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1999 articles

September 202624

Case ReportGeriatrics

Electrical Impedance Tomography-Guided Precision Nursing in an Older Patient With Septic Shock and ARDS: A Case Report.

A 79-year-old patient with septic shock, ARDS, and MODS underwent precision nursing management utilizing electrical impedance tomography (EIT).

Nurs Crit CareSep 26, 2026Read case
Case ReportPathology (Anatomic & Clinical)

Somatic PIK3CA and PTEN mutations with endothelial PI3K/AKT/mTOR activation in RAS-negative brain arteriovenous malformations.

This report details two autopsy-confirmed brain arteriovenous malformations (bAVMs) with somatic PIK3CA mutations, one of which also had a PTEN alteration.

J Neuropathol Exp NeurolSep 26, 2026Read case
Clinical ResearchHematology

Carfilzomib plus induction chemotherapy for children with relapsed or refractory acute lymphoblastic leukemia.

This phase II clinical trial evaluated the efficacy of carfilzomib combined with induction chemotherapy (CFZ-VXLD) in pediatric patients aged 1 month to <21 years with relapsed or refractory acute lymphoblastic leukemia…

Blood AdvSep 26, 2026Read summary
Clinical ResearchOncology (Medical)

Molecular biomarkers as key determinants of outcome in mantle cell lymphoma: results from the FIL V-RBAC trial.

This phase II clinical trial analyzed the molecular landscape of 132 older patients with mantle cell lymphoma (MCL) from the FIL V-RBAC trial.

Blood AdvSep 26, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Diagnostic Strategies After Negative Colposcopy in High-Grade Cervical Cytology: A Multicenter Randomized Trial.

This multicenter randomized trial evaluated diagnostic strategies for detecting HSIL+ in women with high-grade cervical cytology and negative colposcopy.

J Low Genit Tract DisSep 26, 2026Read summary
Case ReportNeurology

Biomarker-Guided Diagnosis of Riboflavin Transporter Deficiency Presenting as Seronegative Myasthenia Gravis: A Short Report from a Consanguineous Family.

A 3.5-year-old girl born to consanguineous parents developed bilateral ptosis, followed by dysphagia, dysphonia, facial diplegia, stridor, and respiratory compromise.

Genet Test Mol BiomarkersSep 26, 2026Read case
Clinical ResearchPulmonology

Early cardiovascular vulnerability after acute exacerbation of COPD: a time-windowed systematic review and evidence map.

This systematic review and evidence map examined cardiovascular events during and after exacerbations of COPD, asthma, or bronchiectasis, with COPD as the primary evidence base.

Respir MedSep 26, 2026Read summary
Clinical ResearchGastroenterology

Quantifying Pancreatic Fat Using a Free-Breathing Acquisition in Adults With Obesity Undergoing Diet-Induced Weight Loss-Results From the LION Study.

This randomized controlled trial evaluated a free-breathing six-echo radial stack-of-stars acquisition for quantifying pancreatic fat in 18 adults with obesity undergoing diet-induced weight loss.

NMR BiomedSep 26, 2026Read summary
Clinical ResearchNeurology

Single-Area Versus Multiple-Area Passive Recharge Burst During Spinal Cord Stimulator Trials: An Independent Prospective Randomized, Double-Blind Study.

This randomized controlled trial evaluated the effectiveness of single-area versus multi-area passive recharge burst therapy in a neurostimulation naive population for chronic pain management.

Pain PractSep 26, 2026Read summary
Clinical ResearchEndocrinology

Empagliflozin Promotes Natriuresis in Diabetic Patients with Cirrhotic Refractory Ascites: A Proof-of-Concept Study.

This randomized controlled trial investigated the effects of empagliflozin on natriuresis in 21 diabetic patients with decompensated cirrhosis and refractory ascites.

J Gastrointestin Liver DisSep 26, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Effectiveness of Lactobacillus-supplemented eradication therapy for Helicobacter pylori: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis evaluated the effectiveness of Lactobacillus-supplemented Helicobacter pylori eradication therapy across 32 randomized controlled trials involving 4,010 patients.

Eur J Clin PharmacolSep 26, 2026Read summary
Clinical ResearchGeriatrics

Does Dosage Drive Durability? A Longitudinal Study on Digital Cognitive Training for Sustained Functional Independence.

This randomized controlled trial examined the effects of digital cognitive training (DCT) on cognition and functionality in older adults with Mild Neurocognitive Disorder.

Geriatr Gerontol IntSep 26, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Rethinking Prevention of Recurrent Bacterial Vaginosis: A Comparative Effectiveness Network Meta-Analysis.

This network meta-analysis evaluated the effectiveness of various preventive strategies for recurrent bacterial vaginosis (BV) in nonpregnant women.

J Low Genit Tract DisSep 26, 2026Read summary
Case ReportGastroenterology

Vulvar Crohn's-Case Series and Review of Treatment With Ustekinumab.

This case series presents three patients with cutaneous vulvar Crohn's disease (VCD), a rare and challenging condition. Each patient was treated with different biologic agents.

J Low Genit Tract DisSep 26, 2026Read case
Clinical ResearchHematologyOpen access

ATM mutations in myelodysplastic neoplasms, acute myeloid leukemia, and myeloproliferative neoplasms: a systematic review.

This systematic review evaluated the impact of ATM mutations in myelodysplastic neoplasms (MDS), acute myeloid leukemia (AML), and myeloproliferative neoplasms (MPN).

Med OncolSep 25, 2026Read summary
Clinical ResearchNeurology

Wearable Sensors in Gait Assessment for Parkinson Disease and Stroke in Real-World Environments: Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the use of wearable sensors for gait assessment in patients with Parkinson disease (PD) and stroke. It included 43 studies, primarily focusing on PD (2774 participants).

J Med Internet ResSep 25, 2026Read summary
Clinical ResearchUrologyOpen access

Unravelling deregulated metabolites in seminal plasma of infertile men: a systematic review and bioinformatic analysis.

This systematic review analyzed metabolomic studies comparing seminal plasma metabolites in healthy and infertile men. It included 20 studies and identified 284 metabolites, with specific alterations linked to…

J Mol Med (Berl)Sep 25, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Comparative pain relief and functional outcomes following robotic-assisted versus conventional total knee arthroplasty: a GRADE-assessed meta-analysis with meta-regression of randomized controlled trials.

This meta-analysis of 24 randomized controlled trials involving 3,425 patients compared robotic-assisted total knee arthroplasty (RA-TKA) with conventional TKA (C-TKA).

J Robot SurgSep 25, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Effectiveness of digital interventions for menopausal symptoms and cardiometabolic outcomes among women undergoing the menopausal transition: A systematic review and meta-analyses.

This systematic review and meta-analysis assessed digital health interventions for menopausal symptoms and cardiometabolic outcomes in women undergoing the menopausal transition.

MaturitasSep 25, 2026Read summary
Clinical ResearchPhysical Medicine & RehabilitationOpen access

Comparative efficacy of brain-computer interface-coupled robotic rehabilitation, robot-assisted therapy, and motor imagery for upper-limb motor recovery after stroke: a systematic review and network meta-analysis.

This systematic review and network meta-analysis evaluated the efficacy of brain-computer interface-coupled robotic rehabilitation (BCI-robot), robot-assisted therapy, motor imagery, and conventional rehabilitation for…

Neurol SciSep 25, 2026Read summary
Clinical ResearchGeriatricsOpen access

Metabolic reserve: baseline cholesterol as a predictor and modulator of response to in-hospital exercise in older adults.

This secondary analysis of a randomized controlled trial examined whether baseline nutritional biomarkers predicted functional response to multicomponent exercise among 303 hospitalized adults aged ≥75 years.

J Nutr Health AgingSep 25, 2026Read summary
Case ReportInfectious DiseasesOpen access

Aggressive brainstem listeria abscess in an immunocompetent individual: A case report.

An immunocompetent patient in their late 50s presented with neurolisteriosis characterized by multifocal brainstem abscesses. The case involved an extensive negative infectious workup and a complex antibiotic regimen.

Neurol SciSep 25, 2026Read case
Clinical ResearchPulmonology

Predictors of Pulmonary Complications After Rib Fractures: Systematic Review and Meta-Analyses.

This systematic review and meta-analysis examined multivariable-adjusted predictors of pulmonary complications in adults with blunt rib fractures.

J Surg ResSep 25, 2026Read summary
Clinical ResearchDermatologyOpen access

Association Between Metabolic and Bariatric Surgery and Melanoma Risk: A Systematic Review and Meta-analysis of Observational Studies.

This systematic review and meta-analysis of observational studies assessed whether metabolic and bariatric surgery (MBS) was associated with melanoma incidence compared with no MBS.

Obes SurgSep 25, 2026Read summary

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