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1998 articles
October 202624
Pediatric Brain Tumor Consortium Phase I Study of CD40 Agonist Sotigalimab in Pediatric and Young Adult Patients with Recurrent CNS Tumors and Newly Diagnosed DIPG.
The PBTC-051 study evaluated the safety and preliminary efficacy of the CD40 agonist sotigalimab in 31 pediatric and young adult patients with recurrent CNS tumors and newly diagnosed DIPG.
Investigation of a Prostate Cancer Radiation Response Signature in the Breast Cancer SweBCG91RT Randomized Trial.
This randomized controlled trial evaluated the Prostate cancer Radiation Therapy Outcomes Score (PORTOS) in predicting radiotherapy benefit in 765 patients with early-stage breast cancer.
Molecular Profiling of Tisotumab Vedotin-Treated Patients Identifies Immune Pathways Associated with Clinical Activity.
This phase II multicenter trial evaluated the efficacy of tisotumab vedotin (TV) in patients with recurrent or metastatic cervical cancer (r/mCC).
A Phase I Study of PF-07062119, an Anti-GUCY2C/Anti-CD3 Bispecific Fc Antibody, in Patients with Advanced Gastrointestinal Cancers.
This Phase I multicenter study evaluated PF-07062119, an anti-GUCY2C/anti-CD3 bispecific antibody, in 79 patients with advanced gastrointestinal cancers.
Clinical Trial Protocol for LPS-Boost: Intensified [ 177 Lu]Lu-PSMA-617 Treatment for Patients with Metastatic Castration-Resistant Prostate Cancer with Low PSMA-Expressing Disease.
This multicenter, open-label phase 2 trial investigates an intensified treatment schedule of [177Lu]Lu-PSMA-617 for 45 patients with metastatic castration-resistant prostate cancer (mCRPC) and low PSMA expression.
Tumor and Organ Dose Estimates from 177 Lu-PSMA-617 Therapy in Patients with Metastatic Castration-Resistant Prostate Cancer: Results from the RESIST-PC Phase 2 Trial.
The RESIST-PC Phase 2 trial assessed dosimetry of [177Lu]Lu-PSMA-617 in patients with metastatic castration-resistant prostate cancer. A total of 48 patients were analyzed, receiving either 6.0 or 7.4 GBq per cycle.
Maxillofacial prosthetic management of oral incompetence following commando surgery and partial maxillectomy: A clinical report.
A patient who underwent commando surgery and partial maxillectomy for squamous cell carcinoma presented with significant facial defects, oral incompetence, and discomfort.
Long-Term Safety and Efficacy of Dazukibart in Dermatomyositis: Combined Phase II Results From Double-Blind and Open-Label Extension Studies.
This study evaluated the long-term safety and efficacy of dazukibart, an antiinterferon β monoclonal antibody, in adults with moderate-to-severe dermatomyositis through a combined Phase II randomized controlled trial…
A 6-Year-Old With Becker Muscular Dystrophy and Catatonia.
A 6-year-old boy presented with acute behavioral changes suggestive of catatonia, including altered speech and awareness. He was found to have previously undiagnosed Becker muscular dystrophy.
Primary tongue leiomyosarcoma.
A male patient in his mid 50s presented with a non-healing ulcer on the right lateral border of the tongue, accompanied by impaired tongue movement.
The Duke CSF-Venous Fistula Confidence Score: Real-World Application on CT Myelography.
A case of a patient with spontaneous intracranial hypotension was evaluated using CT myelography to identify a suspected CSF-venous fistula (CVF).
Low-Dose Cytarabine Plus G-CSF Induction in Pediatric M2 Acute Myeloid Leukemia: A Multicenter Study.
This multicenter randomized controlled trial analyzed the efficacy and safety of low-dose chemotherapy (LDC) versus standard-dose chemotherapy (SDC) in 221 children with M2 acute myeloid leukemia.
The role of vitamin D signalling in β cell apoptosis: a systematic review.
This systematic review examined the role of vitamin D signalling in pancreatic β-cell apoptosis, analyzing 26 studies across various models.
MicroRNAs Regulation of Axon Sprouting in Peripheral Nerve Regeneration: A Systematic Review.
This systematic review examines the role of microRNAs (miRNAs) in peripheral nerve regeneration, focusing on miR-21, miR-133b, miR-124, and miR-30b.
Resolution of restless legs syndrome after postdilution online hemodiafiltration using a vitamin E-bonded polysulfone membrane: a report of two cases.
Two patients with long-standing, refractory restless legs syndrome underwent high-efficiency online hemodiafiltration but did not achieve sufficient symptom relief.
A Systematic Review and Meta-Analysis of the Role of Ultrasonography for the Diagnosis of Vesicoureteral Reflux in Pediatric Patients Following Urinary Tract Infections: Technical Report.
This systematic review and meta-analysis evaluated the diagnostic accuracy of renal and bladder ultrasonography (RBUS) for detecting vesicoureteral reflux (VUR) in pediatric patients post-urinary tract infection (UTI).
Oral peri-implant tissue as a neoplastic bed: a systematic review of clinicopathology, pathogenesis, and survival outcomes.
This systematic review assessed the clinicopathology, associated factors, and survival outcomes of histologically confirmed neoplasms adjacent to dental implants.
Apheresis-Triggered Torsades De Pointes in Congenital Long QT Syndrome Type 2: Citrate-Related Arrhythmia Risk and Safe Modality Switching During Myasthenic Crisis.
A 44-year-old woman with congenital long QT syndrome Type 2 presented in myasthenic crisis due to anti-MuSK-positive myasthenia gravis.
Negative affect influences the computations underlying food choice in bulimia nervosa.
This randomized controlled trial examined how negative affect influences food choice dynamics in 25 women with bulimia nervosa (BN) and 21 healthy controls.
Dose Considerations and Generalization Following Script Training for Poststroke Aphasia: A Randomized Factorial Clinical Trial.
This single-site, single-blind, 2 × 2 factorial randomized controlled trial examined how script length and session frequency affect treatment outcomes in 85 people with chronic poststroke aphasia.
Remote robotic urological surgery with the Toumai® System across 25-7,000 km: a systematic review and single-arm meta-analysis of technical success and reported safety.
To summarize the early clinical experience with the Toumai ® robotic system in remote urological surgery and to descriptively synthesize technical success, perioperative outcomes, and network performance, while…
Neural correlates of acute task-related stress in humans: a systematic review and coordinate-based ALE meta-analysis.
This systematic review and ALE meta-analysis examined the neural correlates of acute task-related stress using task-based fMRI studies.
Efficacy of nebulized salbutamol in transient tachypnea of the newborn: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy of nebulized salbutamol in improving clinical outcomes for infants with transient tachypnea of the newborn (TTN).
Clinical Reasoning: A 13-Year-Old Boy With Acute-Onset Generalized Dystonia, Rostrocaudal Gradient, and Severe Bulbar Dysfunction.
A 13-year-old boy presented with acute-onset generalized dystonia, characterized by progressive slowness, speech loss, dysphagia, rigidity, and dystonic posturing over a month.
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