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1999 articles
September 202624
Prognostic Models for Predicting the Severity and Mortality in People With Acute Pancreatitis - A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed how accurately four clinical scoring systems predict severe acute pancreatitis (SAP) and mortality in adults.
Clinical Reasoning: A 60-Year-Old Woman With Fever, Headache, Diplopia, and Unilateral Periorbital Swelling.
A 60-year-old woman presented with fever, headache, horizontal diplopia, and unilateral periorbital swelling after experiencing recurrent gingival swelling and pain for about a month.
Masked polycythaemia vera presenting with extensive splanchnic venous thrombosis and mesenteric ischaemia.
A woman in her 60s with masked polycythaemia vera (PV) presented with extensive splanchnic venous thrombosis and mesenteric ischaemia after 5 years of management with phlebotomy and aspirin.
Age and antiplatelet de-escalation after myocardial infarction in the TALOS-AMI trial.
This secondary analysis of the TALOS-AMI randomized trial evaluated the effects of de-escalating from ticagrelor to clopidogrel on clinical outcomes in patients after myocardial infarction, stratified by age.
Effectiveness of psychosocial counselling on treatment adherence among patients with a new tuberculosis diagnosis in primary care: a study protocol for a cluster-randomised controlled trial.
This study protocol outlines a cluster-randomised controlled trial aimed at evaluating the effectiveness of psychosocial counselling on treatment adherence among newly diagnosed tuberculosis patients in primary care…
Methods for a Community-Engaged Randomized Trial for Urgency Incontinence.
The Beta-Agonist versus ONA Trial for Urgency Urinary Incontinence (BEST) is a multicenter, single-blinded randomized trial comparing the efficacy of beta-agonist medication and onabotulinumtoxinA injections in female…
Effectiveness, Mediators and Moderators of Remote Live vs. Pre-Recorded Physical Exercise Training for Chronic Low Back Pain.
This randomized controlled trial evaluated the effectiveness of live interactive versus pre-recorded remote exercise training for chronic low back pain (CLBP) in 94 patients.
The association between disability and mortality among children and adolescents: A systematic review and meta-analysis.
This systematic review and meta-analysis examined all-cause mortality among children and adolescents with disabilities compared to non-disabled peers, analyzing 29 studies with over 35 million participants.
Safety and efficacy of human gingiva-derived mesenchymal stem cells in patients with type 1 diabetes: a double-blind, randomized, placebo-controlled, phase 1 trial.
This phase 1 double-blind, randomized, placebo-controlled trial evaluated the safety and efficacy of human gingiva-derived mesenchymal stem cells (GMSCs) in 18 patients with type 1 diabetes mellitus (T1DM).
8 weeks versus 12 weeks of sofosbuvir-velpatasvir for treatment-naive, non-cirrhotic, chronic hepatitis C (RESOLVE): a multicentre, open-label, non-inferiority, randomised controlled trial in India.
The RESOLVE multicentre, open-label, randomised non-inferiority trial compared 8 versus 12 weeks of daily sofosbuvir-velpatasvir in treatment-naive adults with chronic hepatitis C without cirrhosis at five publicly…
Cardiovascular safety of orforglipron versus insulin glargine in adults with type 2 diabetes at increased cardiovascular risk (ACHIEVE-4): a phase 3, event-driven, randomised, open-label, non-inferiority, active comparator trial.
ACHIEVE-4 was a phase 3, event-driven, multicentre, randomised, open-label, active-comparator non-inferiority trial comparing once-daily oral orforglipron with titrated insulin glargine in adults with type 2 diabetes…
More than meets the eye: A meta-analysis of visual outcomes following clipping, coiling, and flow diversion for visually symptomatic paraclinoid aneurysms.
This PRISMA-compliant systematic review and random-effects meta-analysis compared visual outcomes after clipping, coiling, and flow diversion for paraclinoid aneurysms, drawing on 21 studies.
Metastatic melanoma presenting with paraneoplastic dermatomyositis mimicking polymyalgia rheumatica.
A man in his late 70s presented with bilateral shoulder and hip girdle pain, morning stiffness, and significant weight loss over six weeks.
Genetic Analysis and Reproductive Intervention in a Duchenne Muscular Dystrophy Family With Cryptic Complex Chromosomal Rearrangement Identified by Structural Variation Sequencing.
Duchenne/Becker muscular dystrophy (DMD/BMD) is caused by variants in the X-linked DMD gene-most commonly deletions, duplications, or point mutations, and only rarely by complex chromosomal rearrangements (CCRs).
Coffee consumption and head and neck cancer risk: a dose-response and site-specific meta-analysis.
This meta-analysis examined the relationship between coffee consumption and head and neck cancer (HNC) risk across 30 studies.
16S rRNA Datasets of Gut Microbiota in Stent-Based Diverting Technique and Ileostomy from A Prospective, Open-Label, Multicenter Randomized Controlled Trial.
This study presents a 16S rRNA amplicon dataset from a multicenter randomized controlled trial involving 80 patients undergoing either a stent-based diverting technique (SDT) or ileostomy after rectal cancer surgery.
When two rare diseases meet: atypical hemolytic uremic syndrome and alkaptonuria in two siblings.
Two brothers from a consanguineous family presented with recurrent episodes of atypical hemolytic uremic syndrome (aHUS) characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury.
FAT1-associated membranous nephropathy after hematopoietic stem cell transplantation: a case report and review of the literature.
A 55-year-old man developed nephrotic syndrome 52 months post-allogeneic hematopoietic stem cell transplantation for acute lymphoblastic leukemia.
A community-based participatory research and community health workers-led health education strategy for schistosomiasis control among schoolchildren in Pemba Island, Zanzibar: a cluster-randomized trial.
This cluster-randomized controlled trial evaluated a community-based participatory research (CBPR) approach led by community health workers for schistosomiasis control among schoolchildren in Pemba, Zanzibar.
Perioperative Offloading for Diabetic Foot Ulcers: A Systematic Review and Evidence Synthesis.
This systematic review evaluated perioperative offloading strategies for diabetic foot ulcer (DFU) management, synthesizing evidence from 15 publications, including guidelines and expert consensus.
Severe upper limb soft tissue infection with compartment syndrome following a scratch injury: a case report.
A 58-year-old female teacher developed a severe soft tissue infection in her left arm following a minor scratch from a student.
Does baseline physical function modify the response to a physical activity intervention in adults with arthritis? A secondary analysis of a randomized trial.
This secondary analysis of a randomized controlled trial examined whether baseline physical function influenced the response to a telephone-delivered Walk With Ease (WWE-T) intervention in 267 adults with arthritis.
Lower HLA-B27 positivity and heterogeneous late-onset case proportions across axial spondyloarthritis cohorts: a systematic review and meta-analysis.
This systematic review and meta-analysis examined late-onset ankylosing spondylitis (AS) and axial spondyloarthritis (axSpA) in clinical cohorts, focusing on cases with onset at or after age 45.
Acute variceal bleeding in a patient with phaeochromocytoma: the critical choice of vasoactive therapy.
A woman in her late 70s with a known left-sided phaeochromocytoma experienced acute variceal bleeding, likely due to cirrhosis. Due to the risk of hypertensive crisis, terlipressin was not used.
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