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2000 articles
October 202624
The role of fibrinogen concentrate in the reduction of allogeneic blood product requirements: a systematic review and meta-analysis.
This systematic review and meta-analysis compared fibrinogen concentrate (FC) with other treatments for acquired hypofibrinogenaemia across clinical settings.
Effect of Oliceridine on Early Postoperative Recovery in Children Undergoing Adenotonsillectomy: A Prospective, Double-Blind, Randomized Controlled Trial.
Children undergoing adenotonsillectomy may be vulnerable to opioid-related adverse effects, creating a need for analgesic strategies that support rapid postoperative recovery.
Comparative efficacy of topical garlic extract and 20% podophyllin solution in the treatment of female genital warts: a triple-blind randomized clinical trial.
This triple-blind randomized clinical trial compared topical 5% garlic extract with 20% podophyllin in 74 women with genital warts, applied weekly for four weeks.
Robotic-assisted versus conventional coronary artery bypass grafting: a systematic review, meta-analysis, and trial sequential analysis of 39,918 patients.
This systematic review and meta-analysis compared robotic-assisted with conventional coronary artery bypass grafting (CABG) across nine observational studies involving 39,918 patients.
Progestogens, cervical cerclage, and cervical pessary for preventing preterm birth in asymptomatic singleton pregnancies with a sonographic short cervix and no previous history of spontaneous preterm birth: systematic review and bayesian network meta-analysis.
This systematic review and Bayesian network meta-analysis compared interventions to prevent preterm birth in asymptomatic women with singleton pregnancies, a sonographic short cervix, and no previous spontaneous preterm…
Effectiveness and safety of target-specific RNA-based lipid-lowering therapies: A systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis of randomized controlled trials assessed the efficacy and safety of RNA-based therapies targeting PCSK9, APOC3, or ANGPTL3 in patients with hyperlipidemia or…
Sustained potassium control and recurrent hyperkalemia during individualized potassium-guided sodium zirconium cyclosilicate titration in maintenance hemodialysis: a post hoc analysis of a randomized trial.
This exploratory post hoc analysis of a single-centre, open-label randomised trial assessed sustained potassium control with individualized potassium-guided sodium zirconium cyclosilicate (SZC) in 116 maintenance…
Negotiating Care Over Time: A Systematic Review of Alzheimer's Disease Caregiving Through a Life Course Approach.
This systematic review examined sociological research published between 2004 and 2024 on family caregiving for people with Alzheimer’s disease, focusing on how caregiving intersects with caregivers’ life trajectories…
Necroptosis as a key player in cervical cancer progression and management: a systematic review and transcriptomic cross-study consensus analysis.
This systematic review and transcriptomic cross-study consensus analysis examined published evidence on necroptosis in cervical cancer, including seven prognostic gene models and exploratory analyses of overlapping…
How Do Mindfulness-Based and Cognitive Behavioral Therapies Help Adults With Opioid-Treated Chronic Low Back Pain? A Qualitative Study.
This qualitative study explored how mindfulness-based therapy (MBT) and cognitive behavioral therapy (CBT) may help adults with chronic low back pain treated with opioids.
Pediatric conjunctival papilloma managed with staged multimodal therapy: a case report.
A 4-year-old boy presented with multifocal conjunctival papillomatous lesions and was diagnosed with conjunctival papilloma. Topical and intralesional interferon alfa-2b were used before surgery to reduce lesion size.
Density Spectral Array Patterns During Total Intravenous Anesthesia with Intravenous Lidocaine for Craniotomy: An Illustrative Two-Case Series.
Two adults undergoing craniotomy for tumor resection received propofol-remifentanil total intravenous anesthesia, bilateral scalp block, and intravenous lidocaine.
Fibrolipomatous Hamartoma of the Median Nerve Misdiagnosed as a Palmar Space Abscess: A Case Report.
A 17-year-old girl had progressive left-hand swelling and paraesthesia over 5 years, followed by pain and reduced grip strength.
Intrafamilial phenotypic variation in four Palestinian siblings with CFAP418-related ciliopathy: a familial case series.
Four Palestinian siblings from a consanguineous family were homozygous for the CFAP418 splice-donor variant NM_177965.3:c.155 + 1G > A.
Can't Name It, Can't Log Off: Alexithymia and Problematic Internet-Related Behaviors: A Systematic Review and Meta-Analysis.
This preregistered systematic review and meta-analysis examined quantitative associations between alexithymia and problematic Internet-related behaviors (PIB), including problematic Internet, smartphone, social media…
Acromegaly as the Initial Presentation of Multiple Endocrine Neoplasia Type 1: A Case Report.
A 34-year-old woman presented with acromegalic features and hypercalcemia. Testing and MRI showed a recurrent growth hormone–secreting pituitary macroadenoma, while neck imaging identified a parathyroid adenoma.
Rouleaux mimicking anti-H in molecularly confirmed para-Bombay siblings: a diagnostic pitfall.
Two siblings from India were found to have a para-Bombay phenotype during evaluation of blood-group serology. In the index case, red cells did not react with anti-H lectin, while weak reactivity with pooled group O red…
Food-Associated Kounis Syndrome: Clinical Spectrum and Diagnostic Considerations from a Case Report and Systematic Qualitative Synthesis of Published Cases.
The supplied abstract does not describe an individual patient’s presentation, diagnostic findings, or outcome. It reports a qualitative synthesis of published food-associated Kounis syndrome cases: 53 patients across 50…
Inhibin B as a biomarker for ovarian reserve and ovarian response: systematic reviews and meta-analyses of diagnostic test accuracy.
This systematic review and meta-analysis assessed the diagnostic accuracy of inhibin B compared with anti-Müllerian hormone (AMH) for ovarian reserve and ovarian response.
Effects of gliflozins on bone health of patients with chronic kidney disease: a systematic review.
This systematic review assessed skeletal safety and bone-related metabolic outcomes with sodium-glucose co-transporter-2 inhibitors (SGLT2i) in people with chronic kidney disease, drawing on randomised trials and…
Impact of Evolocumab on LDL-Cholesterol and Cardiovascular Outcomes in Patients With Established CVD: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis pooled randomised controlled trials of evolocumab in adults with established cardiovascular disease.
EORTC QLQ-C30 symptom components and their functional correlates during adjuvant chemotherapy for early breast cancer: a multivariate analysis. Data from GEICAM/2003-02 study.
This multivariate analysis of data from a multicentre phase III randomised trial examined changes in EORTC QLQ-C30 symptoms and their relationships with functioning among 820 patients with early breast cancer receiving…
Assisted Reproductive Technology and Risk of Congenital Heart Defects in the Offspring: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed congenital heart defect (CHD) risk in offspring conceived through assisted reproductive technology (ART) compared with spontaneous conception.
Impact of HIF-prolyl hydroxylase inhibitors on VEGF expression and vascular adverse events in chronic kidney disease: a meta-analysis of 34 randomized controlled trials.
This meta-analysis of 34 randomized controlled trials assessed VEGF levels and VEGF-related adverse outcomes with hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) in people with chronic kidney disease.
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