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1998 articles
October 202624
Emerging risks of health optimisation: refractory nausea associated with peptide injections reported to contain retatrutide.
A woman in her mid-20s presented with five days of persistent nausea, repeated vomiting, loose stools and markedly reduced oral intake.
Meckel's diverticulum leading to axial torsion and volvulus of the small bowel.
A patient presented with small-bowel obstruction caused by a giant Meckel’s diverticulum measuring 22 cm × 11 cm × 9.8 cm. The diverticulum produced mass effect and was associated with axial torsion and volvulus of the…
Fregoli syndrome in an adolescent with Moyamoya disease.
An early adolescent with known Moyamoya disease developed acute psychosis after a febrile illness accompanied by headache and vomiting.
Early interventions for primary care patients with stress-related mental ill health: a randomised controlled non-inferiority trial of a nurse-led collaborative care intervention versus cognitive behavioural therapy.
This randomised controlled non-inferiority trial compared nurse-led collaborative care (CC) with psychologist-guided self-help cognitive behavioural therapy (GSH-CBT) in 172 adults with mild to moderate stress-related…
Atypical presentations of Lhermitte's sign after treatment for human papillomavirus-associated oropharyngeal squamous cell carcinoma.
Two patients with human papillomavirus-associated oropharyngeal squamous cell carcinoma developed Lhermitte’s sign after chemoradiotherapy.
Preoperative pathways in adults with multiple long-term conditions undergoing major surgery: a systematic review.
This systematic review examined preoperative interventions, pathways and protocols for adults with multiple long-term conditions (MLTCs) undergoing major surgery.
Adult diagnostic reference levels in computed tomography: A systematic review and analysis of regional variability.
This systematic review examined adult computed tomography diagnostic reference levels (DRLs) across regions and examination types.
Effectiveness of psychosocial interventions addressing informal caregivers' mental health: an umbrella systematic review with 26,481 participants.
This umbrella systematic review and random-effects meta-analysis assessed psychosocial interventions for the mental health of informal caregivers, grouped by care recipients’ clinical conditions.
Challenging historical associations and reassuring women: an updated meta-analysis of multiple sclerosis relapse risk following assisted reproductive technology.
This systematic review and random-effects meta-analysis examined whether assisted reproductive technology (ART) is associated with multiple sclerosis (MS) relapses in women with MS or incident MS in previously healthy…
MRI-derived radiomics for prostate cancer active surveillance: a systematic review.
This PRISMA 2020 systematic review assessed MRI-derived radiomic and artificial intelligence models for selecting men with prostate cancer for active surveillance, detecting clinically significant cancer at baseline…
The effects of exercise on pulmonary function and respiratory muscle strength in patients with chronic kidney disease: a systematic review and meta-analysis.
This systematic review and meta-analysis examined experimental studies of exercise and respiratory outcomes in people with chronic kidney disease across disease stages. Thirteen studies contributed to the meta-analyses.
Phase 2a Randomized Placebo-Controlled Human Challenge Trial of the Respiratory Syncytial Virus L-Protein Inhibitor S-337395 for Respiratory Syncytial Virus Infection.
This phase 2a, randomized, double-blind, placebo-controlled, single-centre human challenge trial assessed oral S-337395 in healthy adults aged 18–55 years inoculated with RSV-A Memphis 37b.
Immunogenicity and Safety of Co-administration of Adjuvanted Respiratory Syncytial Virus Prefusion F Protein Vaccine With 20-Valent Pneumococcal Conjugate Vaccine in Adults Aged ≥60 Years: A Randomized, Non-inferiority Trial.
This phase III, open-label, randomized non-inferiority trial compared concomitant versus one-month-apart administration of adjuvanted RSV prefusion F protein vaccine (RSVPreF3) and 20-valent pneumococcal conjugate…
Effect of a Single Subanesthetic Dose of Esketamine on Gastrointestinal Recovery After Laparoscopic Colorectal Cancer Surgery: A Randomized, Outcome-Assessor-Blinded, Placebo-Controlled Trial.
Postoperative gastrointestinal dysfunction (POGD) and Postoperative gastrointestinal intolerance (POGI) remain a critical challenge in abdominal surgery, particularly for colorectal cancer patients undergoing…
Synbiotic supplementation leads to gut microbiome communities with functional capacity linked to better brain white matter development in preterm infants.
This secondary analysis of a randomized controlled trial examined whether daily synbiotic and nutritional supplementation could shape gut microbiome function in very and extremely preterm infants, and how those…
Digital health technologies for the prevention and management of urinary tract infections in menopausal women: A systematic review.
This systematic review synthesised evidence on digital technologies for preventing or managing urinary tract infections in menopausal women.
Fractal radiomics as a virtual biopsy in glioma: A systematic review and meta-analysis of molecular status, radiogenomic associations, and survival outcomes.
This systematic review and meta-analysis assessed whether fractal-based imaging features can predict molecular alterations and outcomes in glioma.
T-cell-redirecting therapies in early relapsed multiple myeloma: a systematic review and network meta-analysis.
This systematic review and network meta-analysis compared T-cell-redirecting regimens in randomized phase 3 trials involving patients with multiple myeloma after at least one prior line.
EACTS Expert Consensus Document on aortic valve repair and valve-sparing aortic root replacement procedures.
This EACTS Expert Consensus Document critically reviews evidence on aortic valve repair and valve-sparing aortic root replacement for aortic regurgitation and proximal thoracic aortic aneurysms across age groups.
Parkinsonism with Reduced Striatal Uptake on DAT-SPECT in a Patient Harboring a Novel KCND3 Variant.
A Japanese patient with a novel KCND3 missense variant classified as a variant of uncertain significance had childhood-onset, slowly progressive cerebellar ataxia and asymmetric parkinsonism, a phenotype compatible with…
A Phase 1/2 Dose-Ranging Safety and Immunogenicity Study of mRNA-Based Candidate Pandemic Influenza Vaccines in Healthy Adults.
This randomised phase 1/2 dose-ranging study evaluated the safety, reactogenicity, and immunogenicity of mRNA-1018 pandemic influenza vaccine candidates in healthy adults.
Capsulectomy at Explant: Rethinking Spinal Cord Stimulator Infected Generator Pocket Management in the Immunocompromised-A Case Series.
Two immunocompromised women with spinal cord stimulator (SCS) infections underwent explantation and capsulectomy. The first patient, with ulcerative colitis and psoriatic arthritis, developed granulation tissue and was…
A 45-Year-Old Woman With 30-Year History of a Nodule of the Earlobe Diagnosed as Lupus Vulgaris (Cutaneous Tuberculosis).
A 45-year-old woman had a painless, intermittently itchy lesion on her right earlobe for more than 30 years. It appeared as a red, thickened plaque with yellow papules and pustules.
Janus kinase inhibitors in the management of lichen planus: a systematic review.
Lichen planus (LP) is a chronic, lymphocytic, inflammatory skin disorder that can affect the skin, hair follicles, nails, and mucous membranes. It has limited treatment options.
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