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1999 articles
September 202624
Cervical aortic arch with severe left ventricular dysfunction in a neonate: successful repair using whole-body perfusion.
A neonate presented with a right cervical aortic arch, coarctation, and significantly reduced left ventricular function. Surgical intervention involved arch repair with aortic uncrossing, utilizing whole-body perfusion…
The Use of Waivers of Guardian Permission in the United States for Pediatric Digital Health Intervention Research Since 2020: Systematic Review.
This systematic review examined the use of guardian permission waivers in pediatric digital health intervention research in the U.S. from 2020 to 2026.
Blood pressure targets for hypertension in people with diabetes mellitus.
This Cochrane systematic review protocol aims to evaluate whether lower blood pressure targets (≤ 130/85 mmHg) reduce mortality and morbidity compared to standard targets (≤ 140 to 160/90 to 100 mmHg) in individuals…
A previously unreported ELOVL4 frameshift variant in a patient with early severe cognitive decline, parkinsonism, and cerebellar ataxia: A case report.
A 35-year-old man presented with a 5-year history of progressive cognitive decline, parkinsonism, and cerebellar ataxia. Neurological examination revealed significant motor and cognitive impairments, with imaging…
Temporally Based Orbicularis Oculi Myocutaneous Flap for Pediatric Postexcisional Cicatricial Lower Eyelid Ectropion: A Case Report.
A pediatric patient developed cicatricial lower eyelid ectropion after two local excisions of a congenital melanocytic nevus at another institution.
Fasting-induced metabolic reprogramming as a therapeutic vulnerability in cancer: a systematic mechanistic review of in vitro evidence.
This systematic review evaluated in vitro studies on fasting and fasting-mimicking interventions in cancer cell models. It found that fasting consistently reduced IGF-1 signaling and inhibited key metabolic pathways…
The reduction in blood pressure required to reduce arterial stiffness components in SPRINT: a randomized controlled trial.
This analysis of the multicentre SPRINT randomised controlled trial examined whether blood pressure changes were associated with changes in arterial stiffness components over 1 year.
Iberdomide plus daratumumab and dexamethasone versus daratumumab, bortezomib, and dexamethasone in patients with relapsed or refractory multiple myeloma (EXCALIBER-RRMM): an open-label, randomised, controlled, phase 3 trial.
EXCALIBER-RRMM is an ongoing, open-label, randomised phase 3 trial comparing iberdomide, daratumumab, and dexamethasone with daratumumab, bortezomib, and dexamethasone in adults with relapsed or refractory multiple…
Effects of exercise interventions on gait, motor function, and balance in patients with Parkinson's disease: A meta-analysis with clinical implications.
This meta-analysis evaluated the effects of exercise interventions on gait, motor function, and balance in 714 patients with Parkinson's disease.
Radiotherapy versus observation following surgical resection of WHO grade 2 atypical meningioma (ROAM/EORTC-1308): an international, multicentre, open-label, phase 3, randomised controlled trial.
ROAM/EORTC-1308 was an international, multicentre, open-label, phase 3 randomised trial comparing adjuvant radiotherapy with observation after complete resection of newly diagnosed WHO grade 2 atypical meningioma.
Levels of IgG subclasses 1-4 in BT595, a 10% IVIG: A sub-analysis of a clinical trial.
This multicenter, open-label clinical trial evaluated the pharmacokinetics of IgG subclasses in patients with primary immunodeficiency receiving 10% IVIG BT595.
Effectiveness of cognitive behavioral therapy for postpartum depression: a systematic review and meta‑analysis.
This systematic review and meta-analysis assessed cognitive behavioral therapy (CBT) for postpartum depression (PPD), comparing it with usual care in randomized controlled trials.
Asthma Intervention with Residential Ventilation and Air Cleaner (AIRVAC) Study: A 4-arm parallel-group randomized controlled trial protocol.
The AIRVAC study is a 4-arm parallel-group randomized controlled trial evaluating the long-term effectiveness of energy recovery ventilators and portable air cleaners in improving asthma outcomes among children and…
Migration of an ingested orthodontic retainer into the psoas muscle presenting with radiculopathy-like symptoms: A case report.
A 26-year-old man presented with abdominal pain after swallowing an orthodontic retainer. Although his abdominal pain improved, he later experienced persistent right lower-limb paresthesia and pain.
Nonlinear dose-response of mind-body exercise in older adults with mild cognitive impairment: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the dose-response relationship of mind-body exercise on cognitive function in older adults with mild cognitive impairment (MCI).
Progression-free survival and objective response rate as a surrogate end point for overall survival in metastatic renal cell carcinoma: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the validity of progression-free survival (PFS) and objective response rate (ORR) as surrogate endpoints for overall survival (OS) in randomized controlled trials of…
Can we do better in identifying child developmental conditions early? Sensitivity and specificity of the Watch Me Grow Integrated (WMG-I) digital developmental screening and surveillance tool in Australia.
This randomized controlled trial evaluated the diagnostic accuracy of the 'Watch Me Grow Integrated' (WMG-I) digital developmental screening tool in 16-to-35-month-old children in Australia.
Multimorbidity and the risk of depression: a systematic review of cohort studies.
This systematic review evaluated the longitudinal association between multimorbidity and the risk of developing depression, analyzing 17 cohort studies.
Western versus Asian utilization of molecular testing for indeterminate thyroid nodules: A meta-analysis of divergent clinical impact.
This meta-analysis examined the use of molecular testing (MT) for indeterminate thyroid nodules in Western and Asian populations.
Accuracy of Artificial Intelligence in Diagnosing Obstructive Sleep Apnea Using Photoplethysmography: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the diagnostic accuracy of AI-based methods using photoplethysmography (PPG) for obstructive sleep apnea (OSA) in adults.
Sequential combination of anti-PD-1 antibody and PEG-IFNα in chronic hepatitis B patients: correlates of HBsAg loss with enhanced T-cell responses.
This pilot clinical trial investigated the sequential combination of anti-PD-1 antibody (sintilimab) and PEG-IFNα in ten virologically suppressed chronic hepatitis B patients.
Bispectral index during remimazolam versus propofol sedation at matched depths: a randomized, double-blind crossover trial in healthy volunteers.
This randomized, double-blind crossover trial evaluated the bispectral index (BIS) during remimazolam versus propofol sedation in 16 healthy volunteers.
Pure Red Cell Aplasia Following Neoadjuvant Docetaxel/Carboplatin/Trastuzumab (TCbH) in a 45‑Year‑Old Woman With Breast Cancer Successfully Treated With Cyclosporine.
A 45-year-old woman with HER2-positive breast cancer developed pure red cell aplasia (PRCA) after neoadjuvant treatment with docetaxel/carboplatin/trastuzumab.
Losartan with add-on spironolactone for severe COVID-19 in the intensive care unit: a randomized controlled trial.
This randomized, open-label, parallel-group trial at five intensive care units in Marseille evaluated losartan, with conditional spironolactone, added to standard care for adults with severe COVID-19-related respiratory…
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