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1999 articles
September 202624
Short-term nasal decongestant as bridge therapy with intranasal corticosteroids in children with persistent allergic rhinitis: A randomized controlled trial.
This prospective, open-label, single-centre randomised trial compared intranasal corticosteroid (INS) alone with INS plus five days of oxymetazoline in children aged 4–17 years with moderate-to-severe persistent…
Total Left Main Occlusion ST-Elevation Myocardial Infarction Complicated by Cardiogenic Shock and Delayed Sinus Node Dysfunction.
A 58-year-old man presented with severe chest pain due to an extensive anterolateral STEMI caused by total occlusion of the left main coronary artery.
Neurosyphilis Concurrently Presenting With Limbic Encephalitis and Normal Pressure Hydrocephalus: A Case Report.
A 47-year-old man presented with cognitive decline, gait disturbance, and urinary incontinence. Imaging revealed ventricular enlargement and high signal intensity in the medial temporal lobes.
Scleromyxedema-Associated Myopathy and Vacuolar Myopathy with Monoclonal Gammopathy and Stiffness (VAMMGAS) as manifestations of Monoclonal Gammopathy of Clinical Significance (MGCS): a disease spectrum between autophagy dysfunction and inflammation.
This report discusses two patients with Scleromyxedema-Associated Myopathy (SAM) and one with Vacuolar Myopathy with Monoclonal Gammopathy and Stiffness (VAMMGAS), both associated with Monoclonal Gammopathy of Clinical…
Occipitocervical fusion and decompression in Morquio syndrome: a case report and literature review.
A 10-year-old girl with Morquio syndrome presented with progressive quadriparesis due to severe cervical myelopathy. She underwent occipitocervical decompression and fusion, which led to significant neurological…
Acceptability and Feasibility of a Virtual Family-Based Single-Session Intervention for Young Teens at High Risk for Substance Use Disorder: Single-Arm Pilot Trial.
This single-arm pilot trial evaluated a virtual family-based single-session intervention (SSI) for young teens aged 12-14 at high risk for substance use disorder (SUD).
Systolic blood pressure targets after successful endovascular thrombectomy: a network meta-analysis of randomized controlled trials.
This network meta-analysis evaluated the impact of different systolic blood pressure (SBP) targets on outcomes after endovascular thrombectomy in eight studies.
Blood Pressure Dipping Status in Chronic Kidney Disease and Association With Adverse Outcomes: A Systematic Review and Meta-Analysis.
This systematic review and random-effects meta-analysis examined nondipping blood pressure prevalence, its association with CKD, and outcomes among people with CKD.
Prevalence of Cerebellar Cognitive Affective Syndrome in Patients with Cerebellar Disorders: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the prevalence of cerebellar cognitive affective syndrome (CCAS) in patients with cerebellar disorders.
Metastatic dedifferentiated malignant melanoma with spindle cell morphology.
A man in his early 60s presented with a slow-growing skin lesion on his back, which had been present for two decades, and a newly noticed right axillary mass.
Crohn's disease unmasks pulmonary sarcoidosis on biologic screening: dual granulomatous pathology responsive to infliximab.
A man in his 30s with a history of ileal Crohn's disease was diagnosed with pulmonary sarcoidosis during routine pre-biologic screening, despite being asymptomatic.
Autologous Hematopoietic Transplantation Reduces Brain Inflammatory and Axoglial Damage Biomarkers in Multiple Sclerosis.
This Phase II multicenter clinical trial investigated the effects of autologous hematopoietic stem cell transplantation (AHSCT) on inflammatory and axoglial damage biomarkers in 24 patients with severe multiple…
Pain outcomes and safety in trigeminal neuralgia: a systematic review and meta-analysis comparing percutaneous balloon compression with microvascular decompression.
This systematic review and meta-analysis evaluated the efficacy and safety of percutaneous balloon compression (PBC) versus microvascular decompression (MVD) in treating trigeminal neuralgia (TN) among 1284 patients.
Localised cutaneous leishmaniasis in an immunosuppressed host: the role for adjuvant photodynamic therapy after incomplete amphotericin B response.
An immunocompromised man in his 70s presented with a 15-year verrucous plaque on the right hallux, initially misdiagnosed as squamous cell carcinoma.
Sacituzumab tirumotecan in previously treated metastatic triple-negative breast cancer: a detailed safety analysis of the randomized OptiTROP-Breast01 study.
This randomized controlled trial analyzed the safety profile of sacituzumab tirumotecan (sac-TMT) in 262 patients with previously treated metastatic triple-negative breast cancer.
Primary adrenal lymphoma presenting as primary adrenal insufficiency.
A man in his late 60s presented with symptoms of adrenal failure, including anaemia and hypercalcaemia. Initial tests indicated adrenal insufficiency, and imaging showed bilateral adrenal enlargement.
Unlocking the airway through mandibular distraction followed by TMJ release in bilateral TMJ ankylosis complicated by severe OSA.
An early adolescent with bilateral TMJ ankylosis presented with severe obstructive sleep apnoea (OSA), facial asymmetry, and a limited mouth opening of 2 mm.
Treat-to-target strategies for low-density lipoprotein cholesterol and triglyceride levels for primary and secondary prevention of cardiovascular disease in adults with dyslipidaemia.
This Cochrane systematic review protocol aims to assess the effectiveness of treat-to-target strategies for managing low-density lipoprotein cholesterol and triglyceride levels in adults with dyslipidaemia.
Prevalence and risk factors for road traffic accidents and mortalities in the Amhara region, Ethiopia: a systematic review and meta-analysis.
This systematic review and meta-analysis examined the prevalence and risk factors of road traffic accidents in the Amhara region of Ethiopia, analyzing data from 12 studies involving 5,222 participants.
False Passage During Single-Lung Ventilation in a Tracheostomized Patient: Intraoperative Recognition and Rescue.
A 63-year-old man with a recent tracheostomy due to cervical cellulitis underwent urgent thoracotomy for mediastinal debridement.
Delayed cardiac conduction disease in a young adult following childhood Chagas infection.
A Bolivian man in his 30s presented to the emergency department with non-exertional chest pain and intermittent second-degree atrioventricular block.
Responder analysis of adaptive postural balance cardiac rehabilitation exercise in patients with coronary artery disease and type 2 diabetes: secondary analysis of a randomized trial.
This secondary analysis of a randomized trial evaluated the effects of adaptive postural balance cardiac rehabilitation exercise (APBCRE) versus aerobic exercise (AE) in 167 patients with coronary artery disease and…
Effects of natriuresis-guided diuretic therapy in men and women with acute heart failure: insights from PUSH-AHF.
This exploratory sex-specific analysis of the multicentre randomised PUSH-AHF trial examined natriuresis-guided diuretic therapy versus standard care in 310 patients with acute heart failure, 45% of whom were women.
Population Pharmacokinetics and Exposure-response Analysis of Durvalumab in Patients with Limited-stage Small-cell Lung Cancer in the Phase 3 ADRIATIC Study.
The ADRIATIC study evaluated the population pharmacokinetics and exposure-response relationships of durvalumab in patients with limited-stage small-cell lung cancer (LS-SCLC).
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