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1998 articles

October 202624

Clinical ResearchInfectious DiseasesOpen access

Sevuparin in children with severe malaria: a phase I safety and dose-finding trial.

This phase I dose-finding trial assessed sevuparin safety and tolerability in Kenyan and Zambian children with severe malaria.

Nat CommunOct 21, 2026Read summary
Case ReportPathology (Anatomic & Clinical)Open access

Co-occurrence of aortic dissection and polycystic kidney disease: a case report.

A 19-year-old Caucasian man with no known medical history collapsed during sexual intercourse and died. Post-mortem examination found hemopericardium and aortic dissection in association with polycystic kidney disease…

J Med Case RepOct 21, 2026Read case
Clinical ResearchObstetrics & GynecologyOpen access

The effects of perinatal depression and anxiety on memory, attention, and cognitive flexibility: a systematic review and meta-analysis.

This systematic review and meta-analysis examined whether perinatal depressive and anxiety symptoms are associated with memory, attention, and cognitive flexibility.

Arch Womens Ment HealthOct 21, 2026Read summary
Clinical ResearchPreventive Medicine / Public HealthOpen access

Evaluating a multi-vaccine respiratory immunization strategy involving SARS-CoV-2, pneumococcal, and influenza vaccines in adults: A randomized, open-label, multicenter, controlled, non-inferiority Phase IV trial in China.

This randomized, open-label, multicenter Phase IV trial in China assessed immunogenicity and safety when adults aged ≥18 years received an inactivated SARS-CoV-2 vaccine with PPV23 and IIV4, compared with separate…

Hum Vaccin ImmunotherOct 21, 2026Read summary
Case ReportDermatology

5-Aminolevulinic acid-based photodynamic therapy used as a long-term management approach for refractory lichen sclerosus.

A 37-year-old man with more than 10 years of genital lichen sclerosus had recurrence after surgical resection, which left permanent anatomical deformity.

J Dermatolog TreatOct 21, 2026Read case
Case ReportOphthalmology

METASTATIC UROTHELIAL CARCINOMA OF THE BLADDER TO THE RETINA: A CLINICOPATHOLOGIC CORRELATION AND REVIEW OF THE LITERATURE.

A patient with urothelial carcinoma of the bladder had a large yellow-white lesion in the superotemporal retina of the left eye.

RetinaOct 21, 2026Read case
Clinical ResearchRheumatologyOpen access

Association between rheumatic diseases and glaucoma risk: a systematic review and meta-analysis of 5.7 million individuals.

This systematic review and meta-analysis examined glaucoma occurrence and risk among people with rheumatic diseases (RD), drawing on 18 studies with 5,766,143 participants.

Int OphthalmolOct 21, 2026Read summary
Case ReportGeneral Surgery

Duplicated Appendix With Mucocele Mimicking an Appendiceal Neoplasm in a 45-Year-Old Woman: A Case Report.

A 45-year-old woman with right lower-quadrant pain and fever had CT evidence of ruptured appendicitis with a loculated peri-appendiceal abscess, which improved after percutaneous drainage and intravenous antibiotics.

Am J Case RepOct 21, 2026Read case
Clinical ResearchPsychiatry

Semaglutide modulates explore/exploit decision-making in major depressive disorder: A randomized clinical trial.

This secondary analysis of a randomized clinical trial examined whether semaglutide affected explore/exploit decision-making in 72 participants with major depressive disorder (MDD).

Psychol MedOct 21, 2026Read summary
Clinical ResearchOphthalmology

EVALUATING THE EFFICACY AND SAFETY OF TOPICAL DIFLUPREDNATE IN PATIENTS WITH CHRONIC CENTRAL SEROUS CHORIORETINOPATHY.

This pilot, open-label randomized controlled trial compared topical difluprednate, oral eplerenone, and observation in adults with chronic or relapsing central serous chorioretinopathy.

RetinaOct 21, 2026Read summary
Case ReportDermatologyOpen access

Blood, ink, and flies: A case report on the house fly (Musca domestica) feeding on active tattooing wounds.

During a tattoo session, a healthy 32-year-old man in Germany experienced repeated landing and feeding attempts by house flies on freshly wounded skin of his right lower leg.

Parasitol ResOct 21, 2026Read case
Clinical ResearchCardiologyOpen access

Effectiveness and safety of atorvastatin/ ezetimibe fixed-dose combination in hypercholesterolemia: a systematic review and network meta-analysis.

This systematic review and network meta-analysis compared atorvastatin alone with atorvastatin/ezetimibe free-equivalent and fixed-dose combinations in people with hypercholesterolemia.

PeerJOct 21, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Systematic review and meta-analysis of mesh versus suture repairs of small umbilical hernias (≤ 2 cm).

This systematic review and meta-analysis compared mesh with suture repair for small umbilical hernias (defects ≤ 2 cm). The primary outcome was postoperative recurrence; secondary outcomes included complications and…

HerniaOct 21, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Feasibility and safety of an exercise-based prehabilitation intervention before cancer surgery: a pilot randomised controlled trial.

This single-centre pilot randomised controlled trial assessed the feasibility and safety of supervised aerobic prehabilitation before surgery in patients with breast, colorectal, or prostate cancer.

Support Care CancerOct 21, 2026Read summary
Clinical ResearchGeriatricsOpen access

Thermographic outcomes of auricular laser acupuncture and auricular seed acupressure in older adults with chronic shoulder pain: an exploratory nonrandomized, nonconcurrent comparison.

This exploratory, open-label, nonrandomized comparison studied 20 adults aged 60–90 years with chronic shoulder pain, allocated by order of entry to auricular laser acupuncture or seed acupressure.

Lasers Med SciOct 21, 2026Read summary
Clinical ResearchOrthopedic Surgery

Additional Functional Exercise Training Improves Knee Recovery After Meniscus Repair: A Randomized Controlled Trial.

This prospective randomized controlled trial assessed whether functional exercise training (FET) added to conventional rehabilitation improves recovery after meniscus repair.

J Vis ExpOct 21, 2026Read summary
Clinical ResearchGastroenterology

Effects of Aerobic Exercise on Autonomic and Endothelial Function and Splanchnic Hemodynamics in Compensated Cirrhosis: RCT Study.

This parallel-group randomised controlled trial assessed 16 weeks of moderate-intensity aerobic exercise plus nutritional consultation versus nutritional consultation alone in 50 sedentary patients with compensated…

Liver IntOct 21, 2026Read summary
Case ReportPhysical Medicine & Rehabilitation

Seated Modified Liuzijue Training for Rehabilitation of a Patient with Respiratory Impairment During the Recovery Phase of Stroke: A Case Report.

A patient with respiratory impairment during stroke recovery also had motor dysfunction and balance limitations that made the traditional standing Liuzijue protocol unsuitable.

J Vis ExpOct 21, 2026Read case
Clinical ResearchEndocrinology

The Effect of Obesity on the α-Cell Response to Hyperglycemia in the Presence of Amino Acids.

This randomized, two-occasion study examined how amino acids affect glucagon suppression during graded glucose infusion in lean participants and participants with obesity, with or without hepatic steatosis.

DiabetesOct 21, 2026Read summary
Case ReportMedical GeneticsOpen access

Clinically isolated hearing loss as a mild phenotype of PEX26-associated peroxisomal biogenesis disorder: A case report, literature review, and in silico analysis.

An Iranian man presented with bilateral sensorineural hearing loss (SNHL) and no other clinical manifestations at evaluation.

Mol Biol RepOct 21, 2026Read case
Clinical ResearchEndocrinology

Evaluating Improvement in Pain and Sensory Function When Using High-Frequency (10-kHz) Spinal Cord Stimulation in Individuals With Painful Diabetic Neuropathy: A Multicenter Randomized Controlled Trial (PDN-Sensory).

The multicenter randomized controlled PDN-Sensory trial evaluated 10-kHz spinal cord stimulation (SCS) plus conventional medical management (CMM) versus CMM alone in people with painful diabetic neuropathy.

Diabetes CareOct 21, 2026Read summary
Clinical ResearchOphthalmology

ULTRAWIDE-FIELD COLOR FUNDUS IMAGES AND ARTIFICIAL INTELLIGENCE FOR DIAGNOSIS OF DIABETIC RETINOPATHY: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed artificial intelligence (AI) for diabetic retinopathy (DR) evaluation using ultrawide-field fundus images.

RetinaOct 21, 2026Read summary
Clinical ResearchPulmonology

Interventions to increase participation in lung cancer screening programmes: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed interventions to improve informed choice and participation in low-dose CT lung cancer screening.

Eur Respir RevOct 21, 2026Read summary
Clinical ResearchRheumatology

Calorie-Restricted DASH, Carbohydrate-Restricted, and Low-Purine Diets for Weight Loss and Urate Control in Men With Overweight or Obesity and Hyperuricemia: A Randomized Trial.

This 12-week, open-label, active-comparator randomized trial compared calorie-restricted carbohydrate-restricted, DASH, and low-purine balanced diets in 102 men with overweight or obesity and hyperuricemia.

Diabetes CareOct 21, 2026Read summary

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