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1998 articles
October 202624
Anterior Stromal Melt Following Implantation of a Large Size Corneal Allogenic Intrastromal Ring Segment (CAIRS).
To report delayed anterior stromal melt following corneal allogenic intrastromal ring segment (CAIRS) implantation in a patient without known systemic or ocular risk factors.
First-line biologic and targeted synthetic DMARDs versus methotrexate in early rheumatoid arthritis: a meta-analysis of remission outcomes.
This systematic review and meta-analysis of randomized trials compared initial biologic and targeted synthetic DMARDs (b/tsDMARDs), alone or with methotrexate, against methotrexate in methotrexate-naïve adults with…
Retrospective RNA Sequencing Reclassifies a Historical t(5;12) Eosinophilic Neoplasm From Presumed PDGFRB Rearrangement to ETV6::ACSL6.
A woman with a chronic eosinophilic myeloid neoplasm had a t(5;12) that raised suspicion of PDGFRB involvement, but contemporary testing did not identify a rearrangement and empiric imatinib produced no meaningful…
Effect of a Computer-Aided Device on Endoscopists' Biopsy Practice for Gastric Neoplasms: A Secondary Analysis of a Randomized Controlled Trial.
This secondary analysis of a randomized controlled trial compared AI-assisted with standard gastric screening, examining biopsy practice for documented lesions.
Longitudinal clinical outcomes after amyloid clearance in aducanumab phase 3 studies.
This exploratory analysis pooled participants from the randomized phase 3 ENGAGE and EMERGE aducanumab trials who entered a long-term extension or later redosing study.
Digital health interventions for psychological and cognitive care in cancer patients and caregivers: A RE-AIM-based systematic review.
This PRISMA-guided systematic review assessed the internal and external validity of digital interventions for psychological and cognitive concerns among people with cancer, caregivers, and family members, using the…
Prevalence and Predictors of Depressive Symptom Trajectories in Older Adults: A Systematic Review.
This systematic review examined longitudinal patterns of depressive symptoms and their predictors among adults aged 60 years or older.
A novel variant of pancreaticobiliary maljunction: Complete opening of the common bile duct into the duct of Santorini in a patient with pancreas divisum.
A 20-year-old woman with recurrent cholestasis and acute pancreatitis presented with fever, jaundice, and abdominal pain; laboratory findings supported cholangitis and pancreatitis.
Spontaneous splenic rupture in a patient with congenital factor XIII deficiency: A case report and literature review.
A 32-year-old man with congenital factor XIII deficiency presented with sudden abdominal pain and hypovolemic shock. Contrast-enhanced abdominal CT showed a large perisplenic hematoma, and surgery confirmed splenic…
Sutureless Epikeratophakia After Small Incision Lenticule Extraction: A Case Report to Correct Corneal Deformity.
An 18-year-old woman developed severe corneal thinning, with a residual stromal bed of 176 μm, and irregular hyperopic astigmatism in her left eye after a femtosecond laser malfunction during keratorefractive lenticule…
Trauma-related simultaneous asymmetric bilateral hip dislocation: A case report.
A 27-year-old man sustained simultaneous dislocations of both hips after high-energy trauma: the left hip was anteriorly dislocated and the right posteriorly.
Development of HOPES Intervention for a Randomized Controlled Trial to Reduce the Perceived Stigma Among Women Living With HIV/AIDS in China.
This study developed and pilot-tested HOPES, a culturally grounded WeChat program intended to reduce HIV-related stigma among Chinese women living with HIV/AIDS.
National and Subnational Trends in Ischemic Heart Disease Burden in Iran, 1990-2023: A Systematic Review.
This systematic review synthesized national and subnational evidence on ischemic heart disease (IHD) in Iran from 1990 to 2023, including model-based estimates and empirical studies.
Efficacy and Safety of Traditional Chinese Medicine in Treating Chronic Obstructive Pulmonary Disease with Osteoporosis: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the efficacy and safety of traditional Chinese medicine (TCM) as an adjunct to conventional treatment for chronic obstructive pulmonary disease (COPD) with osteoporosis…
The Acceptability and Experiences of Participating in a Preoperative Intentional Weight-Loss Programme From Diagnosis to Surgery for Colorectal Cancer.
This qualitative study, embedded in the CARE randomised controlled trial, explored how patients with colorectal cancer experienced an intensive, dietitian-supported weight-loss programme between diagnosis and surgery.
NIHSS and Large Artery Atherosclerosis Affect Efficacy of Dual Antiplatelet Therapy Versus Alteplase for Minor Stroke.
This randomized controlled trial analyzed the efficacy of dual antiplatelet therapy (DAPT) versus alteplase in patients with minor stroke (NIHSS 0-5) and assessed the impact of large artery atherosclerosis (LAA).
Effectiveness of a Sodium Intake Monitoring Smartphone Application (NamakBan) on Clinical Outcomes of Patients Diagnosed With Hypertension: A Randomized Clinical Trial.
This randomized clinical trial evaluated the effectiveness of the NamakBan smartphone application for monitoring sodium intake in 88 adults with primary hypertension.
A systematic review and meta-analysis of preoperative MRI-based pelvimetry in predicting surgical difficulty in rectal cancer: Implications for personalised surgical planning.
This systematic review and meta-analysis evaluated the role of MRI-based pelvimetry in predicting surgical difficulty during total mesorectal excision (TME) for rectal cancer, involving 8,364 patients across 36 studies.
Effects of Estriol-Lactobacilli Combination Versus Polycarbophil-Based Vaginal Moisturizer on Post-Radiation Vaginitis in Women With Cervical Cancer: A Randomized Controlled Trial.
This randomized controlled trial evaluated the efficacy of an estriol-lactobacilli combination vaginal tablet (E3/L) versus a polycarbophil-based vaginal moisturizer (PBVM) in 34 women with post-radiation vaginitis…
Topical Anesthetics Effectiveness in Management of Orthodontic Pain: A Systematic Review of Randomized Controlled Trials.
This systematic review evaluated the effectiveness of topical anesthetics in managing orthodontic pain, analyzing nine randomized controlled trials involving 456 participants aged 14-35.
Temporal Patterns of Outcomes After DMARD Tapering or Withdrawal in Rheumatoid Arthritis With Sustained Disease Control: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the effects of DMARD tapering and withdrawal in patients with rheumatoid arthritis (RA) who had sustained disease control.
Continuous Renal Replacement Therapy for Cytokine Storm in Diabetic Kawasaki Shock Syndrome.
A 3-year, 10-month-old boy with poorly controlled type 1 diabetes and autoimmune thyroiditis presented with Kawasaki disease shock syndrome and diabetic ketoacidosis.
A Novel FAM111A Frameshift Variant Associated With Osteoclast Necroptosis and KCS2-like Syndrome.
Kenny-Caffey syndrome type II (KCS2) is a rare genetic disorder characterized by skeletal abnormalities, impaired growth, and developmental delay.
Online stepped care for the treatment of posttraumatic stress disorder: A randomized controlled noninferiority trial.
This randomized controlled non-inferiority trial compared online stepped care with telehealth cognitive processing therapy (CPT) in 84 adults with PTSD or subthreshold PTSD.
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