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1999 articles
October 202624
A Composite Ovine Forestomach Matrix and Hyaluronic Acid CAMP for the Treatment of Full Thickness Wounds of the Foot in People With Diabetes: A Randomized Controlled Trial.
This randomized controlled trial evaluated the efficacy of a novel composite CAMP, OFM-HA, in treating full thickness diabetic foot ulcers (DFUs) in 143 patients.
Association of HRD Score With Efficacy of Neoadjuvant Short-Course Radiotherapy Plus Sequential Chemoimmunotherapy in pMMR Locally Advanced Rectal Cancer.
This Phase II clinical trial examined the relationship between homologous recombination deficiency (HRD) score and treatment response in 32 patients with mismatch repair-proficient locally advanced rectal cancer…
Portable Dynamometry Is Reliable for Measuring Knee and Ankle Strength in Daily Practice: Results From a Systematic Review With Meta-analysis and Evidence Gap Map Using the COSMIN Methodology.
This systematic review and meta-analysis evaluated the reliability and criterion validity of portable dynamometers for measuring knee and ankle muscle strength in both uninjured individuals and those with lower-limb…
Factors affecting the experience of procedural and postoperative pain in children and adolescents - a systematic review.
This systematic review examined factors influencing procedural and postoperative pain in children and adolescents aged 3-18 years.
Evaluating plasma ferritin and suPAR as treatable traits for critically ill patients with COVID-19 treated with anakinra: an exploratory analysis of the immune modulation domain of the REMAP-CAP randomised clinical trial.
This exploratory analysis of the REMAP-CAP randomized clinical trial evaluated plasma ferritin and suPAR as potential treatable traits for anakinra in critically ill COVID-19 patients.
Factors influencing access to green health prescribing in primary care for older adults - a qualitative systematic review.
This systematic review examined barriers and enablers to green health prescribing (GHP) for older adults with long-term conditions.
Xiaoaiping Injection Combined with Chemotherapy Versus Chemotherapy Alone for Breast Cancer: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed the efficacy and safety of Xiaoaiping Injection (XAP) combined with chemotherapy versus chemotherapy alone in breast cancer patients.
Opioid-Sparing Analgesia After Laparoscopic Gastrectomy: Exploratory Clinical Outcomes and Cine-MRI Assessment of Small-Bowel Motility.
This randomized controlled trial evaluated opioid-sparing multimodal analgesia versus conventional opioid analgesia in 130 patients undergoing laparoscopic radical gastrectomy.
Use of a Synthetic Polylactic Acid Matrix for Pyoderma Gangrenosum: A Case Series.
This case series involved six patients with chronic, non-healing ulcers due to pyoderma gangrenosum, persisting for 6 months to 3 years.
Perioperative Management of an Implanted Spinal Cord Stimulator: A Problem-Based Learning Discussion.
A patient with an implanted spinal cord stimulator (SCS) was scheduled for elective surgery. The case highlighted critical aspects of perioperative management, including the identification of the device, potential…
Age at Iatrogenic Menopause and Cardiovascular Morbidity and Mortality: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the cardiovascular morbidity and mortality associated with iatrogenic menopause in 2,617,942 women.
Pediatric Spinal Cord Astrocytoma With Granular Cell-Like Morphology and KIAA1549::BRAF Fusion.
A pediatric patient presented with a spinal cord tumor exhibiting prominent granular cell-like features, complicating the initial diagnosis.
Bilateral Costoclavicular Brachial Plexus Block for Closed Reduction of Bilateral Elbow Dislocation: A Case Report and Review of the Literature.
A 60-year-old man presented with bilateral posterolateral elbow dislocation following a road traffic accident. He underwent closed reduction and cast application under a bilateral ultrasound-guided costoclavicular…
Spread and Sustainability of an Antimicrobial Stewardship Initiative Within a Pediatric Network.
This randomized controlled trial evaluated the sustainability of an antimicrobial stewardship initiative in a pediatric network, focusing on prescribing practices for skin and soft tissue infections (SSTI).
Biologics and Small-Molecule Inhibitors for the Treatment of Nummular Eczema: A Systematic Review.
This systematic review evaluated the efficacy of biologics and small-molecule inhibitors for treating nummular eczema (NE) by analyzing 10 studies.
Chatbot Intervention and Cancer Risk Knowledge in Adolescents and Young Adults With Cancer Predisposition: A Randomized Clinical Trial.
This multicentre randomized clinical trial evaluated whether a tailored electronic chatbot improved cancer-risk understanding among English-speaking adolescents and young adults aged 12 to 24 years with one of nine…
INDIVIDUAL ARTICLE: Tildrakizumab for Real-World Psoriasis Care: Clinical Lessons From Medically Complex and Underserved Patient Populations.
This case review discusses 16 patients with moderate-to-severe plaque psoriasis treated with tildrakizumab, a monoclonal antibody targeting interleukin-23.
Cicatricial Ectropion in the Setting of IL-13 Inhibition.
An 81-year-old man with extensive atopic dermatitis was treated with dupilumab, leading to significant improvement. However, he later developed ocular symptoms and inferior cicatricial ectropion of the left lower eyelid.
Exceptional and Durable Response to Selpercatinib in a Patient with Apparently RET -Negative, HRAS -, and NF1 -Mutated Metastatic Medullary Thyroid Carcinoma.
A 50-year-old woman presented with rapidly progressive medullary thyroid carcinoma (Ki-67 30%) and extensive liver and bone metastases.
Systematic Review: Inclusion of Patients With Difficult-to-Treat Inflammatory Bowel Disease in Randomized Controlled Trials of Advanced Therapies.
This systematic review examined how patients with difficult-to-treat inflammatory bowel disease (DTT-IBD) were represented in randomized controlled trials of advanced therapies for ulcerative colitis and Crohn’s…
Effects of Yoga on Rheumatoid Arthritis: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the effects of yoga on psychological function and inflammation in individuals with rheumatoid arthritis (RA).
Davos@home: Integrating objective home monitoring into eHealth self-management support after alpine altitude climate treatment for severe asthma.
This 12-month pragmatic randomised trial assessed whether objective home monitoring adds benefit to eHealth self-management after Alpine Altitude Climate Treatment (AACT) in adults with severe asthma.
Pulsed Dye Laser for Sensory Dysesthesias Associated With Chronic Radiation Dermatitis.
Two breast cancer patients with chronic radiation dermatitis (CRD) presented with debilitating sensory dysesthesias unresponsive to conventional treatments.
Clinical trial: The Effect on Intragastric pH and Pharmacokinetics of the PCAB Linaprazan Glurate in Healthy Subjects After Repeat-Dose Administration for up to 14 Days.
This open, randomised, parallel-group Phase 1 trial assessed intragastric pH and pharmacokinetics after single and repeated linaprazan glurate (LG) dosing in 73 healthy subjects.
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