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1998 articles

October 202624

Clinical ResearchNeurologyOpen access

Real-world safety and efficacy of lecanemab in the treatment of Alzheimer's disease: a systematic review and meta-analysis.

This systematic review and meta-analysis pooled real-world studies of lecanemab treatment in people with Alzheimer’s disease, including 37 studies.

J NeurolOct 21, 2026Read summary
Clinical ResearchPsychiatry

"The Effect of Forgiveness Psychoeducation on Death Anxiety, Caregiver Burden, and Forgiveness Tendencies in Caregivers of Patients at the End of Life: A Randomized Controlled Trial": Şahin 49(3) May/June 2026.

This randomized controlled trial evaluated forgiveness psychoeducation for 56 caregivers of patients at the end of life, with 28 assigned to the intervention and 28 to a no-intervention control group.

Cancer NursOct 21, 2026Read summary
Clinical ResearchEndocrinology

Baseline Serum Metabolites as Predictors of Teplizumab Response in Individuals With Type 1 Diabetes.

This analysis examined whether baseline serum metabolites could predict response to teplizumab in 41 people newly diagnosed with type 1 diabetes who participated in the randomized AbATE trial.

DiabetesOct 21, 2026Read summary
Case ReportGeneral Surgery

Duplicated Appendix With Mucocele Mimicking an Appendiceal Neoplasm in a 45-Year-Old Woman: A Case Report.

A 45-year-old woman with right lower-quadrant pain and fever had CT evidence of ruptured appendicitis with a loculated peri-appendiceal abscess, which improved after percutaneous drainage and intravenous antibiotics.

Am J Case RepOct 21, 2026Read case
Clinical ResearchOncology (Medical)

The prognostic value of physical functioning on survival in patients with nonsmall cell lung cancer: a systematic review and meta-analysis.

This systematic review and meta-analysis examined whether objectively measured physical functioning predicts survival in adults with nonsmall cell lung cancer (NSCLC), across surgical and nonsurgical treatment groups.

Eur Respir RevOct 21, 2026Read summary
Case ReportDermatology

5-Aminolevulinic acid-based photodynamic therapy used as a long-term management approach for refractory lichen sclerosus.

A 37-year-old man with more than 10 years of genital lichen sclerosus had recurrence after surgical resection, which left permanent anatomical deformity.

J Dermatolog TreatOct 21, 2026Read case
Clinical ResearchPediatrics

Ruxolitinib for the treatment of pediatric acute and chronic steroid-refractory graft-versus-host disease: Efficacy, safety, and outcomes.

This single-center retrospective study assessed ruxolitinib in children under 18 years with steroid-refractory graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.

Hematol Oncol Stem Cell TherOct 21, 2026Read summary
Clinical ResearchRheumatologyOpen access

Association between rheumatic diseases and glaucoma risk: a systematic review and meta-analysis of 5.7 million individuals.

This systematic review and meta-analysis examined glaucoma occurrence and risk among people with rheumatic diseases (RD), drawing on 18 studies with 5,766,143 participants.

Int OphthalmolOct 21, 2026Read summary
Clinical ResearchCardiologyOpen access

Effectiveness of cardiac resynchronization therapy in cancer therapy-related cardiac dysfunction: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis assessed cardiac resynchronization therapy (CRT) outcomes in patients with cancer therapy-related cardiac dysfunction (CTRCD).

Support Care CancerOct 21, 2026Read summary
Case ReportPhysical Medicine & Rehabilitation

Seated Modified Liuzijue Training for Rehabilitation of a Patient with Respiratory Impairment During the Recovery Phase of Stroke: A Case Report.

A patient with respiratory impairment during stroke recovery also had motor dysfunction and balance limitations that made the traditional standing Liuzijue protocol unsuitable.

J Vis ExpOct 21, 2026Read case
Clinical ResearchOphthalmology

ULTRAWIDE-FIELD COLOR FUNDUS IMAGES AND ARTIFICIAL INTELLIGENCE FOR DIAGNOSIS OF DIABETIC RETINOPATHY: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed artificial intelligence (AI) for diabetic retinopathy (DR) evaluation using ultrawide-field fundus images.

RetinaOct 21, 2026Read summary
Case ReportOphthalmology

METASTATIC UROTHELIAL CARCINOMA OF THE BLADDER TO THE RETINA: A CLINICOPATHOLOGIC CORRELATION AND REVIEW OF THE LITERATURE.

A patient with urothelial carcinoma of the bladder had a large yellow-white lesion in the superotemporal retina of the left eye.

RetinaOct 21, 2026Read case
Case ReportCardiology

Spiked Helmet Sign in the Early Post-Heart Transplantation Period: A Dramatic STEMI Mimic in a Structurally Normal Donor Heart.

A 36-year-old woman with severe dilated cardiomyopathy underwent heart transplantation and subsequently developed subarachnoid hemorrhage and septic shock.

Ann Noninvasive ElectrocardiolOct 21, 2026Read case
Clinical ResearchHematology

The role of allogeneic hematopoietic stem cell transplantation in adults with mature T-cell lymphomas.

This Cochrane systematic review and meta-analysis assessed allogeneic stem cell transplantation (alloSCT) for adults with mature T-cell lymphomas (MTCL), as first-line or salvage treatment.

Cochrane Database Syst RevOct 21, 2026Read summary
Case ReportPathology (Anatomic & Clinical)Open access

Co-occurrence of aortic dissection and polycystic kidney disease: a case report.

A 19-year-old Caucasian man with no known medical history collapsed during sexual intercourse and died. Post-mortem examination found hemopericardium and aortic dissection in association with polycystic kidney disease…

J Med Case RepOct 21, 2026Read case
Clinical ResearchRheumatology

Calorie-Restricted DASH, Carbohydrate-Restricted, and Low-Purine Diets for Weight Loss and Urate Control in Men With Overweight or Obesity and Hyperuricemia: A Randomized Trial.

This 12-week, open-label, active-comparator randomized trial compared calorie-restricted carbohydrate-restricted, DASH, and low-purine balanced diets in 102 men with overweight or obesity and hyperuricemia.

Diabetes CareOct 21, 2026Read summary
Clinical ResearchUrology

Extended Ceftriaxone Prophylaxis and Postoperative Inflammation and Infection-Related Symptoms After Ureteral Lithotripsy with Negative Urine Cultures.

This single-center exploratory study, reported as randomized, compared extended preoperative ceftriaxone with a single prophylactic dose in 252 patients with negative urine cultures undergoing rigid ureteroscopic…

J Vis ExpOct 21, 2026Read summary
Clinical ResearchPediatricsOpen access

Parent-child discrepancies in health-related quality of life in pediatric celiac disease: a systematic review and meta-analysis.

This systematic review and meta-analysis examined child–parent differences in health-related quality of life (HRQoL) among children and adolescents with celiac disease, using the disease-specific CDDUX questionnaire.

Eur J PediatrOct 21, 2026Read summary
Clinical ResearchEndocrinology

Excess Liver Fat in Type 2 Diabetes Stratified by Intrapancreatic Fat Deposition: A Meta-Analysis of Dual-Organ MRI Studies.

This meta-analysis pooled dual-organ MRI studies comparing liver fat content (LFC) in people with type 2 diabetes (T2DM) and non-diabetic controls, and examined whether study-level intrapancreatic fat deposition (IPFD)…

Liver IntOct 21, 2026Read summary
Clinical ResearchEndocrinology

The Effect of Obesity on the α-Cell Response to Hyperglycemia in the Presence of Amino Acids.

This randomized, two-occasion study examined how amino acids affect glucagon suppression during graded glucose infusion in lean participants and participants with obesity, with or without hepatic steatosis.

DiabetesOct 21, 2026Read summary
Case ReportOphthalmologyOpen access

Use of the 590-nm CAPSULaser in true open-sky penetrating keratoplasty triple procedures: a technical report of two cases.

Two eyes with advanced corneal opacity and visually significant cataract underwent combined penetrating keratoplasty, cataract extraction, and intraocular lens implantation.

Int OphthalmolOct 21, 2026Read case
Case ReportDermatologyOpen access

Inherited epidermal differentiation disorders (EDD) in pediatric patients from a single Italian referral Center.

A retrospective review at an Italian referral center described three children with congenital, clinically heterogeneous inherited epidermal differentiation disorders.

Eur J PediatrOct 21, 2026Read case
Clinical ResearchOphthalmology

EFFICACY AND SAFETY OF SUBTHRESHOLD LASER IN PATIENTS WITH ACUTE CENTRAL SEROUS CHORIORETINOPATHY: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis assessed the efficacy and safety of subthreshold laser for acute central serous chorioretinopathy (CSC), including six randomized controlled trials with 401 participants.

RetinaOct 21, 2026Read summary
Case ReportMedical GeneticsOpen access

Clinically isolated hearing loss as a mild phenotype of PEX26-associated peroxisomal biogenesis disorder: A case report, literature review, and in silico analysis.

An Iranian man presented with bilateral sensorineural hearing loss (SNHL) and no other clinical manifestations at evaluation.

Mol Biol RepOct 21, 2026Read case

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