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1998 articles

October 202624

Clinical ResearchMedical Genetics

The extra X chromosome and autoimmune susceptibility in Klinefelter syndrome.

This systematic review and meta-analysis assessed autoimmune susceptibility in people with Klinefelter syndrome (47,XXY), using studies of autoimmune disease and serological markers.

J Clin Endocrinol MetabOct 16, 2026Read summary
Clinical ResearchAnesthesiology

Nociception Level-Guided Multimodal Analgesia with External Oblique Intercostal Plane Block in Laparoscopic Cholecystectomy.

This double-blind randomized controlled trial compared nociception level (NOL)-guided multimodal analgesia (MMA) incorporating an external oblique intercostal plane (EOIP) block with intravenous dexketoprofen alone in…

J Vis ExpOct 16, 2026Read summary
Clinical ResearchOncology (Medical)

Impact of Phosphatidylinositol 3-Kinase and B-Raf Mutations in Rat Sarcoma Wild-Type Metastatic Colorectal Cancer.

This systematic review and meta-analysis assessed whether PIK3CA and BRAF mutations were associated with outcomes among patients with RAS wild-type metastatic colorectal cancer receiving first-line EGFR inhibitor…

J Vis ExpOct 16, 2026Read summary
Case ReportPulmonology

Life-threatening diffuse alveolar hemorrhage associated with Rhinovirus infection and the potential role of corticosteroids in immunocompetent patients: Case reports.

Two immunocompetent women, aged 85 and 70, presented with severe hypoxemia and hemoptysis or worsening dyspnea. Chest CT showed diffuse or bilateral ground-glass opacities and consolidations.

Medicine (Baltimore)Oct 16, 2026Read case
Clinical ResearchCardiology

Dapagliflozin After Transcatheter Aortic Valve Implantation According to Frailty in DapaTAVI Trial.

This post hoc analysis of the multicenter randomized DapaTAVI trial examined whether frailty modified dapagliflozin’s effects after transcatheter aortic valve implantation.

J Am Heart AssocOct 16, 2026Read summary
Clinical ResearchNephrology

Local ancestry-aware genome-wide meta-analysis uncovers novel genetic loci for sickle cell disease nephropathy.

This local ancestry-aware genome-wide association meta-analysis examined estimated glomerular filtration rate in participants from two well-characterized adult sickle cell disease cohorts, seeking genetic loci…

Blood AdvOct 16, 2026Read summary
Clinical ResearchCardiology

Artificial intelligence-enhanced electrocardiography for predicting mortality and major adverse cardiovascular events: A systematic review and narrative synthesis.

This systematic review and narrative synthesis evaluated AI-enabled 12-lead or single-lead ECG models for predicting all-cause mortality, cardiovascular mortality, and major adverse cardiovascular events in adults.

PLoS OneOct 16, 2026Read summary
Case ReportPediatrics

Cardiac arrest in an adolescent following an overdose of antidepressants comprising sertraline, quetiapine fumarate, and lamotrigine: Case report.

An 11-year-old with depression ingested large quantities of sertraline (3 g), quetiapine fumarate (5 g), and lamotrigine (3 g).

Int J Clin Pharmacol TherOct 16, 2026Read case
Clinical ResearchGeriatrics

Effectiveness of traditional mind-body exercises on fall risk test scores and balance in older adults: A systematic review and meta-analysis.

This systematic review and meta-analysis pooled 31 randomized controlled trials involving 3,622 older adults to assess traditional mind-body exercises and fall-risk test scores and balance.

Medicine (Baltimore)Oct 16, 2026Read summary
Case ReportGastroenterology

Acute colonic variceal bleeding treated with coil-assisted retrograde transvenous obliteration following atezolizumab-bevacizumab therapy for advanced hepatocellular carcinoma: A case report.

A 66-year-old man with alcohol-related cirrhosis and advanced hepatocellular carcinoma developed hematochezia the day after starting atezolizumab plus bevacizumab.

Medicine (Baltimore)Oct 16, 2026Read case
Case ReportNeurosurgery

Bilateral lower limb dysfunction due to acute hematoma in the lumbar ligamentum flavum: A case report and literature review.

A 71-year-old man developed sudden lower back pain without an identifiable trigger, followed by worsening pain, numbness, and weakness in both legs.

Medicine (Baltimore)Oct 16, 2026Read case
Case ReportNeurology

Spontaneous gene mutation encounters a paternal genetic variant: Nemaline myopathy: a case report and literature review.

A 21-year-old man had progressive weakness beginning in the distal lower limbs at age 3, later affecting proximal and masticatory muscles.

Medicine (Baltimore)Oct 16, 2026Read case
Case ReportOncology (Medical)

Tislelizumab-induced hyperamylasemia: Case report and safety analysis using the FAERS database.

A 69-year-old patient developed hyperamylasemia after six cycles of combination immunotherapy with pemetrexed, tislelizumab, and carboplatin. The authors attributed the elevated amylase to tislelizumab.

Int J Clin Pharmacol TherOct 16, 2026Read case
Case ReportNephrology

Crystalline κ light-chain proximal tubulopathy and Auer rod-like inclusions presenting as Fanconi syndrome: A case report.

A 53-year-old man presented with Fanconi syndrome, with hypokalemia, hypophosphatemia, mild metabolic acidosis, and renal glucosuria.

Clin NephrolOct 16, 2026Read case
Case ReportDermatology

Tranilast/roxithromycin with topical tacrolimus in refractory atopic facial eczema: Case report.

A 30-year-old man with atopic dermatitis had facial eczema and severe itching that persisted despite conventional treatment, including oral betamethasone.

Int J Clin Pharmacol TherOct 16, 2026Read case
Case ReportEmergency MedicineOpen access

Seizures Secondary to Aconitum Plant Poisoning: a case report.

A 53-year-old man developed ventricular tachycardia progressing to ventricular fibrillation and cardiac arrest after drinking homemade Aconitum kusnezoffii-infused liquor.

J Med Case RepOct 16, 2026Read case
Case ReportPulmonology

Influenza A (H1N1) virus infection complicated by checkpoint inhibitor pneumonitis: A case report.

After neoadjuvant immunotherapy, a patient developed respiratory dysfunction and progressive pulmonary lesions. Imaging and positive influenza A (H1N1) testing, interpreted alongside the immunotherapy history and…

Medicine (Baltimore)Oct 16, 2026Read case
Case ReportEndocrinology

Approach to the patient with APS-1/APECED.

This article presents five cases of autoimmune polyendocrine syndrome type 1 (APS-1/APECED), a disorder caused by impaired immune tolerance and typically associated with biallelic AIRE variants.

J Clin Endocrinol MetabOct 16, 2026Read case
Clinical ResearchObstetrics & GynecologyOpen access

Safety and efficacy of a novel miniaturized robotic assisted surgery system in hysterectomy: a prospective, investigational device exemption clinical trial.

This prospective, multicentre, non-randomised Investigational Device Exemption trial assessed the safety and effectiveness of the MIRA miniaturized robotic system for benign hysterectomy.

J Robot SurgOct 16, 2026Read summary
Clinical ResearchEndocrinology

Efficacy and safety of imeglimin hydrochloride for metabolic dysfunction-associated steatotic liver disease with type 2 diabetes: Single-center, single-arm phase 2 (IMELD study).

This single-center, single-arm phase 2 interventional study assessed 24 weeks of imeglimin in patients with metabolic dysfunction-associated steatotic liver disease (MASLD) and type 2 diabetes.

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchPsychiatry

Moxibustion for depression: A meta-analysis.

This meta-analysis assessed moxibustion, alone or alongside other therapies, for depression. It included 15 randomized controlled trials with 1510 patients, comparing moxibustion with sham treatment, no treatment, or…

Medicine (Baltimore)Oct 16, 2026Read summary
Case ReportCardiothoracic Surgery

En bloc excision of a large hydatid cyst originating from the posterior wall of the left ventricle.

A male patient was found incidentally to have a hydatid cyst arising from the posterior wall of the left ventricle. The cyst was completely removed en bloc through a left ventriculotomy.

Multimed Man Cardiothorac SurgOct 16, 2026Read case
Case ReportCardiothoracic Surgery

Large Carinal Chondrosarcoma: Resection of the Main Carina, Distal Trachea, and Orifices of the Mainstem Bronchi and Construction of a New Carina.

A 23-year-old man presented with dyspnea, fatigue, and cough. CT showed a lobulated mass anterior to the distal trachea and main carina; bronchoscopy demonstrated carinal widening, significant stenosis of both mainstem…

Am J Case RepOct 16, 2026Read case
Clinical ResearchOncology (Medical)

Three traditional Chinese patent medicines combined with transarterial chemoembolization for primary liver cancer: A systematic review and Bayesian network meta-analysis.

This systematic review and Bayesian network meta-analysis assessed three traditional Chinese patent medicines combined with transarterial chemoembolization (TACE) for primary liver cancer.

Medicine (Baltimore)Oct 16, 2026Read summary

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