systematic review and random-effects meta-analysis examined cohort studies of preoperative CA15-3 in women with breast cancer, assessing survival and metastatic outcomes.
Drug treatments for fibromyalgia: systematic review and network meta-analysis of randomised trials.
This systematic review and network meta-analysis compared drug treatments for fibromyalgia in adults, including evidence from 151 randomised trials involving 32 592 participants.
A phase III randomized study: Immunogenicity and safety of a quadrivalent meningococcal conjugate vaccine in healthy adults, adolescents, and children in India and healthy adolescents and children in South Africa.
This Phase III randomized controlled trial assessed the immunogenicity and safety of a single dose of MenACYW-TT in healthy adults, adolescents, and children in India and in adolescents and children in South Africa.
Nutraceuticals and phytoceuticals in the treatment of bipolar disorder: A systematic review and network meta-analysis.
This systematic review and network meta-analysis assessed randomized controlled trials of nutraceuticals and phytoceuticals for bipolar disorder. Twenty-eight trials involving 2,222 participants evaluated 22 treatments.
Refractory amiodarone-induced thyrotoxicosis causing malignant arrhythmias, treated with therapeutic plasma exchange-bridged thyroidectomy.
A man in his mid-60s with severe cardiomyopathy developed refractory amiodarone-induced thyrotoxicosis, leading to recurrent ventricular tachycardia.
Impact of opioid-free general anesthesia with locoregional blocks during breast cancer surgery on systemic inflammatory response: results from a randomized controlled trial.
This randomized controlled trial evaluated the effects of opioid-free general anesthesia with locoregional blocks (OfGA) versus traditional opioid-based general anesthesia (GA) on postoperative inflammation in breast…
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