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1998 articles

October 202624

Case ReportHematologyOpen access

HHV8-associated multicentric Castleman disease with Kaposi sarcoma in an immunocompetent patient: a case report and review of the literature.

A 57-year-old man presented with five months of generalized lymphadenopathy, weakness, cough, fever, and weight loss. HIV, CMV, EBV, and tuberculosis tests were negative.

J HematopOct 24, 2026Read case
Clinical ResearchPsychiatry

Digital Therapeutic Interventions for Suicide Prevention: A Systematic Review and Meta-Analysis of Their Effectiveness in Reducing Suicidal Ideation and Suicide Attempts.

This systematic review and meta-analysis synthesised randomized clinical trials of digital interventions for suicide prevention. Seventeen studies (N = 5.089) were included.

PsicothemaOct 24, 2026Read summary
Case ReportInfectious Diseases

Disseminated Trimethoprim/Sulfamethoxazole-Resistant Nocardiosis in Renal Transplant Recipient, India.

A renal transplant recipient in India taking trimethoprim/sulfamethoxazole prophylaxis presented with fever, hemoptysis, and neurologic deficits.

Emerg Infect DisOct 24, 2026Read case
Case ReportVascular Surgery

A 78-Year-Old Man With a Previously Stable Atherosclerotic Abdominal Aortic Aneurysm Presenting With Impending Rupture Following COVID-19.

A 78-year-old man with a surveilled atherosclerotic abdominal aortic aneurysm (AAA), stable at approximately 43 mm for 2 years, developed COVID-19.

Am J Case RepOct 24, 2026Read case
Clinical ResearchNeurologyOpen access

Mapping the prevalence of Epstein-Barr virus and multiple sclerosis in Middle East and North Africa: a systematic review and meta-analysis.

This systematic review and meta-analysis mapped published estimates of multiple sclerosis (MS) prevalence and Epstein-Barr virus (EBV) seroprevalence in Middle East and North Africa populations.

J NeurovirolOct 24, 2026Read summary
Case ReportOphthalmology

Acquired Corneal Subepithelial Hypertrophy: First Ultrastructural Characterization by Transmission Electron Microscopy.

A 57-year-old man with prior penetrating keratoplasty for trauma and subsequent Descemet stripping automated endothelial keratoplasty developed progressive visual decline from a superficial corneal opacity.

Eye Contact LensOct 24, 2026Read case
Case ReportMedical GeneticsOpen access

Clinical manifestations of Armfield syndrome in females with heterozygous FAM50A variants and skewed X-chromosome inactivation.

A Spanish female patient presented with macrocephaly, global developmental delay, and leukoencephalopathy. Whole-exome sequencing identified a novel de novo heterozygous FAM50A variant, c.905 A > T (p.His302Leu).

Neurol SciOct 24, 2026Read case
Case ReportInfectious Diseases

Systemic Spiroplasma turonicum Infection Manifested as Knee Arthritis, France, 2025.

An immunocompromised patient in southeast France presented with fever, knee arthritis, and skin erythema. Blood and joint samples tested positive for Spiroplasma turonicum, an intracellular gram-negative bacterium…

Emerg Infect DisOct 24, 2026Read case
Case ReportPediatrics

Persistent Microfilaremia Caused by Dirofilaria asiatica Infection in 2-Year-Old Child, Sri Lanka, 2024.

A 2-year-old child in Sri Lanka was found to have a patent infection with Dirofilaria asiatica, a canine filarioid implicated in zoonotic human infection.

Emerg Infect DisOct 24, 2026Read case
Clinical ResearchOncology (Medical)

Stereotactic body radiation therapy for pancreatic cancer: evaluating its efficacy, safety, and future prospects: systematic review.

This systematic narrative review assessed stereotactic body radiation therapy (SBRT) for locally advanced pancreatic cancer, including patients unsuitable for surgery.

Br J RadiolOct 24, 2026Read summary
Clinical ResearchGeriatrics

Informal Caregiver-Observed Fall Risk Indicators and Caregiver Responses to Prevent Falls Among Community-Dwelling Older People: A Systematic Review.

This systematic review synthesized 16 studies of informal caregivers’ observations of fall-risk indicators and their preventive responses among community-dwelling older people.

J Nurs ScholarshOct 24, 2026Read summary
Clinical ResearchDermatologyOpen access

Combination therapy of carbon dioxide laser with topical halometason cream and 308 nm excimer laser for the treatment of vitiligo: an optimized combined treatment protocol.

This randomized controlled trial evaluated fractional CO₂ laser plus topical halometasone cream and 308-nm excimer lamp therapy for refractory non-segmental vitiligo, compared with excimer therapy, a topical calcineurin…

Lasers Med SciOct 24, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Effect of Rapid Rollover on Pneumothorax Rate After Percutaneous CT-Guided Lung Biopsy: A Multisite Randomized Controlled Trial Within a Single Health System.

This prospective, multisite randomized controlled trial evaluated rapid rollover after CT-guided lung biopsy using an anterior or lateral approach.

J Thorac ImagingOct 24, 2026Read summary
Case ReportNeurologyOpen access

Copy number variants across the developmental epilepsy-developmental and epileptic encephalopathy spectrum: an Indonesian case series.

A retrospective series from a tertiary hospital in Yogyakarta described four Indonesian children with developmental epilepsy or developmental and epileptic encephalopathy and pathogenic copy number variants.

NeurogeneticsOct 24, 2026Read case
Clinical ResearchPsychiatryOpen access

Efficacy and safety of GLP-1 receptor agonists for antipsychotic-related overweight and metabolic dysregulation: a systematic review and meta-analysis.

This systematic review and meta-analysis pooled randomized controlled trials of GLP-1 receptor agonists in adults receiving antipsychotic treatment for overweight or metabolic dysregulation.

Eur J Clin PharmacolOct 24, 2026Read summary
Case ReportPediatricsOpen access

Varicella zoster vasculopathy presenting as bilateral subdural haematoma in an infant: case report of a rare case and literature review.

A 6-month-old boy developed chickenpox with fever, irritability, and a vesicular rash. Although the rash and fever resolved, he had persistent irritability, poor feeding, intermittent vomiting, developmental regression…

Childs Nerv SystOct 24, 2026Read case
Clinical ResearchOphthalmology

Influence of capsular tension ring implantation on dynamic in vivo capsular apposition and intraocular lens behavior in highly myopic eyes.

This prospective randomized clinical trial assessed whether capsular tension ring (CTR) implantation affects capsular apposition and intraocular lens (IOL) behavior after cataract surgery in highly myopic eyes.

J Cataract Refract SurgOct 24, 2026Read summary
Clinical ResearchCardiothoracic SurgeryOpen access

Uniportal versus multiportal robotic-assisted thoracic surgery for anatomical pulmonary resection: a systematic review and meta-analysis of perioperative recovery and surgical quality.

This systematic review and meta-analysis compared uniportal/single-port with multiportal robotic-assisted thoracic surgery for anatomical pulmonary resection.

J Robot SurgOct 24, 2026Read summary
Case ReportInfectious Diseases

Dirofilaria asiatica Infection and Asymptomatic Microfilaremia, Sri Lanka, 2025.

During night blood surveillance for lymphatic filariasis in Sri Lanka in 2025, two people were found to have asymptomatic Dirofilaria microfilaremia.

Emerg Infect DisOct 24, 2026Read case
Case ReportInfectious Diseases

Fatal Rickettsia parkeri Rickettsiosis in Immunocompromised Pediatric Patient, Georgia, USA, 2025.

A 3-year-old boy in Georgia, USA, receiving chemotherapy for B-cell acute lymphoblastic leukemia was hospitalized with febrile neutropenia.

Emerg Infect DisOct 24, 2026Read case
Clinical ResearchGeriatrics

A Methodological Framework for a Large Language Model Virtual Companion for Older Adults at Risk of Social Isolation.

This paper presents a methodological framework for developing and evaluating a large language model (LLM)-driven virtual companion for older adults at risk of social isolation.

J Vis ExpOct 23, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Protective effect of N-acetylcysteine on oxaliplatin-induced peripheral neuropathy in colorectal cancer: a randomized controlled trial.

This randomized controlled trial evaluated oral N-acetylcysteine (NAC) for preventing oxaliplatin-induced peripheral neuropathy in 46 patients with stage III or high-risk stage II colorectal cancer receiving adjuvant…

Cancer Chemother PharmacolOct 23, 2026Read summary
Case ReportOncology (Medical)Open access

Successful treatment with BrECADD in a patient with Dubin-Johnson syndrome and classic Hodgkin lymphoma: a case report.

A 26-year-old man with advanced-stage classic Hodgkin lymphoma also had Dubin–Johnson syndrome (DJS) associated with a homozygous ABCC2 variant, c.2291G>A (p.Gly764Asp).

Cancer Chemother PharmacolOct 23, 2026Read case
Clinical ResearchEndocrinology

Search for the glycated hemoglobin target minimizing mortality among people with type 2 diabetes with rare incidence of treatment-related severe hypoglycemia - Epidemiologic analysis of J-DOIT3 randomized controlled trial.

This landmark analysis of the J-DOIT3 randomized controlled trial examined associations between updated HbA1c and cardiovascular outcomes or mortality among people with type 2 diabetes, in a setting where severe…

PLoS OneOct 23, 2026Read summary

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